Hs01069373_cn

• Gene Symbol: CXCL6
• Assay Reference Genome Location: Chr.4:73838038 on build GRCh38
• Cytoband: 4q13.3

Target Gene Details

• Entrez Gene ID: 6372
• Gene Name: C-X-C motif chemokine ligand 6
• Gene Aliases: CKA-3, GCP-2, GCP2, SCYB6
• Location: Chr.4:73836556-73838760 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CXCL6	NM_002993.3	4	937	NP_002984.1
	BC013744.1	4	772	AAH13744.1
	U81234.1	4	805	AAD00506.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1001725	Chr.4:73488333 - 73995207 on Build GRCh38	Gain	AFM CXCL6 PF4V1 PF4 CXCL1 LOC728040 CXCL8 RASSF6 PPBP
nsv4389	Chr.4:73824830 - 73856555 on Build GRCh38	Insertion	CXCL6 PF4V1

More Information

Additional Information:

For this assay, SNP(s) [rs79466294] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

chemokine

Gene Ontology Categories:

Process(es)

neutrophil mediated immunity
positive regulation of leukocyte chemotaxis
chemotaxis
inflammatory response
immune response
signal transduction
G-protein coupled receptor signaling pathway
cell-cell signaling
response to lipopolysaccharide
regulation of cell proliferation
defense response to bacterium
cell chemotaxis
chemokine-mediated signaling pathway

Function(s)

chemokine activity
heparin binding
CXCR chemokine receptor binding