Hs00753254_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137180869 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Within Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3	8	1602	NP_037498.1
	AB037827.1	6	778	BAA92644.1
	AF191337.1	8	1529	AAF05751.1
	AK294601.1	8	1557
	BC001579.1	6	794	AAH01579.1
	BC009487.2	4	393	AAH09487.2
	BC032503.1	8	1534	AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	GRIN1 MAN1B1 LOC101930307 ANAPC2 DPP7 SSNA1 TMEM210 RNF208 CYSRT1 NDOR1 LRRC26 MAN1B1-AS1 RNF224 TMEM203 TPRN UAP1L1 MIR3621 SLC34A3
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	TUBB4B NELFB ANAPC2 SSNA1 C9orf173-AS1 RNF208 EXD3 CYSRT1 STPG3 NDOR1 TOR4A RNF224 TMEM203 TPRN FAM166A SLC34A3 NRARP
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	CCDC183-AS1 CLIC3 MAN1B1 NELFB FUT7 TRAF2 ANAPC2 PRR31 LCNL1 PHPT1 FBXW5 CCDC183 MIR3621 PTGDS C9orf142 NPDC1 TMEM210 RNF208 SAPCD2 ABCA2 TOR4A MAN1B1-AS1 C8G C9orf139 RNF224 MIR4479 PNPLA7 SLC34A3 TUBB4B MIR4292 NOXA1 LOC101930307 SSNA1 EXD3 MAMDC4 CYSRT1 STPG3 NDOR1 LRRC26 EDF1 ENTPD2 TMEM203 RABL6 TPRN FAM166A GRIN1 NSMF C9orf172 ENTPD8 DPP7 C9orf173-AS1 MIR7114 UAP1L1 LCN12 NRARP
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	TUBB4B GRIN1 NELFB ANAPC2 SSNA1 C9orf173-AS1 TMEM210 RNF208 EXD3 CYSRT1 STPG3 NDOR1 TOR4A LRRC26 RNF224 TMEM203 TPRN FAM166A MIR3621 SLC34A3 NRARP
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	GRIN1 MAN1B1 LOC101930307 FUT7 ANAPC2 DPP7 SSNA1 NPDC1 TMEM210 SAPCD2 LRRC26 MAN1B1-AS1 C9orf139 ENTPD2 UAP1L1 MIR3621
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	TUBB4B GRIN1 NOXA1 NELFB ENTPD8 ANAPC2 SSNA1 C9orf173-AS1 TMEM210 RNF208 EXD3 CYSRT1 STPG3 NDOR1 TOR4A LRRC26 RNF224 TMEM203 TPRN FAM166A MIR3621 SLC34A3 NRARP
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	CCDC183-AS1 CLIC3 MAN1B1 NELFB FUT7 TRAF2 ANAPC2 PRR31 LCNL1 SNORA17B PHPT1 FBXW5 LCN15 CCDC183 MIR3621 LINC01451 PTGDS C9orf142 AGPAT2 SNORA17A NPDC1 TMEM210 RNF208 SAPCD2 ABCA2 LCN8 TOR4A MAN1B1-AS1 C8G C9orf139 RNF224 MIR4479 MIR126 LCN10 SLC34A3 TUBB4B MIR4292 HSPC324 LOC101930307 SSNA1 EXD3 MAMDC4 CYSRT1 STPG3 LOC100128593 NDOR1 LRRC26 EDF1 ENTPD2 TMEM203 RABL6 TPRN FAM166A TMEM141 SNHG7 MIR6722 GRIN1 C9orf172 DPP7 LCN6 C9orf173-AS1 FAM69B UAP1L1 EGFL7 LCN12 NRARP

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity