Hs00851796_cn

• Gene Symbol: DUOX1
• Assay Reference Genome Location: Chr.15:45142032 on build GRCh38
• Cytoband: 15q21.1

Target Gene Details

• Entrez Gene ID: 53905
• Gene Name: dual oxidase 1
• Gene Aliases: LNOX1, NOXEF1, THOX1
• Location: Chr.15:45129994-45165578 on Build GRCh38
• Assay Gene Location: Within Exon 16

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DUOX1	NM_017434.4	16	2088	NP_059130.2
	NM_175940.2	15	1896	NP_787954.1
	XM_011521681.2	14	1789	XP_011519983.1
	XM_011521682.1	5	699	XP_011519984.1
	AF213465.1	15	1896	AAF71295.1
	AF230495.1	16	2088	AAF73921.1
	AK075268.1	15	1897
	AK128591.1	5	953
	AK290372.1	16	2149
	BC114628.1	15	1885
	BC114938.1	15	1885

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv518213	Chr.15:45129560 - 45172570 on Build GRCh38	Gain	SHF DUOXA1 DUOX1
nsv569312	Chr.15:45089800 - 45168224 on Build GRCh38	Loss	DUOXA2 SHF DUOX2 DUOXA1 DUOX1
nsv457125	Chr.15:45128520 - 45158125 on Build GRCh38	Loss	DUOXA1 DUOX1
nsv569313	Chr.15:45121343 - 45165260 on Build GRCh38	Gain	DUOXA1 DUOX1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidase

Gene Ontology Categories:

Process(es)

thyroid hormone generation
response to oxidative stress
cytokine-mediated signaling pathway
cuticle development
hormone biosynthetic process
superoxide anion generation
hydrogen peroxide catabolic process
hydrogen peroxide biosynthetic process
response to cAMP
oxidation-reduction process
cellular oxidant detoxification

Function(s)

peroxidase activity
calcium ion binding
NAD(P)H oxidase activity
heme binding
NADP binding