Hs00958839_cn

• Gene Symbol: PTPN18
• Assay Reference Genome Location: Chr.2:130359249 on build GRCh38
• Cytoband: 2q21.1

Target Gene Details

• Entrez Gene ID: 26469
• Gene Name: protein tyrosine phosphatase, non-receptor type 18
• Gene Aliases: BDP1, PTP-HSCF
• Location: Chr.2:130356007-130375409 on Build GRCh38
• Assay Gene Location: Overlaps Intron 2 - Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTPN18	NM_001142370.1			NP_001135842.1
	NM_014369.3			NP_055184.2
	XM_006712416.3			XP_006712479.1
	XM_006712417.1			XP_006712480.1
	XM_017003798.1			XP_016859287.1
	AK303804.1
	BC024280.1			AAH24280.1
	BC041562.1			AAH41562.1
	BC052800.1			AAH52800.1
	BI261717.1
	DN995571.1
	X79568.1			CAA56105.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv998333	Chr.2:130059754 - 130454126 on Build GRCh38	Gain+Loss	CCDC115 NOC2LP1 FAR2P2 CYP4F62P SMPD4 MZT2B PTPN18 TUBA3E CCDC74B IMP4 MED15P9 POTEF
esv2760631	Chr.2:130005319 - 130400286 on Build GRCh38	Gain+Loss	CCDC115 NOC2LP1 FAR2P1 SMPD4 MZT2B PTPN18 TUBA3E CCDC74B IMP4 MED15P9 POTEF
nsv583133	Chr.2:130281566 - 130390535 on Build GRCh38	Loss	CCDC115 PTPN18 IMP4
dgv7079n54	Chr.2:130181715 - 130391244 on Build GRCh38	Loss	CCDC115 NOC2LP1 SMPD4 MZT2B PTPN18 TUBA3E IMP4
esv3584065	Chr.2:130046530 - 130400286 on Build GRCh38	Loss	CCDC115 NOC2LP1 FAR2P1 SMPD4 MZT2B PTPN18 TUBA3E CCDC74B IMP4 MED15P9 POTEF
nsv583113	Chr.2:130132813 - 130369588 on Build GRCh38	Gain	CCDC115 NOC2LP1 SMPD4 MZT2B PTPN18 TUBA3E CCDC74B IMP4 MED15P9
nsv520559	Chr.2:130133334 - 130390535 on Build GRCh38	Gain+Loss	CCDC115 NOC2LP1 SMPD4 MZT2B PTPN18 TUBA3E CCDC74B IMP4 MED15P9
nsv1005664	Chr.2:130159287 - 130649604 on Build GRCh38	Loss	CCDC115 POTEJ FAR2P2 CFC1 CYP4F62P SMPD4 PTPN18 TUBA3E TISP43 POTEI NOC2LP1 LOC646743 CFC1B MZT2B IMP4 LOC107985778
esv2763387	Chr.2:130026123 - 130400286 on Build GRCh38	Loss	CCDC115 NOC2LP1 FAR2P1 SMPD4 MZT2B PTPN18 TUBA3E CCDC74B IMP4 MED15P9 POTEF
dgv7080n54	Chr.2:130185940 - 130390535 on Build GRCh38	Gain	CCDC115 NOC2LP1 MZT2B PTPN18 TUBA3E IMP4
nsv459274	Chr.2:128746961 - 130390535 on Build GRCh38	Loss	CCDC115 SMPD4 PTPN18 TUBA3E LOC101927924 MED15P9 RAB6C POTEF NOC2LP1 FAR2P1 LOC389033 LOC101927881 LOC151121 MZT2B CCDC74B IMP4 RAB6C-AS1
dgv7083n54	Chr.2:130236250 - 130440530 on Build GRCh38	Loss	CCDC115 FAR2P2 CYP4F62P PTPN18 IMP4
esv3592451	Chr.2:130282861 - 130401532 on Build GRCh38	Gain	CCDC115 PTPN18 IMP4
nsv583132	Chr.2:130255764 - 130390535 on Build GRCh38	Gain	CCDC115 PTPN18 IMP4
esv2751826	Chr.2:129606158 - 130385563 on Build GRCh38	Gain	CCDC115 SMPD4 PTPN18 TUBA3E LOC101927924 MED15P9 RAB6C POTEF NOC2LP1 FAR2P1 LOC389033 MZT2B CCDC74B IMP4 RAB6C-AS1
nsv1001073	Chr.2:130290533 - 130400286 on Build GRCh38	Gain	CCDC115 PTPN18 IMP4
esv2759092	Chr.2:129589265 - 132440430 on Build GRCh38	Gain+Loss	LOC440910 GPR39 POTEJ FAR2P2 CFC1 RAB6C ARHGEF4 LOC389033 CFC1B IMP4 RAB6C-AS1 SMPD4 FAM201B PTPN18 TUBA3D WTH3DI NOC2LP2 NOC2LP1 MZT2A FAM168B LOC646743 POTEKP CCDC74B LOC100507460 CCDC115 CCDC74A C2orf27B LOC150776 CYP4F62P C2orf27A TISP43 LOC101927924 MED15P9 MIR663B PLEKHB2 ANKRD30BL MIR4784 MZT2B LINC01087 LOC107985778 POTEE GPR148 CYP4F30P LINC01120 TUBA3E POTEF POTEI FAR2P1 ZNF806 AMER3
esv3893326	Chr.2:130080351 - 130492798 on Build GRCh38	Gain	CCDC115 FAR2P2 CYP4F62P SMPD4 PTPN18 TUBA3E MED15P9 POTEF POTEI NOC2LP1 MZT2B CCDC74B IMP4
dgv4073n100	Chr.2:130091652 - 130400286 on Build GRCh38	Gain	CCDC115 NOC2LP1 SMPD4 MZT2B PTPN18 TUBA3E CCDC74B IMP4 MED15P9 POTEF
nsv428403	Chr.2:129818076 - 130882067 on Build GRCh38	Loss	CCDC115 POTEJ FAR2P2 CFC1 CYP4F62P TISP43 LOC101927924 MED15P9 RAB6C ARHGEF4 LOC389033 CFC1B MZT2B IMP4 RAB6C-AS1 LOC107985778 GPR148 CYP4F30P SMPD4 PTPN18 TUBA3E POTEF POTEI NOC2LP1 FAR2P1 LOC646743 CCDC74B AMER3

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

protein dephosphorylation
peptidyl-tyrosine dephosphorylation

Function(s)

non-membrane spanning protein tyrosine phosphatase activity
protein binding