Hs01169587_cn

• Gene Symbol: PPP1R15B
• Assay Reference Genome Location: Chr.1:204410004 on build GRCh38
• Cytoband: 1q32.1

Target Gene Details

• Entrez Gene ID: 84919
• Gene Name: protein phosphatase 1 regulatory subunit 15B
• Gene Aliases: CREP, MSSGM2
• Location: Chr.1:204398684-204411880 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPP1R15B	NM_032833.4	1	1814	NP_116222.4
	XM_005245551.4	1	1877	XP_005245608.2
	AK027650.1	1	1814	BAB55266.1
	AK222877.1	1	1815	BAD96597.1
	AK303535.1	2	1368
	AK316092.1	2	1426
	AL833746.1	1	491	CAH56240.1
	BC065280.1	1	1788	AAH65280.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv952641	Chr.1:204396873 - 204410972 on Build GRCh38	Duplication	PPP1R15B

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
ER overload response
response to hydrogen peroxide
peptidyl-serine dephosphorylation
negative regulation of PERK-mediated unfolded protein response
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation

Function(s)

protein serine/threonine phosphatase activity
protein binding