Hs01089241_cn

• Gene Symbol: FSTL3
• Assay Reference Genome Location: Chr.19:682077 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 10272
• Gene Name: follistatin like 3
• Gene Aliases: FLRG, FSRP
• Location: Chr.19:676389-683392 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FSTL3	NM_005860.2	5	1196	NP_005851.1
	AK291958.1
	AK311566.1	3	821
	AY358917.1	5	1177	AAQ89276.1
	BC005839.2	5	1182	AAH05839.1
	U76702.1	5	1168	AAC64321.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv134n111	Chr.19:607984 - 967584 on Build GRCh38	Deletion	CFD RNU6-9 FGF22 AZU1 MIR3187 PLPPR3 PTBP1 ARID3A POLRMT KISS1R ELANE PALM PRTN3 LOC101928450 MED16 HCN2 MISP FSTL3 R3HDM4 RNF126 MIR4745 PRSS57
nsv428360	Chr.19:232069 - 702131 on Build GRCh38	Gain	CDC34 FGF22 C2CD4C MADCAM1 POLRMT ODF3L2 SHC2 HCN2 BSG GZMM PLPP2 THEG MIER2 FSTL3 RNF126 LOC101929060 TPGS1 PRSS57
nsv577978	Chr.19:294526 - 782854 on Build GRCh38	Gain	CDC34 FGF22 C2CD4C MADCAM1 POLRMT ODF3L2 PALM LOC101928450 SHC2 HCN2 BSG GZMM MISP THEG MIER2 FSTL3 RNF126 LOC101929060 TPGS1 PRSS57
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	RNU6-9 CNN2 C2CD4C AZU1 MIR3187 PTBP1 MADCAM1 ARID3A POLRMT WDR18 ODF3L2 PALM LOC101928450 MISP GPX4 R3HDM4 TMEM259 POLR2E RNU6-2 RNF126 MIR4745 TPGS1 PRSS57 CFD CDC34 FGF22 PLPPR3 ARHGAP45 KISS1R ELANE PRTN3 SHC2 MED16 HCN2 BSG GZMM THEG FSTL3 ABCA7 LOC105372235 GRIN3B
nsv470101	Chr.19:401714 - 1008505 on Build GRCh38	Loss	RNU6-9 C2CD4C AZU1 MIR3187 PTBP1 MADCAM1 ARID3A POLRMT WDR18 ODF3L2 PALM LOC101928450 MISP R3HDM4 RNF126 MIR4745 TPGS1 PRSS57 CFD CDC34 FGF22 PLPPR3 KISS1R ELANE PRTN3 SHC2 MED16 HCN2 BSG GZMM FSTL3 LOC105372235 GRIN3B

More Information

Additional Information:

For this assay, SNP(s) [rs72976224] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

extracellular matrix glycoprotein

Gene Ontology Categories:

Process(es)

ossification
kidney development
hematopoietic progenitor cell differentiation
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
spermatogenesis
male gonad development
positive regulation of cell-cell adhesion
lung development
adrenal gland development
negative regulation of BMP signaling pathway
negative regulation of activin receptor signaling pathway
negative regulation of osteoclast differentiation
positive regulation of transcription from RNA polymerase II promoter
cellular response to metal ion
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

Function(s)

fibronectin binding
protein binding
activin binding