Hs01202740_cn

• Gene Symbol: NDOR1
• Assay Reference Genome Location: Chr.9:137214224 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 27158
• Gene Name: NADPH dependent diflavin oxidoreductase 1
• Gene Aliases: NR1, bA350O14.9
• Location: Chr.9:137205667-137219361 on Build GRCh38
• Assay Gene Location: Overlaps Intron 4 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NDOR1	NM_001144026.2			NP_001137498.1
	NM_001144027.2			NP_001137499.1
	NM_001144028.2			NP_001137500.1
	NM_014434.3			NP_055249.1
	XM_011518545.1			XP_011516847.1
	XM_011518547.1			XP_011516849.1
	XM_011518548.2			XP_011516850.1
	XM_017014626.1			XP_016870115.1
	XM_017014627.1			XP_016870116.1
	AF199509.1			AAF25205.1
	AK026089.1
	AK074403.1
	AK225995.1
	AK290026.1
	AY077845.1			AAL77754.1
	BC015735.1			AAH15735.1
	BC093782.1			AAH93782.1
	BC111943.1			AAI11944.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13010n54	Chr.9:137191539 - 137233413 on Build GRCh38	Loss	NDOR1 RNF208 TMEM203 SLC34A3 CYSRT1 RNF224 TPRN
nsv616012	Chr.9:137197680 - 137223834 on Build GRCh38	Loss	NDOR1 RNF208 TMEM203 TPRN
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	SLC34A3 MAN1B1-AS1 GRIN1 MIR3621 UAP1L1 LRRC26 SSNA1 TMEM210 MAN1B1 NDOR1 RNF208 TMEM203 CYSRT1 DPP7 RNF224 TPRN LOC101930307 ANAPC2
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	EXD3 SLC34A3 NRARP C9orf173-AS1 SSNA1 FAM166A NDOR1 STPG3 RNF208 NELFB TMEM203 CYSRT1 RNF224 TPRN TUBB4B ANAPC2 TOR4A
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	SLC34A3 MAN1B1-AS1 NRARP LRRC26 ABCA2 SSNA1 NDOR1 TMEM203 CYSRT1 CCDC183-AS1 LOC101930307 FBXW5 TOR4A MIR3621 C8G C9orf142 EDF1 LCN12 CLIC3 ENTPD8 TUBB4B ANAPC2 MIR4479 PTGDS TRAF2 EXD3 MAMDC4 UAP1L1 C9orf173-AS1 NOXA1 PRR31 MAN1B1 MIR4292 NELFB DPP7 NSMF TPRN PHPT1 C9orf139 SAPCD2 MIR7114 GRIN1 NPDC1 ENTPD2 C9orf172 FAM166A CCDC183 TMEM210 PNPLA7 STPG3 RNF208 RABL6 FUT7 LCNL1 RNF224
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	EXD3 SLC34A3 GRIN1 NRARP MIR3621 C9orf173-AS1 LRRC26 SSNA1 FAM166A TMEM210 NDOR1 STPG3 RNF208 NELFB TMEM203 CYSRT1 RNF224 TPRN TUBB4B ANAPC2 TOR4A
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	EXD3 SLC34A3 GRIN1 NRARP MIR3621 C9orf173-AS1 NOXA1 LRRC26 SSNA1 FAM166A TMEM210 NDOR1 STPG3 RNF208 NELFB TMEM203 CYSRT1 ENTPD8 RNF224 TPRN TUBB4B ANAPC2 TOR4A
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	LCN15 SLC34A3 MAN1B1-AS1 NRARP LRRC26 ABCA2 SSNA1 NDOR1 TMEM203 CYSRT1 CCDC183-AS1 LOC101930307 FBXW5 TOR4A MIR3621 C8G C9orf142 EDF1 LCN12 CLIC3 MIR6722 TMEM141 TUBB4B ANAPC2 MIR4479 PTGDS TRAF2 AGPAT2 EXD3 LCN8 MAMDC4 UAP1L1 C9orf173-AS1 PRR31 MAN1B1 MIR4292 SNORA17B SNORA17A NELFB DPP7 TPRN FAM69B PHPT1 LCN10 MIR126 C9orf139 SAPCD2 HSPC324 GRIN1 EGFL7 NPDC1 ENTPD2 LOC100128593 C9orf172 FAM166A CCDC183 TMEM210 LCN6 LINC01451 STPG3 RNF208 RABL6 FUT7 LCNL1 RNF224 SNHG7

More Information

Additional Information:

For this assay, SNP(s) [rs77510769] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

cell death
iron-sulfur cluster assembly
cellular response to menadione
oxidation-reduction process

Function(s)

NADPH-hemoprotein reductase activity
protein binding
FMN binding
oxidoreductase activity
flavin adenine dinucleotide binding
NADP binding