Hs00925695_cn

• Gene Symbol: HES6
• Assay Reference Genome Location: Chr.2:238238350 on build GRCh38
• Cytoband: 2q37.3

Target Gene Details

• Entrez Gene ID: 55502
• Gene Name: hes family bHLH transcription factor 6
• Gene Aliases: C-HAIRY1, HES-6, bHLHb41, bHLHc23
• Location: Chr.2:238238267-238240124 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HES6	NM_001142853.2	4	1365	NP_001136325.1
	NM_001282434.1	4	1331	NP_001269363.1
	NM_018645.5	4	1371	NP_061115.2
	AF260237.1	4	1212	AAK51634.1
	AK075040.1	3	1520	BAC11368.1
	BC007939.2	4	1276	AAH07939.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv584761	Chr.2:238212011 - 238246412 on Build GRCh38	Gain	LOC643387 HES6 LOC101927958 LOC151174 PER2
nsv1000252	Chr.2:235899999 - 238766417 on Build GRCh38	Loss	UBE2F AGAP1 ASB18 LOC105373991 LOC105373958 MLPH KLHL30 LOC93463 LINC01107 IQCA1 MIR6811 ESPNL ACKR3 LRRFIP1 PER2 ASB1 ILKAP UBE2F-SCLY RBM44 LOC643387 SCLY COPS8 RAMP1 LOC101927958 PRLH COL6A3 GBX2 HES6 TRAF3IP1 LOC105373944 ERFE LOC151174 RAB17
dgv7349n54	Chr.2:238238228 - 238241307 on Build GRCh38	Loss	HES6

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
nervous system development
cell differentiation

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription cofactor activity
transcription factor binding
protein dimerization activity