Hs00848247_cn

• Gene Symbol: SENP1
• Assay Reference Genome Location: Chr.12:48043132 on build GRCh38
• Cytoband: 12q13.11

Target Gene Details

• Entrez Gene ID: 29843
• Gene Name: SUMO1/sentrin specific peptidase 1
• Gene Aliases: SuPr-2
• Location: Chr.12:48042893-48106308 on Build GRCh38
• Assay Gene Location: Within Exon 21

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SENP1	NM_001267594.1	18	4450	NP_001254523.1
	NM_001267595.1	18	4705	NP_001254524.1
	NR_051991.1	19	4891
	NR_051992.1	19	4904
	XM_006719362.2	19	4357	XP_006719425.1
	XM_017019236.1	17	4511	XP_016874725.1
	XM_017019237.1	17	4411	XP_016874726.1
	BX640784.1	19	4735	CAE45874.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759898	Chr.12:48035919 - 48431716 on Build GRCh38	Gain+Loss	C12orf54 OR10AD1 MIR6505 SENP1 ZNF641 PFKM H1FNT ASB8 CCDC184
nsv832401	Chr.12:47953670 - 48084216 on Build GRCh38	Loss	COL2A1 TMEM106C SENP1 LOC105369750

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

proteolysis
activation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of definitive erythrocyte differentiation
protein sumoylation
protein desumoylation
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of transcription from RNA polymerase II promoter
apoptotic signaling pathway

Function(s)

endopeptidase activity
protein binding
SUMO-specific protease activity
SUMO-specific endopeptidase activity