Hs00995475_cn

• Gene Symbol: YWHAG
• Assay Reference Genome Location: Chr.7:76329895 on build GRCh38
• Cytoband: 7q11.23

Target Gene Details

• Entrez Gene ID: 7532
• Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
• Gene Aliases: 14-3-3GAMMA, PPP1R170
• Location: Chr.7:76326791-76359025 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
YWHAG	NM_012479.3	2	643	NP_036611.2
	AB024334.1	2	595	BAA85184.1
	AF142498.1	2	426	AAD48408.1
	AK024230.1	2	607
	AK293505.1
	AK295029.1	3	522
	BC020963.2	2	617	AAH20963.1
	CR541904.1	2	426	CAG46702.1
	CR541925.1	2	426	CAG46723.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422494	Chr.7:76286900 - 76984449 on Build GRCh38	Duplication	DTX2 SPDYE16 DTX2P1-UPK3BP1-PMS2P11 HSPB1 LOC105375355 LOC100133091 SSC4D FDPSP2 SRRM3 POMZP3 ZP3 YWHAG
nsv428174	Chr.7:76305019 - 77220062 on Build GRCh38	Gain	FGL2 PMS2P9 LOC105375355 LOC100133091 SSC4D ZP3 CCDC146 SPDYE18 DTX2 SPDYE17 SPDYE16 DTX2P1-UPK3BP1-PMS2P11 FDPSP2 POMZP3 YWHAG
nsv528969	Chr.7:75074053 - 76920728 on Build GRCh38	Gain	LOC441259 CCL26 NCF1C STYXL1 MIR4651 CCL24 LOC105375355 LOC100133091 HIP1 SSC4D SPDYE5 PMS2P3 SNORA14A DTX2 TMEM120A GTF2IRD2B FDPSP2 LOC541473 POMZP3 YWHAG NSUN5P1 TRIM73 POR PMS2P10 HSPB1 LOC107986711 SRRM3 MDH2 ZP3 GTF2IP1 PMS2P2 GTF2IP7 SPDYE16 POM121C RHBDD2 STAG3L1
dgv120n16	Chr.7:75440769 - 76641919 on Build GRCh38	Deletion	CCL26 STYXL1 MIR4651 CCL24 LOC105375355 LOC100133091 HIP1 SSC4D SPDYE5 PMS2P3 SNORA14A DTX2 TMEM120A FDPSP2 POMZP3 YWHAG POR HSPB1 LOC107986711 SRRM3 MDH2 ZP3 GTF2IP7 SPDYE16 POM121C RHBDD2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
negative regulation of protein kinase activity
protein targeting
regulation of signal transduction
cellular response to insulin stimulus
regulation of neuron differentiation
regulation of synaptic plasticity
membrane organization
negative regulation of protein serine/threonine kinase activity
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Function(s)

protein kinase C binding
insulin-like growth factor receptor binding
protein binding
protein kinase C inhibitor activity
protein domain specific binding
receptor tyrosine kinase binding
poly(A) RNA binding