Hs00684310_cn

• Gene Symbol: CISH
• Assay Reference Genome Location: Chr.3:50608410 on build GRCh38
• Cytoband: 3p21.2

Target Gene Details

• Entrez Gene ID: 1154
• Gene Name: cytokine inducible SH2 containing protein
• Gene Aliases: BACTS2, CIS, CIS-1, G18, SOCS
• Location: Chr.3:50606454-50611831 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CISH	NM_013324.5	3	542	NP_037456.5
	NM_145071.2	2	385	NP_659508.1
	XM_011533329.2	1	3207	XP_011531631.1
	AF035947.1	1	3352	AAF97410.1
	AF132297.2	3	483	AAD28471.2
	AK313850.1	2	328
	BC031590.1	2	317	AAH31590.1
	BC064354.1	2	222	AAH64354.1
	D83532.1	2	315	BAA92328.1
	DA957793.1	2	385

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3584502	Chr.3:50327055 - 50622310 on Build GRCh38	Gain	NPRL2 C3orf18 TUSC2 RASSF1 CISH CYB561D2 MAPKAPK3 RASSF1-AS1 TMEM115 HEMK1 ZMYND10 CACNA2D2
nsv508919	Chr.3:50596756 - 50676338 on Build GRCh38	Insertion	CISH MAPKAPK3 DOCK3 MIR4787
nsv460533	Chr.3:50536782 - 50640720 on Build GRCh38	Loss	C3orf18 CISH MAPKAPK3 HEMK1
nsv482083	Chr.3:50606455 - 50611831 on Build GRCh38	Gain	CISH

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

kinase modulator

Gene Ontology Categories:

Process(es)

regulation of cell growth
negative regulation of protein kinase activity
protein kinase C-activating G-protein coupled receptor signaling pathway
protein ubiquitination
cytokine-mediated signaling pathway
intracellular signal transduction
negative regulation of JAK-STAT cascade
negative regulation of insulin receptor signaling pathway

Function(s)

molecular_function
protein kinase inhibitor activity
protein binding