Hs01185375_cn

• Gene Symbol: PTPN18
• Assay Reference Genome Location: Chr.2:130359637 on build GRCh38
• Cytoband: 2q21.1

Target Gene Details

• Entrez Gene ID: 26469
• Gene Name: protein tyrosine phosphatase, non-receptor type 18
• Gene Aliases: BDP1, PTP-HSCF
• Location: Chr.2:130356007-130375409 on Build GRCh38
• Assay Gene Location: Overlaps Intron 4 - Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTPN18	NM_001142370.1			NP_001135842.1
	NM_014369.3			NP_055184.2
	XM_006712416.3			XP_006712479.1
	XM_006712417.1			XP_006712480.1
	XM_017003798.1			XP_016859287.1
	AK303804.1
	BC024280.1			AAH24280.1
	BC041562.1			AAH41562.1
	BC052800.1			AAH52800.1
	BI261717.1
	DN995571.1
	X79568.1			CAA56105.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv998333	Chr.2:130059754 - 130454126 on Build GRCh38	Gain+Loss	FAR2P2 POTEF SMPD4 IMP4 CYP4F62P NOC2LP1 CCDC115 MZT2B MED15P9 PTPN18 TUBA3E CCDC74B
nsv459341	Chr.2:130281566 - 130390535 on Build GRCh38	Loss	IMP4 CCDC115 PTPN18
esv2760631	Chr.2:130005319 - 130400286 on Build GRCh38	Gain+Loss	POTEF SMPD4 FAR2P1 IMP4 NOC2LP1 CCDC115 MZT2B MED15P9 PTPN18 TUBA3E CCDC74B
dgv7079n54	Chr.2:130181715 - 130391244 on Build GRCh38	Loss	SMPD4 IMP4 NOC2LP1 CCDC115 MZT2B PTPN18 TUBA3E
nsv583113	Chr.2:130132813 - 130369588 on Build GRCh38	Gain	SMPD4 IMP4 NOC2LP1 CCDC115 MZT2B MED15P9 PTPN18 TUBA3E CCDC74B
esv3584065	Chr.2:130046530 - 130400286 on Build GRCh38	Loss	POTEF SMPD4 FAR2P1 IMP4 NOC2LP1 CCDC115 MZT2B MED15P9 PTPN18 TUBA3E CCDC74B
nsv520559	Chr.2:130133334 - 130390535 on Build GRCh38	Gain+Loss	SMPD4 IMP4 NOC2LP1 CCDC115 MZT2B MED15P9 PTPN18 TUBA3E CCDC74B
nsv1005664	Chr.2:130159287 - 130649604 on Build GRCh38	Loss	FAR2P2 IMP4 CYP4F62P NOC2LP1 CFC1B PTPN18 LOC646743 TUBA3E SMPD4 POTEI POTEJ CCDC115 LOC107985778 MZT2B TISP43 CFC1
esv2763387	Chr.2:130026123 - 130400286 on Build GRCh38	Loss	POTEF SMPD4 FAR2P1 IMP4 NOC2LP1 CCDC115 MZT2B MED15P9 PTPN18 TUBA3E CCDC74B
dgv475n27	Chr.2:130185940 - 130390535 on Build GRCh38	Gain	IMP4 NOC2LP1 CCDC115 MZT2B PTPN18 TUBA3E
dgv7083n54	Chr.2:130236250 - 130440530 on Build GRCh38	Loss	FAR2P2 IMP4 CYP4F62P CCDC115 PTPN18
nsv583046	Chr.2:128746961 - 130390535 on Build GRCh38	Loss	RAB6C-AS1 FAR2P1 IMP4 NOC2LP1 LOC389033 MED15P9 LOC151121 PTPN18 TUBA3E CCDC74B POTEF SMPD4 LOC101927881 LOC101927924 CCDC115 MZT2B RAB6C
esv3592450	Chr.2:130282861 - 130401532 on Build GRCh38	Loss	IMP4 CCDC115 PTPN18
nsv583132	Chr.2:130255764 - 130390535 on Build GRCh38	Gain	IMP4 CCDC115 PTPN18
nsv1001073	Chr.2:130290533 - 130400286 on Build GRCh38	Gain	IMP4 CCDC115 PTPN18
esv2751826	Chr.2:129606158 - 130385563 on Build GRCh38	Gain	RAB6C-AS1 FAR2P1 IMP4 NOC2LP1 LOC389033 MED15P9 PTPN18 TUBA3E CCDC74B POTEF SMPD4 LOC101927924 CCDC115 MZT2B RAB6C
esv2759092	Chr.2:129589265 - 132440430 on Build GRCh38	Gain+Loss	CYP4F30P POTEE FAR2P1 LOC100507460 IMP4 CFC1B CCDC74A ANKRD30BL POTEF PLEKHB2 LOC101927924 CFC1 TUBA3D GPR148 LOC150776 CYP4F62P NOC2LP1 GPR39 LOC389033 CCDC74B C2orf27B NOC2LP2 POTEJ LOC107985778 TISP43 RAB6C-AS1 FAR2P2 AMER3 MED15P9 FAM168B WTH3DI CCDC115 MZT2B LINC01087 RAB6C MIR663B POTEKP MZT2A LINC01120 ZNF806 PTPN18 LOC646743 TUBA3E FAM201B SMPD4 ARHGEF4 C2orf27A POTEI MIR4784 LOC440910
dgv4073n100	Chr.2:130091652 - 130400286 on Build GRCh38	Gain	POTEF SMPD4 IMP4 NOC2LP1 CCDC115 MZT2B MED15P9 PTPN18 TUBA3E CCDC74B
esv3893326	Chr.2:130080351 - 130492798 on Build GRCh38	Gain	FAR2P2 IMP4 CYP4F62P NOC2LP1 MED15P9 PTPN18 TUBA3E CCDC74B POTEF SMPD4 POTEI CCDC115 MZT2B
nsv428403	Chr.2:129818076 - 130882067 on Build GRCh38	Loss	CYP4F30P RAB6C-AS1 FAR2P2 FAR2P1 IMP4 AMER3 MED15P9 CFC1B POTEF LOC101927924 CCDC115 MZT2B RAB6C CFC1 GPR148 CYP4F62P NOC2LP1 LOC389033 PTPN18 LOC646743 TUBA3E CCDC74B SMPD4 ARHGEF4 POTEI POTEJ LOC107985778 TISP43

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

protein dephosphorylation
peptidyl-tyrosine dephosphorylation

Function(s)

non-membrane spanning protein tyrosine phosphatase activity
protein binding