Hs01162533_cn

• Gene Symbol: ADCYAP1
• Assay Reference Genome Location: Chr.18:909533 on build GRCh38
• Cytoband: 18p11.32

Target Gene Details

• Entrez Gene ID: 116
• Gene Name: adenylate cyclase activating polypeptide 1
• Gene Aliases: PACAP
• Location: Chr.18:904342-912172 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADCYAP1	NM_001099733.1	5	548	NP_001093203.1
	NM_001117.4	4	620	NP_001108.2
	XM_005258081.3	6	947	XP_005258138.1
	AK294233.1	6	876
	AK313050.1	5	548
	BC093837.1	4	500	AAH93837.1
	BC101803.1	4	500	AAI01804.1
	DC320719.1
	DN991692.1	4	527
	S83513.1	4	430	AAB21470.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv517252	Chr.18:902327 - 910634 on Build GRCh38	Loss	ADCYAP1
dgv5810n54	Chr.18:351004 - 2238246 on Build GRCh38	Gain	CETN1 ADCYAP1 LOC388456 ENOSF1 LINC00470 TYMS TYMSOS LOC105376854 CLUL1 YES1 COLEC12
nsv528169	Chr.18:551688 - 2240220 on Build GRCh38	Loss	CETN1 ADCYAP1 LOC388456 ENOSF1 LINC00470 TYMS TYMSOS CLUL1 YES1
dgv5811n54	Chr.18:841320 - 1798153 on Build GRCh38	Gain	ADCYAP1 LOC388456 LINC00470
nsv482935	Chr.18:10001 - 2900002 on Build GRCh38	Loss	EMILIN2 CETN1 ADCYAP1 LOC388456 ENOSF1 SMCHD1 NDC80 TYMS TYMSOS LOC105376854 CLUL1 COLEC12 MIR8078 METTL4 LINC00470 CBX3P2 THOC1 USP14 ROCK1P1 LOC101926997 YES1
nsv576228	Chr.18:69836 - 1506323 on Build GRCh38	Loss	CETN1 ADCYAP1 LOC388456 ENOSF1 TYMS TYMSOS LOC105376854 CLUL1 COLEC12 MIR8078 LINC00470 THOC1 USP14 ROCK1P1 YES1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

neuropeptide

Gene Ontology Categories:

Process(es)

ovarian follicle development
behavioral fear response
histamine secretion
negative regulation of acute inflammatory response to antigenic stimulus
negative regulation of acute inflammatory response to non-antigenic stimulus
activation of adenylate cyclase activity
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
cell-cell signaling
female pregnancy
regulation of G-protein coupled receptor protein signaling pathway
positive regulation of cell proliferation
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
negative regulation of muscle cell apoptotic process
positive regulation of neuron projection development
sensory perception of pain
cAMP-mediated signaling
pituitary gland development
neuron projection development
positive regulation of interleukin-6 production
regulation of protein localization
negative regulation of GTPase activity
response to starvation
negative regulation of potassium ion transport
positive regulation of GTPase activity
response to ethanol
negative regulation of cell cycle
positive regulation of protein kinase activity
positive regulation of vasodilation
positive regulation of transcription from RNA polymerase II promoter
ATP metabolic process
positive regulation of synaptic transmission, glutamatergic
regulation of postsynaptic membrane potential
positive regulation of growth hormone secretion
negative regulation of glial cell proliferation
positive regulation of ERK1 and ERK2 cascade
regulation of oligodendrocyte progenitor proliferation
cellular response to glucocorticoid stimulus
positive regulation of chemokine (C-C motif) ligand 5 production
positive regulation of somatostatin secretion

Function(s)

receptor signaling protein activity
receptor binding
neuropeptide hormone activity
protein binding
pituitary adenylate cyclase activating polypeptide activity
pituitary adenylate cyclase-activating polypeptide receptor binding
peptide hormone receptor binding