Hs01139766_cn

• Gene Symbol: CDK9
• Assay Reference Genome Location: Chr.9:127786751 on build GRCh38
• Cytoband: 9q34.11

Target Gene Details

• Entrez Gene ID: 1025
• Gene Name: cyclin dependent kinase 9
• Gene Aliases: C-2k, CDC2L4, CTK1, PITALRE, TAK
• Location: Chr.9:127786026-127790782 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDK9	NM_001261.3			NP_001252.1
	XM_017014184.1			XP_016869673.1
	AB451289.1
	AB451421.1
	AK313828.1
	BC001968.1			AAH01968.1
	BT019903.1			AAV38706.1
	DB120461.1
	L25676.1			AAA35668.1
	X80230.1			CAA56516.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv12879n54	Chr.9:127731234 - 127824409 on Build GRCh38	Loss	ENG SH2D3C MIR3960 TOR2A MIR2861 TTC16 LOC102723566 CDK9 FPGS
nsv825094	Chr.9:127742027 - 127802620 on Build GRCh38	Gain	SH2D3C MIR3960 MIR2861 CDK9
nsv471323	Chr.9:127727464 - 127845239 on Build GRCh38	Loss	ENG SH2D3C MIR3960 TOR2A MIR2861 TTC16 LOC102723566 CDK9 FPGS
nsv466573	Chr.9:127735841 - 127787855 on Build GRCh38	Loss	SH2D3C MIR3960 MIR2861 CDK9
nsv615373	Chr.9:127764326 - 127817625 on Build GRCh38	Loss	ENG SH2D3C MIR3960 MIR2861 LOC102723566 CDK9 FPGS
nsv615374	Chr.9:127770709 - 127866860 on Build GRCh38	Loss	AK1 ENG SH2D3C MIR3960 MIR2861 LOC102723566 CDK9 FPGS

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

DNA repair
regulation of DNA repair
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
protein phosphorylation
regulation of mitotic cell cycle
cell proliferation
positive regulation of cardiac muscle hypertrophy
regulation of histone modification
replication fork processing
positive regulation of histone phosphorylation
response to drug
snRNA transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter
positive regulation of viral transcription
regulation of muscle cell differentiation
negative regulation of cell cycle arrest
cellular response to cytokine stimulus
negative regulation of mRNA polyadenylation
positive regulation of mRNA 3'-UTR binding
positive regulation of histone H2B ubiquitination

Function(s)

RNA polymerase II core promoter sequence-specific DNA binding
transcription coactivator binding
DNA binding
chromatin binding
protein kinase activity
protein serine/threonine kinase activity
cyclin-dependent protein serine/threonine kinase activity
protein binding
ATP binding
RNA polymerase II carboxy-terminal domain kinase activity
kinase activity
7SK snRNA binding