Hs00778076_cn

• Gene Symbol: UBE2O
• Assay Reference Genome Location: Chr.17:76390243 on build GRCh38
• Cytoband: 17q25.1

Target Gene Details

• Entrez Gene ID: 63893
• Gene Name: ubiquitin conjugating enzyme E2 O
• Gene Aliases: E2-230K
• Location: Chr.17:76389532-76453206 on Build GRCh38
• Assay Gene Location: Within Exon 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
UBE2O	NM_022066.3	18	4644	NP_071349.3
	XM_005257567.1	18	4631	XP_005257624.1
	XM_017024934.1	18	4556	XP_016880423.1
	XM_017024935.1	18	4553	XP_016880424.1
	AB051521.1	18	4644
	AK000926.1	1	879
	AK022940.1	5	2142	BAB14320.1
	AK024657.1	3	1643	BAB14948.1
	AK025999.1	10	3123	BAB15313.1
	AL832432.1	11	3569	CAH10644.1
	BC004525.2	3	1459	AAH04525.2
	BC022237.1	5	2162	AAH22237.1
	BC025977.1	5	2043	AAH25977.1
	BC036820.1	13	3780	AAH36820.1
	BC051868.2	10	2987	AAH51868.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv2145	Chr.17:76363105 - 76408339 on Build GRCh38	Deletion	UBE2O SPHK1
nsv833547	Chr.17:76208499 - 76399227 on Build GRCh38	Loss	PRPSAP1 UBE2O UBALD2 RNF157 QRICH2 SPHK1
nsv833549	Chr.17:76365444 - 76527890 on Build GRCh38	Gain	CYGB UBE2O RHBDF2 SPHK1 PRCD AANAT

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

protein monoubiquitination
positive regulation of BMP signaling pathway
retrograde transport, endosome to Golgi
protein K63-linked ubiquitination

Function(s)

ubiquitin-protein transferase activity
protein binding
ATP binding
ubiquitin protein ligase binding
poly(A) RNA binding
ubiquitin protein ligase activity
ubiquitin conjugating enzyme activity