Hs01209398_cn

• Gene Symbol: CYB561A3
• Assay Reference Genome Location: Chr.11:61349257 on build GRCh38
• Cytoband: 11q12.2

Target Gene Details

• Entrez Gene ID: 220002
• Gene Name: cytochrome b561 family member A3
• Gene Aliases: CYBASC3, LCYTB
• Location: Chr.11:61348748-61362299 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYB561A3	NM_001161452.1	5	2047	NP_001154924.1
	NM_001161454.1	8	2702	NP_001154926.1
	NM_001300763.1	7	1754	NP_001287692.1
	NM_153611.4	7	2533	NP_705839.3
	XM_011544821.1	8	1939	XP_011543123.1
	XM_011544823.1	6	1674	XP_011543125.1
	XM_017017345.1	9	3856	XP_016872834.1
	XM_017017346.1	8	3687	XP_016872835.1
	XM_017017347.1	6	1296	XP_016872836.1
	AI813810.1
	AK024953.1	4	1497
	AK025870.1	3	1380
	AK056751.1	7	2524
	AK075559.1	7	2134	BAC11698.1
	AL833374.1	3	1364
	BC004391.1	7	2507	AAH04391.1
	BC014045.2	7	2343	AAH14045.2
	BC047710.1	7	2052	AAH47710.1
	BM692535.1
	BP396674.1
	CF541093.1	1	468

Target Gene Details

• Entrez Gene ID: 26007
• Gene Name: triokinase and FMN cyclase
• Gene Aliases: DAK, NET45
• Location: Chr.11:61333182-61353426 on Build GRCh38
• Assay Gene Location: Within Intron 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TKFC	XM_017017518.1			XP_016873007.1
	XM_017017522.1			XP_016873011.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428259	Chr.11:61049513 - 61356164 on Build GRCh38	Gain+Loss	PGA4 CYB561A3 VPS37C PGA3 TKFC PGA5 LOC105369325 VWCE CD5 DDB1
nsv832177	Chr.11:61185118 - 61356164 on Build GRCh38	Loss	PGA4 CYB561A3 PGA3 TKFC PGA5 VWCE DDB1

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

reductase, cyclase

Gene Ontology Categories:

Process(es)

oxidation-reduction process
glycerol metabolic process
negative regulation of MDA-5 signaling pathway
cellular carbohydrate metabolic process
innate immune response
regulation of innate immune response
carbohydrate phosphorylation
fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

Function(s)

protein binding
oxidoreductase activity
metal ion binding
glycerone kinase activity
ATP binding
FAD-AMP lyase (cyclizing) activity
triokinase activity