Hs01194667_cn

• Gene Symbol: PXDN
• Assay Reference Genome Location: Chr.2:1632078 on build GRCh38
• Cytoband: 2p25.3

Target Gene Details

• Entrez Gene ID: 7837
• Gene Name: peroxidasin
• Gene Aliases: COPOA, D2S448, D2S448E, MG50, PRG2, PXN, VPO
• Location: Chr.2:1631887-1744852 on Build GRCh38
• Assay Gene Location: Within Exon 25

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PXDN	NM_012293.2	23	6658	NP_036425.1
	XM_005264707.3	22	6574	XP_005264764.1
	XM_011510396.1	23	6415	XP_011508698.1
	XM_011510397.2	22	6503	XP_011508699.1
	AF200348.1	23	6617	AAF06354.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1005443	Chr.2:1080998 - 1747280 on Build GRCh38	Gain	SNTG2 LOC107985837 LOC102723730 PXDN TPO
nsv521199	Chr.2:1622620 - 1648888 on Build GRCh38	Loss	PXDN
esv3891470	Chr.2:1005374 - 1856757 on Build GRCh38	Gain	SNTG2 MYT1L LOC107985837 LOC102723730 PXDN TPO
nsv1007175	Chr.2:1621349 - 1672921 on Build GRCh38	Gain	PXDN
nsv1007958	Chr.2:1615448 - 1853325 on Build GRCh38	Gain	MYT1L PXDN

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

peroxidase

Gene Ontology Categories:

Process(es)

negative regulation of cytokine-mediated signaling pathway
immune response
response to oxidative stress
extracellular matrix organization
hydrogen peroxide catabolic process
oxidation-reduction process
cellular oxidant detoxification

Function(s)

peroxidase activity
interleukin-1 receptor antagonist activity
extracellular matrix structural constituent
heme binding
metal ion binding