Hs00743583_cn

• Gene Symbol: FSTL3
• Assay Reference Genome Location: Chr.19:681340 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 10272
• Gene Name: follistatin like 3
• Gene Aliases: FLRG, FSRP
• Location: Chr.19:676389-683392 on Build GRCh38
• Assay Gene Location: Overlaps Intron 3 - Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FSTL3	NM_005860.2			NP_005851.1
	AK291958.1
	AK311521.1
	AK311566.1
	AK313341.1
	AY358917.1			AAQ89276.1
	BC005839.2			AAH05839.1
	BX439786.2
	U76702.1			AAC64321.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv578163	Chr.19:629303 - 682010 on Build GRCh38	Loss	FSTL3 POLRMT RNF126 FGF22
dgv134n111	Chr.19:607984 - 967584 on Build GRCh38	Deletion	PRSS57 CFD ELANE LOC101928450 KISS1R PALM RNU6-9 MISP PLPPR3 PRTN3 FSTL3 POLRMT R3HDM4 HCN2 AZU1 MED16 PTBP1 MIR3187 RNF126 ARID3A FGF22 MIR4745
nsv428360	Chr.19:232069 - 702131 on Build GRCh38	Gain	PRSS57 GZMM TPGS1 MIER2 BSG LOC101929060 PLPP2 ODF3L2 SHC2 MADCAM1 FSTL3 POLRMT HCN2 THEG CDC34 C2CD4C RNF126 FGF22
nsv577978	Chr.19:294526 - 782854 on Build GRCh38	Gain	PRSS57 GZMM LOC101928450 TPGS1 MIER2 PALM MISP BSG LOC101929060 ODF3L2 SHC2 MADCAM1 FSTL3 POLRMT HCN2 THEG CDC34 C2CD4C RNF126 FGF22
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	PRSS57 GRIN3B ELANE PALM MISP BSG ARHGAP45 ABCA7 R3HDM4 HCN2 AZU1 THEG MED16 PTBP1 MIR3187 ARID3A POLR2E CFD GZMM LOC105372235 LOC101928450 TPGS1 TMEM259 KISS1R RNU6-9 PLPPR3 PRTN3 ODF3L2 SHC2 CNN2 WDR18 MADCAM1 FSTL3 POLRMT GPX4 CDC34 RNU6-2 C2CD4C RNF126 FGF22 MIR4745
nsv470101	Chr.19:401714 - 1008505 on Build GRCh38	Loss	PRSS57 GRIN3B ELANE PALM MISP BSG R3HDM4 HCN2 AZU1 MED16 PTBP1 MIR3187 ARID3A CFD GZMM LOC105372235 LOC101928450 TPGS1 KISS1R RNU6-9 PLPPR3 PRTN3 ODF3L2 SHC2 WDR18 MADCAM1 FSTL3 POLRMT CDC34 C2CD4C RNF126 FGF22 MIR4745

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

extracellular matrix glycoprotein

Gene Ontology Categories:

Process(es)

ossification
kidney development
hematopoietic progenitor cell differentiation
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
spermatogenesis
male gonad development
positive regulation of cell-cell adhesion
lung development
adrenal gland development
negative regulation of BMP signaling pathway
negative regulation of activin receptor signaling pathway
negative regulation of osteoclast differentiation
positive regulation of transcription from RNA polymerase II promoter
cellular response to metal ion
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

Function(s)

fibronectin binding
protein binding
activin binding