Hs01194385_cn

• Gene Symbol: TRMT2A
• Assay Reference Genome Location: Chr.22:20113779 on build GRCh38
• Cytoband: 22q11.21

Target Gene Details

• Entrez Gene ID: 27037
• Gene Name: tRNA methyltransferase 2 homolog A
• Gene Aliases: HTF9C
• Location: Chr.22:20111866-20117305 on Build GRCh38
• Assay Gene Location: Overlaps Intron 7 - Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRMT2A	NM_001257994.1			NP_001244923.1
	NM_022727.5			NP_073564.3
	NM_182984.4			NP_892029.2
	XM_011530139.2			XP_011528441.1
	XM_011530141.1			XP_011528443.1
	XM_011530142.2			XP_011528444.1
	XM_017028770.1			XP_016884259.1
	AK025106.1			BAB15067.1
	AK057029.1			BAB71349.1
	BC013352.2			AAH13352.2
	BC017184.2			AAH17184.2
	BC108251.1			AAI08252.1
	CR456354.1			CAG30240.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv726n67	Chr.22:20070444 - 20324465 on Build GRCh38	Gain	RTN4R LOC284865 MIR1286 RANBP1 DGCR8 ZDHHC8 MIR3618 DGCR6L MIR1306 MIR6816 TRMT2A LINC00896 LOC440792 CCDC188
esv3893434	Chr.22:19470889 - 20343372 on Build GRCh38	Gain	TXNRD2 GP1BB TBX1 MIR1286 MIR4761 TANGO2 RANBP1 CLDN5 MIR3618 MIR1306 MIR6816 MIR185 LOC101927859 RTN4R CDC45 LOC284865 C22orf29 DGCR8 ZDHHC8 COMT GNB1L DGCR6L SEPT5-GP1BB TRMT2A LINC00896 LINC00895 ARVCF UFD1L LOC440792 SEPT5 CCDC188
esv3647284	Chr.22:19985583 - 20137122 on Build GRCh38	Gain	RANBP1 DGCR8 MIR185 ZDHHC8 MIR3618 MIR1306 MIR6816 TRMT2A ARVCF TANGO2
nsv828938	Chr.22:19691069 - 20324465 on Build GRCh38	Gain	TXNRD2 GP1BB TBX1 MIR1286 MIR4761 TANGO2 RANBP1 MIR3618 MIR1306 MIR6816 MIR185 RTN4R LOC284865 C22orf29 DGCR8 ZDHHC8 COMT GNB1L DGCR6L SEPT5-GP1BB TRMT2A LINC00896 ARVCF LOC440792 SEPT5 CCDC188
nsv828939	Chr.22:19696032 - 20324465 on Build GRCh38	Loss	TXNRD2 GP1BB TBX1 MIR1286 MIR4761 TANGO2 RANBP1 MIR3618 MIR1306 MIR6816 MIR185 RTN4R LOC284865 C22orf29 DGCR8 ZDHHC8 COMT GNB1L DGCR6L SEPT5-GP1BB TRMT2A LINC00896 ARVCF LOC440792 SEPT5 CCDC188
esv2758825	Chr.22:20038970 - 20321924 on Build GRCh38	Loss	RTN4R LOC284865 MIR1286 TANGO2 RANBP1 DGCR8 ZDHHC8 MIR3618 DGCR6L MIR1306 MIR6816 TRMT2A LINC00896 LOC440792 CCDC188
dgv4480n100	Chr.22:20069620 - 20262667 on Build GRCh38	Gain	RANBP1 DGCR8 ZDHHC8 RTN4R MIR3618 LOC284865 MIR1306 MIR6816 TRMT2A LINC00896 MIR1286 CCDC188
nsv471183	Chr.22:20018517 - 20319470 on Build GRCh38	Loss	MIR185 RTN4R LOC284865 MIR1286 TANGO2 RANBP1 DGCR8 ZDHHC8 MIR3618 DGCR6L MIR1306 MIR6816 TRMT2A LINC00896 LOC440792 CCDC188
dgv7983n54	Chr.22:19762002 - 20321870 on Build GRCh38	Gain	MIR185 TXNRD2 RTN4R TBX1 LOC284865 MIR1286 MIR4761 C22orf29 TANGO2 RANBP1 DGCR8 ZDHHC8 MIR3618 COMT GNB1L DGCR6L MIR1306 MIR6816 TRMT2A LINC00896 ARVCF LOC440792 CCDC188
nsv834133	Chr.22:20029363 - 20176708 on Build GRCh38	Loss	RANBP1 DGCR8 MIR185 ZDHHC8 MIR3618 MIR1306 MIR6816 TRMT2A CCDC188 TANGO2
nsv953027	Chr.22:20085378 - 20303977 on Build GRCh38	Deletion	RTN4R LOC284865 MIR1286 RANBP1 DGCR8 ZDHHC8 MIR3618 MIR1306 MIR6816 TRMT2A LINC00896 LOC440792 CCDC188

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA methyltransferase

Gene Ontology Categories:

Process(es)

RNA methylation
RNA processing

Function(s)

nucleotide binding
RNA methyltransferase activity
poly(A) RNA binding