Hs00838440_cn

• Gene Symbol: CHMP2A
• Assay Reference Genome Location: Chr.19:58551741 on build GRCh38
• Cytoband: 19q13.43

Target Gene Details

• Entrez Gene ID: 27243
• Gene Name: charged multivesicular body protein 2A
• Gene Aliases: BC-2, BC2, CHMP2, VPS2, VPS2A
• Location: Chr.19:58551566-58555624 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CHMP2A	NM_014453.3			NP_055268.1
	NM_198426.2			NP_940818.1
	XM_005258746.2	5	1367	XP_005258803.1
	XM_005258747.3	5	1490	XP_005258804.1
	AF042384.1			AAC00005.1
	AK311974.1
	AY364248.1			AAQ76807.1
	BC002502.2			AAH02502.1
	BE856471.1
	BG546479.1
	BI457978.1
	BT007298.1			AAP35962.1
	BU147101.1
	CR457002.1			CAG33283.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1057206	Chr.19:58546716 - 58586475 on Build GRCh38	Gain	MIR6807 CHMP2A UBE2M CENPBD1P1 TRIM28 MZF1 MZF1-AS1
dgv3687n100	Chr.19:58473466 - 58586475 on Build GRCh38	Gain	MIR6807 CHMP2A UBE2M CENPBD1P1 SLC27A5 TRIM28 ZNF324 MZF1 MZF1-AS1 ZNF446 ZBTB45
nsv515731	Chr.19:58320453 - 58576112 on Build GRCh38	Gain+Loss	UBE2M CENPBD1P1 TRIM28 LOC105372483 MZF1 ZNF446 ZNF584 A1BG-AS1 LOC100419840 MIR6807 SLC27A5 ZSCAN22 ZNF324 RPS5 CHMP2A ZNF132 LOC100506634 ZNF497 A1BG MIR6806 ZNF324B MIR4754 MZF1-AS1 RNF225 ZNF837 ZBTB45
nsv952156	Chr.19:58466134 - 58600733 on Build GRCh38	Deletion	MIR6807 CHMP2A UBE2M CENPBD1P1 SLC27A5 TRIM28 ZNF324 MZF1 MZF1-AS1 ZNF446 ZBTB45
nsv1160670	Chr.19:58433008 - 58586487 on Build GRCh38	Deletion	CHMP2A UBE2M CENPBD1P1 TRIM28 MZF1 ZNF446 ZNF132 ZNF324B MIR6807 SLC27A5 ZNF324 MZF1-AS1 ZBTB45
nsv828657	Chr.19:58483484 - 58585740 on Build GRCh38	Gain	MIR6807 CHMP2A UBE2M CENPBD1P1 SLC27A5 TRIM28 MZF1 MZF1-AS1 ZNF446 ZBTB45
dgv3688n100	Chr.19:58506055 - 58586475 on Build GRCh38	Gain	MIR6807 CHMP2A UBE2M CENPBD1P1 SLC27A5 TRIM28 MZF1 MZF1-AS1 ZBTB45
nsv1057077	Chr.19:58411953 - 58586475 on Build GRCh38	Gain	CHMP2A UBE2M CENPBD1P1 TRIM28 MZF1 ZNF446 ZNF132 ZNF584 ZNF324B MIR6807 SLC27A5 ZNF324 MZF1-AS1 ZBTB45

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane traffic protein

Gene Ontology Categories:

Process(es)

cell separation after cytokinesis
autophagy
nucleus organization
mitotic metaphase plate congression
membrane invagination
exit from mitosis
regulation of centrosome duplication
protein transport
endosomal transport
viral life cycle
nuclear envelope reassembly
multivesicular body assembly
viral budding via host ESCRT complex
establishment of protein localization
regulation of viral process
protein polymerization
protein homooligomerization
protein heterooligomerization
negative regulation of cell death
regulation of mitotic spindle assembly
positive regulation of viral release from host cell
positive regulation of exosomal secretion
negative regulation of centriole elongation
ESCRT III complex disassembly

Function(s)

protein binding
protein domain specific binding
phosphatidylcholine binding