Hs00960428_cn

• Gene Symbol: PPP1R16A
• Assay Reference Genome Location: Chr.8:144497323 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 84988
• Gene Name: protein phosphatase 1 regulatory subunit 16A
• Gene Aliases: MYPT3
• Location: Chr.8:144477987-144502121 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPP1R16A	XM_005272350.2	3	1183	XP_005272407.1
	XM_011517349.2			XP_011515651.1
	XM_017013912.1	4	1252	XP_016869401.1
	XM_017013913.1	3	1216	XP_016869402.1
	XM_017013914.1	4	1290	XP_016869403.1
	XM_017013915.1	3	1247	XP_016869404.1
	AK090471.1			BAC03452.1
	BC007854.2	1	257	AAH07854.1
	BC049841.1	1	509	AAH49841.1
	BC053506.1	1	598	AAH53506.1
	BT006845.1	1	129	AAP35491.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	EXOSC4 LOC101928953 SCRT1 HSF1 SMPD5 PPP1R16A MIR6848 PLEC FOXH1 DGAT1 SHARPIN MROH1 MFSD3 VPS28 MIR6849 CYC1 WDR97 CYHR1 MIR6893 FBXL6 HGH1 BOP1 CPSF1 KIFC2 GPT TMEM249 SPATC1 PARP10 MIR6847 TONSL RECQL4 MIR661 GPAA1 MIR7112 OPLAH MIR1234 LRRC14 MIR6846 ADCK5 MAF1 SCX SLC52A2 GRINA SLC39A4 MIR939 TONSL-AS1 LOC101928902
nsv612951	Chr.8:144479830 - 144677692 on Build GRCh38	Loss	LOC101928953 ARHGAP39 C8orf82 RECQL4 PPP1R16A LRRC24 MFSD3 LRRC14 GPT
nsv831489	Chr.8:144342140 - 144544026 on Build GRCh38	Loss	LOC101928953 ARHGAP39 PPP1R16A FOXH1 MFSD3 VPS28 MIR6849 C8orf82 CYHR1 MIR6893 FBXL6 CPSF1 KIFC2 GPT TMEM249 TONSL RECQL4 LRRC24 MIR1234 LRRC14 ADCK5 SLC52A2 SLC39A4 MIR939 TONSL-AS1 LOC101928902
dgv12439n54	Chr.8:144438306 - 144525122 on Build GRCh38	Loss	LOC101928953 TONSL RECQL4 PPP1R16A CYHR1 FOXH1 TONSL-AS1 LRRC24 KIFC2 MFSD3 LRRC14 GPT
nsv612955	Chr.8:144494912 - 144502322 on Build GRCh38	Loss	LOC101928953 PPP1R16A GPT
nsv482126	Chr.8:144496726 - 144502120 on Build GRCh38	Gain	LOC101928953 PPP1R16A
dgv907n27	Chr.8:144416180 - 144525122 on Build GRCh38	Loss	LOC101928953 TONSL RECQL4 PPP1R16A FOXH1 LRRC24 MFSD3 LRRC14 VPS28 CYHR1 MIR6893 SLC39A4 TONSL-AS1 KIFC2 GPT
dgv12434n54	Chr.8:144270080 - 144516801 on Build GRCh38	Loss	LOC101928953 SCRT1 HSF1 PPP1R16A MIR6848 FOXH1 DGAT1 MFSD3 VPS28 MIR6849 CYHR1 MIR6893 FBXL6 BOP1 CPSF1 KIFC2 GPT TMEM249 TONSL RECQL4 MIR1234 ADCK5 SLC52A2 SLC39A4 MIR939 TONSL-AS1 LOC101928902
dgv12442n54	Chr.8:144492696 - 144516381 on Build GRCh38	Loss	LOC101928953 RECQL4 PPP1R16A MFSD3 GPT
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	EXOSC4 LOC101928953 SCRT1 HSF1 SMPD5 PPP1R16A MIR6848 PLEC FOXH1 DGAT1 SHARPIN MROH1 MFSD3 VPS28 MIR6849 CYC1 WDR97 CYHR1 MIR6893 FBXL6 HGH1 BOP1 CPSF1 KIFC2 GPT TMEM249 SPATC1 PARP10 MIR6847 TONSL RECQL4 MIR661 GPAA1 MIR7112 OPLAH MIR1234 LRRC14 MIR6846 ADCK5 MAF1 SCX SLC52A2 GRINA SLC39A4 MIR939 TONSL-AS1 LOC101928902
nsv612940	Chr.8:144436292 - 144613673 on Build GRCh38	Loss	LOC101928953 ARHGAP39 TONSL RECQL4 PPP1R16A FOXH1 LRRC24 MFSD3 LRRC14 C8orf82 CYHR1 TONSL-AS1 KIFC2 GPT
nsv428208	Chr.8:144041826 - 144722291 on Build GRCh38	Gain	EXOSC4 LOC101928953 ARHGAP39 SCRT1 HSF1 SMPD5 PPP1R16A MIR6848 FOXH1 DGAT1 SHARPIN MROH1 MFSD3 VPS28 MIR6849 CYC1 WDR97 C8orf82 CYHR1 MIR6893 FBXL6 HGH1 BOP1 CPSF1 KIFC2 GPT ZNF251 TMEM249 SPATC1 MIR6847 TONSL RECQL4 LRRC24 GPAA1 MIR7112 OPLAH MIR1234 LRRC14 MIR6846 ADCK5 MAF1 SCX SLC52A2 SLC39A4 MIR939 TONSL-AS1 LOC101928902
esv29999	Chr.8:144456732 - 144525122 on Build GRCh38	Loss	LOC101928953 RECQL4 PPP1R16A CYHR1 FOXH1 LRRC24 KIFC2 MFSD3 LRRC14 GPT

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphatase modulator

Gene Ontology Categories:

Process(es)

regulation of catalytic activity

Function(s)

protein binding
protein phosphatase type 1 regulator activity