Hs00739439_cn

• Gene Symbol: PTPN18
• Assay Reference Genome Location: Chr.2:130358953 on build GRCh38
• Cytoband: 2q21.1

Target Gene Details

• Entrez Gene ID: 26469
• Gene Name: protein tyrosine phosphatase, non-receptor type 18
• Gene Aliases: BDP1, PTP-HSCF
• Location: Chr.2:130356007-130375409 on Build GRCh38
• Assay Gene Location: Overlaps Exon 2 - Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTPN18	NM_001142370.1			NP_001135842.1
	NM_014369.3			NP_055184.2
	XM_006712416.3			XP_006712479.1
	XM_006712417.1			XP_006712480.1
	XM_017003798.1			XP_016859287.1
	AK303804.1
	BC024280.1			AAH24280.1
	BC041562.1			AAH41562.1
	BC052800.1			AAH52800.1
	BI261717.1
	DN995571.1
	X79568.1			CAA56105.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv998333	Chr.2:130059754 - 130454126 on Build GRCh38	Gain+Loss	NOC2LP1 CCDC115 MZT2B CCDC74B SMPD4 FAR2P2 IMP4 TUBA3E CYP4F62P POTEF MED15P9 PTPN18
nsv459341	Chr.2:130281566 - 130390535 on Build GRCh38	Loss	CCDC115 IMP4 PTPN18
esv2760631	Chr.2:130005319 - 130400286 on Build GRCh38	Gain+Loss	NOC2LP1 CCDC115 MZT2B CCDC74B SMPD4 IMP4 TUBA3E POTEF FAR2P1 MED15P9 PTPN18
dgv7079n54	Chr.2:130181715 - 130391244 on Build GRCh38	Loss	NOC2LP1 CCDC115 MZT2B SMPD4 IMP4 TUBA3E PTPN18
nsv583113	Chr.2:130132813 - 130369588 on Build GRCh38	Gain	NOC2LP1 CCDC115 MZT2B CCDC74B SMPD4 IMP4 TUBA3E MED15P9 PTPN18
esv3584065	Chr.2:130046530 - 130400286 on Build GRCh38	Loss	NOC2LP1 CCDC115 MZT2B CCDC74B SMPD4 IMP4 TUBA3E POTEF FAR2P1 MED15P9 PTPN18
nsv520559	Chr.2:130133334 - 130390535 on Build GRCh38	Gain+Loss	NOC2LP1 CCDC115 MZT2B CCDC74B SMPD4 IMP4 TUBA3E MED15P9 PTPN18
nsv1005664	Chr.2:130159287 - 130649604 on Build GRCh38	Loss	NOC2LP1 CCDC115 MZT2B LOC646743 FAR2P2 IMP4 CFC1B CYP4F62P PTPN18 POTEJ SMPD4 LOC107985778 TISP43 POTEI TUBA3E CFC1
esv2763387	Chr.2:130026123 - 130400286 on Build GRCh38	Loss	NOC2LP1 CCDC115 MZT2B CCDC74B SMPD4 IMP4 TUBA3E POTEF FAR2P1 MED15P9 PTPN18
dgv475n27	Chr.2:130185940 - 130390535 on Build GRCh38	Gain	NOC2LP1 CCDC115 MZT2B IMP4 TUBA3E PTPN18
dgv7083n54	Chr.2:130236250 - 130440530 on Build GRCh38	Loss	CCDC115 FAR2P2 IMP4 CYP4F62P PTPN18
nsv583046	Chr.2:128746961 - 130390535 on Build GRCh38	Loss	NOC2LP1 CCDC115 MZT2B CCDC74B IMP4 RAB6C-AS1 LOC101927881 MED15P9 PTPN18 LOC151121 LOC101927924 SMPD4 RAB6C TUBA3E LOC389033 POTEF FAR2P1
esv3592450	Chr.2:130282861 - 130401532 on Build GRCh38	Loss	CCDC115 IMP4 PTPN18
nsv583132	Chr.2:130255764 - 130390535 on Build GRCh38	Gain	CCDC115 IMP4 PTPN18
nsv1001073	Chr.2:130290533 - 130400286 on Build GRCh38	Gain	CCDC115 IMP4 PTPN18
esv2751826	Chr.2:129606158 - 130385563 on Build GRCh38	Gain	NOC2LP1 CCDC115 MZT2B CCDC74B IMP4 RAB6C-AS1 MED15P9 PTPN18 LOC101927924 SMPD4 RAB6C TUBA3E LOC389033 POTEF FAR2P1
esv2759092	Chr.2:129589265 - 132440430 on Build GRCh38	Gain+Loss	IMP4 RAB6C-AS1 MED15P9 LOC101927924 LOC107985778 NOC2LP2 POTEI POTEF NOC2LP1 MZT2B FAR2P2 FAM168B CYP4F62P MIR663B POTEJ POTEKP LOC100507460 MZT2A TISP43 POTEE PLEKHB2 GPR39 FAR2P1 CYP4F30P FAM201B PTPN18 C2orf27A SMPD4 CFC1 LOC389033 CCDC115 LINC01087 CCDC74B LOC646743 MIR4784 LINC01120 CFC1B ANKRD30BL AMER3 CCDC74A ZNF806 ARHGEF4 GPR148 TUBA3D WTH3DI RAB6C LOC440910 TUBA3E C2orf27B LOC150776
dgv4073n100	Chr.2:130091652 - 130400286 on Build GRCh38	Gain	NOC2LP1 CCDC115 MZT2B CCDC74B SMPD4 IMP4 TUBA3E POTEF MED15P9 PTPN18
esv3893326	Chr.2:130080351 - 130492798 on Build GRCh38	Gain	NOC2LP1 CCDC115 MZT2B CCDC74B FAR2P2 IMP4 CYP4F62P MED15P9 PTPN18 SMPD4 POTEI TUBA3E POTEF
nsv428403	Chr.2:129818076 - 130882067 on Build GRCh38	Loss	CYP4F30P IMP4 RAB6C-AS1 MED15P9 PTPN18 LOC101927924 SMPD4 LOC107985778 POTEI CFC1 LOC389033 POTEF NOC2LP1 CCDC115 MZT2B CCDC74B LOC646743 FAR2P2 CFC1B AMER3 CYP4F62P ARHGEF4 POTEJ GPR148 TISP43 RAB6C TUBA3E FAR2P1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

protein dephosphorylation
peptidyl-tyrosine dephosphorylation

Function(s)

non-membrane spanning protein tyrosine phosphatase activity
protein binding