Hs01065564_cn

• Gene Symbol: ADRA2B
• Assay Reference Genome Location: Chr.2:96115404 on build GRCh38
• Cytoband: 2q11.2

Target Gene Details

• Entrez Gene ID: 151
• Gene Name: adrenoceptor alpha 2B
• Gene Aliases: ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, FAME2, alpha-2BAR
• Location: Chr.2:96112875-96116245 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADRA2B	NM_000682.6	1	842	NP_000673.2
	BC133021.1	1	842
	BC136537.1	1	842
	CV806541.1	1	287

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv607e201	Chr.2:95855884 - 97561622 on Build GRCh38	Deletion	STARD7-AS1 FAHD2B LOC105373496 KANSL3 FAHD2CP STARD7 CNNM3 ANKRD23 ASTL ANKRD36C ANKRD36B LMAN2L LOC653924 ITPRIPL1 LOC100506076 LOC101927053 MIR3127 FAM178B NEURL3 FER1L5 ARID5A CNNM4 TMEM127 NCAPH LOC105373495 ANKRD36 SNRNP200 LOC100506123 GPAT2 SEMA4C LOC107984110 CIAO1 ADRA2B DUSP2 ANKRD39
nsv2834	Chr.2:96107177 - 96119371 on Build GRCh38	Deletion	ADRA2B
dgv4009n100	Chr.2:96072837 - 96159625 on Build GRCh38	Gain	ADRA2B DUSP2 ASTL
nsv1135873	Chr.2:95981454 - 97579645 on Build GRCh38	Deletion	STARD7-AS1 FAHD2B LOC105373496 KANSL3 FAHD2CP STARD7 CNNM3 ANKRD23 ASTL ANKRD36C ANKRD36B LMAN2L LOC653924 ITPRIPL1 LOC100506076 LOC101927053 MIR3127 FAM178B NEURL3 FER1L5 ARID5A CNNM4 TMEM127 NCAPH LOC105373495 ANKRD36 SNRNP200 LOC100506123 GPAT2 SEMA4C LOC107984110 CIAO1 ADRA2B DUSP2 ANKRD39
esv3425717	Chr.2:95859900 - 97515905 on Build GRCh38	Duplication	STARD7-AS1 FAHD2B LOC105373496 KANSL3 FAHD2CP STARD7 CNNM3 ANKRD23 ASTL ANKRD36C ANKRD36B LMAN2L LOC653924 ITPRIPL1 LOC100506076 LOC101927053 MIR3127 FAM178B NEURL3 FER1L5 ARID5A CNNM4 TMEM127 NCAPH LOC105373495 ANKRD36 SNRNP200 LOC100506123 GPAT2 SEMA4C LOC107984110 CIAO1 ADRA2B DUSP2 ANKRD39

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

regulation of smooth muscle contraction
G-protein coupled receptor signaling pathway
cell-cell signaling
negative regulation of norepinephrine secretion
regulation of vasoconstriction
platelet activation
activation of protein kinase B activity
negative regulation of epinephrine secretion
epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
positive regulation of neuron differentiation
adenylate cyclase-activating adrenergic receptor signaling pathway
activation of MAPK activity by adrenergic receptor signaling pathway

Function(s)

alpha2-adrenergic receptor activity
protein binding
epinephrine binding