Hs00795946_cn

• Gene Symbol: PLPPR3
• Assay Reference Genome Location: Chr.19:814493 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 79948
• Gene Name: phospholipid phosphatase related 3
• Gene Aliases: LPPR3, LPR3, PRG-2, PRG2
• Location: Chr.19:812488-824244 on Build GRCh38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PLPPR3	NM_001270366.1	7	836	NP_001257295.1
	NM_024888.2	6	920	NP_079164.1
	XM_011528317.2	6	1512	XP_011526619.1
	AF357888.1	6	1183	AAO85401.1
	AF541282.1	6	920	AAP57771.1
	AK021597.1	2	167	BAB13851.1
	AL136596.1	6	920	CAB66531.1
	AY304517.1	6	920	AAP72154.1
	AY436785.1	7	835	AAR10818.1
	BC012339.1	4	428	AAH12339.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv134n111	Chr.19:607984 - 967584 on Build GRCh38	Deletion	POLRMT MISP PTBP1 R3HDM4 MED16 RNU6-9 PRSS57 FGF22 ELANE PRTN3 LOC101928450 PALM RNF126 MIR3187 CFD FSTL3 PLPPR3 ARID3A KISS1R AZU1 MIR4745 HCN2
nsv578172	Chr.19:811414 - 841398 on Build GRCh38	Loss	MIR3187 PTBP1 PRTN3 PLPPR3 AZU1
nsv578167	Chr.19:797079 - 850574 on Build GRCh38	Loss	MIR3187 PTBP1 PRTN3 PLPPR3 AZU1 MIR4745
nsv828354	Chr.19:796933 - 815173 on Build GRCh38	Gain	MIR3187 PTBP1 PLPPR3 MIR4745
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	MISP ARHGAP45 R3HDM4 MED16 PRSS57 FGF22 POLR2E ELANE PRTN3 GZMM C2CD4C BSG CDC34 GRIN3B FSTL3 RNU6-2 TPGS1 PLPPR3 KISS1R AZU1 WDR18 POLRMT PTBP1 ODF3L2 RNU6-9 LOC101928450 PALM MADCAM1 CNN2 RNF126 MIR3187 SHC2 GPX4 CFD ABCA7 THEG ARID3A MIR4745 TMEM259 LOC105372235 HCN2
nsv470101	Chr.19:401714 - 1008505 on Build GRCh38	Loss	MISP R3HDM4 MED16 PRSS57 FGF22 ELANE PRTN3 GZMM C2CD4C BSG CDC34 GRIN3B FSTL3 TPGS1 PLPPR3 KISS1R AZU1 WDR18 POLRMT PTBP1 ODF3L2 RNU6-9 LOC101928450 PALM MADCAM1 RNF126 MIR3187 SHC2 CFD ARID3A MIR4745 LOC105372235 HCN2

More Information

Additional Information:

For this assay, SNP(s) [rs76900321] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphatase

Gene Ontology Categories:

Process(es)

phospholipid metabolic process
signal transduction
phospholipid dephosphorylation

Function(s)

phosphatidate phosphatase activity
lipid phosphatase activity