Hs00739439_cn

• Gene Symbol: PTPN18
• Assay Reference Genome Location: Chr.2:130358953 on build GRCh38
• Cytoband: 2q21.1

Target Gene Details

• Entrez Gene ID: 26469
• Gene Name: protein tyrosine phosphatase, non-receptor type 18
• Gene Aliases: BDP1, PTP-HSCF
• Location: Chr.2:130356007-130375409 on Build GRCh38
• Assay Gene Location: Overlaps Exon 2 - Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTPN18	NM_001142370.1			NP_001135842.1
	NM_014369.3			NP_055184.2
	XM_006712416.3			XP_006712479.1
	XM_006712417.1			XP_006712480.1
	XM_017003798.1			XP_016859287.1
	AK303804.1
	BC024280.1			AAH24280.1
	BC041562.1			AAH41562.1
	BC052800.1			AAH52800.1
	BI261717.1
	DN995571.1
	X79568.1			CAA56105.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv998333	Chr.2:130059754 - 130454126 on Build GRCh38	Gain+Loss	NOC2LP1 MED15P9 MZT2B CYP4F62P SMPD4 IMP4 TUBA3E POTEF PTPN18 CCDC115 CCDC74B FAR2P2
esv2760631	Chr.2:130005319 - 130400286 on Build GRCh38	Gain+Loss	NOC2LP1 MED15P9 MZT2B SMPD4 FAR2P1 IMP4 TUBA3E POTEF PTPN18 CCDC115 CCDC74B
nsv583133	Chr.2:130281566 - 130390535 on Build GRCh38	Loss	IMP4 PTPN18 CCDC115
dgv7079n54	Chr.2:130181715 - 130391244 on Build GRCh38	Loss	NOC2LP1 MZT2B SMPD4 IMP4 TUBA3E PTPN18 CCDC115
esv3584065	Chr.2:130046530 - 130400286 on Build GRCh38	Loss	NOC2LP1 MED15P9 MZT2B SMPD4 FAR2P1 IMP4 TUBA3E POTEF PTPN18 CCDC115 CCDC74B
nsv583113	Chr.2:130132813 - 130369588 on Build GRCh38	Gain	NOC2LP1 MED15P9 MZT2B SMPD4 IMP4 TUBA3E PTPN18 CCDC115 CCDC74B
nsv520559	Chr.2:130133334 - 130390535 on Build GRCh38	Gain+Loss	NOC2LP1 MED15P9 MZT2B SMPD4 IMP4 TUBA3E PTPN18 CCDC115 CCDC74B
nsv1005664	Chr.2:130159287 - 130649604 on Build GRCh38	Loss	POTEJ CYP4F62P LOC107985778 POTEI TUBA3E CFC1B NOC2LP1 MZT2B SMPD4 CFC1 IMP4 LOC646743 PTPN18 CCDC115 TISP43 FAR2P2
esv2763387	Chr.2:130026123 - 130400286 on Build GRCh38	Loss	NOC2LP1 MED15P9 MZT2B SMPD4 FAR2P1 IMP4 TUBA3E POTEF PTPN18 CCDC115 CCDC74B
dgv7080n54	Chr.2:130185940 - 130390535 on Build GRCh38	Gain	NOC2LP1 MZT2B IMP4 TUBA3E PTPN18 CCDC115
nsv459274	Chr.2:128746961 - 130390535 on Build GRCh38	Loss	MED15P9 LOC389033 LOC151121 FAR2P1 TUBA3E POTEF LOC101927881 NOC2LP1 MZT2B SMPD4 LOC101927924 IMP4 PTPN18 RAB6C CCDC115 RAB6C-AS1 CCDC74B
dgv7083n54	Chr.2:130236250 - 130440530 on Build GRCh38	Loss	CYP4F62P IMP4 PTPN18 CCDC115 FAR2P2
esv3592451	Chr.2:130282861 - 130401532 on Build GRCh38	Gain	IMP4 PTPN18 CCDC115
nsv583132	Chr.2:130255764 - 130390535 on Build GRCh38	Gain	IMP4 PTPN18 CCDC115
esv2751826	Chr.2:129606158 - 130385563 on Build GRCh38	Gain	MED15P9 LOC389033 FAR2P1 TUBA3E POTEF NOC2LP1 MZT2B SMPD4 LOC101927924 IMP4 PTPN18 RAB6C CCDC115 RAB6C-AS1 CCDC74B
nsv1001073	Chr.2:130290533 - 130400286 on Build GRCh38	Gain	IMP4 PTPN18 CCDC115
esv2759092	Chr.2:129589265 - 132440430 on Build GRCh38	Gain+Loss	CCDC74A GPR39 LOC100507460 POTEF MIR663B NOC2LP1 MZT2A AMER3 ZNF806 MZT2B LOC150776 LOC101927924 PTPN18 FAM168B CCDC74B MIR4784 MED15P9 POTEJ C2orf27B LOC440910 POTEI SMPD4 CFC1 FAM201B CYP4F62P LOC107985778 WTH3DI PLEKHB2 ANKRD30BL LINC01120 NOC2LP2 POTEKP TUBA3D CCDC115 LOC389033 CYP4F30P C2orf27A ARHGEF4 FAR2P1 TUBA3E CFC1B GPR148 POTEE IMP4 LOC646743 RAB6C RAB6C-AS1 LINC01087 TISP43 FAR2P2
esv3893326	Chr.2:130080351 - 130492798 on Build GRCh38	Gain	MED15P9 CYP4F62P POTEI TUBA3E POTEF NOC2LP1 MZT2B SMPD4 IMP4 PTPN18 CCDC115 CCDC74B FAR2P2
dgv4073n100	Chr.2:130091652 - 130400286 on Build GRCh38	Gain	NOC2LP1 MED15P9 MZT2B SMPD4 IMP4 TUBA3E POTEF PTPN18 CCDC115 CCDC74B
nsv428403	Chr.2:129818076 - 130882067 on Build GRCh38	Loss	CYP4F62P LOC107985778 POTEF NOC2LP1 AMER3 MZT2B LOC101927924 PTPN18 CCDC115 CCDC74B MED15P9 POTEJ LOC389033 CYP4F30P POTEI ARHGEF4 FAR2P1 TUBA3E CFC1B GPR148 SMPD4 CFC1 IMP4 LOC646743 RAB6C RAB6C-AS1 TISP43 FAR2P2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

protein dephosphorylation
peptidyl-tyrosine dephosphorylation

Function(s)

non-membrane spanning protein tyrosine phosphatase activity
protein binding