Hs00872354_cn

• Gene Symbol: MRM2
• Assay Reference Genome Location: Chr.7:2239429 on build GRCh38
• Cytoband: 7p22.3

Target Gene Details

• Entrez Gene ID: 29960
• Gene Name: mitochondrial rRNA methyltransferase 2
• Gene Aliases: FJH1, FTSJ2, HEL97, RRMJ2
• Location: Chr.7:2234291-2242198 on Build GRCh38
• Assay Gene Location: Overlaps Intron 2 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MRM2	NM_013393.1			NP_037525.1
	AF093415.1			AAF22488.1
	AK302060.1
	BC114514.1			AAI14515.1
	BC114564.1			AAI14565.1
	CR749618.1			CAH18412.1
	EU794658.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1021310	Chr.7:1936627 - 2280155 on Build GRCh38	Loss	NUDT1 MIR6836 MRM2 SNX8 MAD1L1
nsv1018563	Chr.7:2233301 - 2325297 on Build GRCh38	Gain	NUDT1 MIR6836 MRM2 SNX8
nsv1021173	Chr.7:2206456 - 2334992 on Build GRCh38	Loss	NUDT1 MIR6836 MRM2 SNX8 MAD1L1
nsv830886	Chr.7:2145358 - 2337903 on Build GRCh38	Loss	NUDT1 MIR6836 MRM2 SNX8 MAD1L1
esv2761136	Chr.7:2230260 - 2325309 on Build GRCh38	Gain	NUDT1 MIR6836 MRM2 SNX8 MAD1L1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA metabolism protein, RNA methyltransferase, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

enzyme-directed rRNA 2'-O-methylation
rRNA processing
cell proliferation
rRNA methylation

Function(s)

rRNA (uridine-2'-O-)-methyltransferase activity