Hs00943121_cn

• Gene Symbol: EXOC3
• Assay Reference Genome Location: Chr.5:446273 on build GRCh38
• Cytoband: 5p15.33

Target Gene Details

• Entrez Gene ID: 11336
• Gene Name: exocyst complex component 3
• Gene Aliases: SEC6, SEC6L1, Sec6p
• Location: Chr.5:443184-471938 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXOC3	NM_007277.4	2	196	NP_009208.2
	XM_011513948.2	2	231	XP_011512250.1
	XM_011513949.2	2	248	XP_011512251.1
	XM_011513950.2	1	126	XP_011512252.1
	XM_011513951.2	2	225	XP_011512253.1
	XM_017009000.1	2	231	XP_016864489.1
	XM_017009001.1	2	231	XP_016864490.1
	XM_017009002.1	2	231	XP_016864491.1
	XM_017009003.1	2	231	XP_016864492.1
	XM_017009004.1	3	309	XP_016864493.1
	XM_017009005.1	2	225	XP_016864494.1
	XM_017009006.1	2	225	XP_016864495.1
	AK074086.1	1	187	BAB84912.1
	AL545132.3	2	229
	BC064569.1	1	138	AAH64569.1
	GU727644.1	2	196

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3894107	Chr.5:81322 - 801057 on Build GRCh38	Gain	CCDC127 PLEKHG4B SLC9A3 CEP72 LOC101929895 PDCD6 LRRC14B EXOC3-AS1 ZDHHC11B AHRR LOC100996325 PP7080 LOC100288152 ZDHHC11 TPPP HRAT5 MIR4456 EXOC3 SDHA
nsv830183	Chr.5:349237 - 502409 on Build GRCh38	Gain+Loss	PP7080 LOC100288152 SLC9A3 EXOC3-AS1 EXOC3 AHRR
nsv1032584	Chr.5:375290 - 809679 on Build GRCh38	Gain	SLC9A3 CEP72 LOC101929895 EXOC3-AS1 ZDHHC11B AHRR LOC100996325 PP7080 LOC100288152 ZDHHC11 TPPP MIR4456 EXOC3
nsv461889	Chr.5:429874 - 598109 on Build GRCh38	Gain	PP7080 LOC100288152 SLC9A3 EXOC3-AS1 MIR4456 EXOC3 AHRR
nsv1030767	Chr.5:154674 - 457840 on Build GRCh38	Gain	CCDC127 PLEKHG4B HRAT5 PDCD6 LRRC14B EXOC3-AS1 EXOC3 SDHA AHRR
dgv9479n54	Chr.5:438449 - 567131 on Build GRCh38	Gain	PP7080 LOC100288152 SLC9A3 EXOC3-AS1 MIR4456 EXOC3
esv2759315	Chr.5:17263 - 595840 on Build GRCh38	Loss	CCDC127 PLEKHG4B SLC9A3 PDCD6 LRRC14B EXOC3-AS1 AHRR PP7080 LOC100288152 HRAT5 MIR4456 EXOC3 SDHA
nsv1032824	Chr.5:335214 - 449516 on Build GRCh38	Gain	EXOC3-AS1 EXOC3 AHRR
esv3603744	Chr.5:359572 - 478120 on Build GRCh38	Gain	PP7080 LOC100288152 SLC9A3 EXOC3-AS1 EXOC3 AHRR
nsv4673	Chr.5:414170 - 449449 on Build GRCh38	Insertion	EXOC3-AS1 EXOC3 AHRR
nsv1027279	Chr.5:337575 - 531110 on Build GRCh38	Gain	PP7080 LOC100288152 SLC9A3 EXOC3-AS1 EXOC3 AHRR
nsv1019215	Chr.5:346521 - 661696 on Build GRCh38	Gain	PP7080 LOC100288152 SLC9A3 CEP72 TPPP EXOC3-AS1 MIR4456 EXOC3 AHRR LOC100996325
esv2752071	Chr.5:378298 - 699075 on Build GRCh38	Gain	PP7080 LOC100288152 SLC9A3 CEP72 LOC101929895 TPPP EXOC3-AS1 MIR4456 EXOC3 AHRR LOC100996325
nsv830184	Chr.5:378153 - 451752 on Build GRCh38	Gain	EXOC3-AS1 EXOC3 AHRR
esv3603745	Chr.5:376684 - 458243 on Build GRCh38	Gain	EXOC3-AS1 EXOC3 AHRR

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane traffic protein

Gene Ontology Categories:

Process(es)

exocytosis
protein transport
exocyst localization
cell-cell adhesion

Function(s)

SNARE binding
protein binding
cadherin binding involved in cell-cell adhesion