Hs01202740_cn

• Gene Symbol: NDOR1
• Assay Reference Genome Location: Chr.9:137214224 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 27158
• Gene Name: NADPH dependent diflavin oxidoreductase 1
• Gene Aliases: NR1, bA350O14.9
• Location: Chr.9:137205667-137219361 on Build GRCh38
• Assay Gene Location: Overlaps Intron 4 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NDOR1	NM_001144026.2			NP_001137498.1
	NM_001144027.2			NP_001137499.1
	NM_001144028.2			NP_001137500.1
	NM_014434.3			NP_055249.1
	XM_011518545.1			XP_011516847.1
	XM_011518547.1			XP_011516849.1
	XM_011518548.2			XP_011516850.1
	XM_017014626.1			XP_016870115.1
	XM_017014627.1			XP_016870116.1
	AF199509.1			AAF25205.1
	AK026089.1
	AK074403.1
	AK225995.1
	AK290026.1
	AY077845.1			AAL77754.1
	BC015735.1			AAH15735.1
	BC093782.1			AAH93782.1
	BC111943.1			AAI11944.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13010n54	Chr.9:137191539 - 137233413 on Build GRCh38	Loss	RNF208 TPRN TMEM203 RNF224 NDOR1 CYSRT1 SLC34A3
nsv616012	Chr.9:137197680 - 137223834 on Build GRCh38	Loss	RNF208 TPRN TMEM203 NDOR1
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	TMEM210 TMEM203 RNF224 LRRC26 NDOR1 SLC34A3 MIR3621 RNF208 UAP1L1 LOC101930307 TPRN MAN1B1 MAN1B1-AS1 ANAPC2 SSNA1 DPP7 CYSRT1 GRIN1
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	C9orf173-AS1 TOR4A FAM166A NRARP TMEM203 RNF224 NDOR1 SLC34A3 RNF208 STPG3 NELFB TPRN TUBB4B ANAPC2 SSNA1 CYSRT1 EXD3
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	C8G C9orf139 C9orf173-AS1 FAM166A RNF224 EDF1 CYSRT1 MIR4479 NSMF ENTPD2 ABCA2 MIR3621 UAP1L1 NELFB LCNL1 TRAF2 CLIC3 TUBB4B PTGDS DPP7 NPDC1 PRR31 GRIN1 TMEM210 FUT7 TOR4A LRRC26 NDOR1 PNPLA7 MIR4292 RNF208 STPG3 C9orf172 PHPT1 RABL6 SSNA1 FBXW5 LCN12 MIR7114 CCDC183-AS1 NOXA1 NRARP TMEM203 SAPCD2 SLC34A3 CCDC183 C9orf142 LOC101930307 TPRN MAN1B1 MAN1B1-AS1 ANAPC2 EXD3 MAMDC4 ENTPD8
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	TMEM210 C9orf173-AS1 TOR4A FAM166A NRARP TMEM203 RNF224 LRRC26 NDOR1 SLC34A3 MIR3621 RNF208 STPG3 NELFB TPRN TUBB4B ANAPC2 SSNA1 CYSRT1 EXD3 GRIN1
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	NOXA1 TMEM210 C9orf173-AS1 TOR4A FAM166A NRARP TMEM203 RNF224 LRRC26 NDOR1 SLC34A3 MIR3621 RNF208 STPG3 NELFB TPRN TUBB4B ANAPC2 SSNA1 CYSRT1 EXD3 ENTPD8 GRIN1
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	C8G C9orf139 C9orf173-AS1 FAM166A HSPC324 RNF224 FAM69B TMEM141 EDF1 CYSRT1 SNHG7 LCN15 MIR4479 LCN6 LOC100128593 ENTPD2 ABCA2 MIR3621 MIR126 UAP1L1 NELFB LCNL1 TRAF2 LINC01451 CLIC3 TUBB4B PTGDS DPP7 NPDC1 PRR31 GRIN1 LCN10 TMEM210 FUT7 TOR4A LCN8 AGPAT2 LRRC26 NDOR1 MIR4292 RNF208 STPG3 C9orf172 PHPT1 RABL6 MIR6722 SSNA1 FBXW5 LCN12 CCDC183-AS1 NRARP EGFL7 TMEM203 SAPCD2 SLC34A3 CCDC183 SNORA17B SNORA17A C9orf142 LOC101930307 TPRN MAN1B1 MAN1B1-AS1 ANAPC2 EXD3 MAMDC4

More Information

Additional Information:

For this assay, SNP(s) [rs77510769] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

cell death
iron-sulfur cluster assembly
cellular response to menadione
oxidation-reduction process

Function(s)

NADPH-hemoprotein reductase activity
protein binding
FMN binding
oxidoreductase activity
flavin adenine dinucleotide binding
NADP binding