Hs01231353_cn

• Gene Symbol: GGT5
• Assay Reference Genome Location: Chr.22:24231479 on build GRCh38
• Cytoband: 22q11.23

Target Gene Details

• Entrez Gene ID: 2687
• Gene Name: gamma-glutamyltransferase 5
• Gene Aliases: GGL, GGT 5, GGT-REL, GGTLA1
• Location: Chr.22:24219654-24245142 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GGT5	NM_001099781.2	6	1223	NP_001093251.1
	NM_001099782.2	5	1127	NP_001093252.1
	NM_001302464.1	5	1127	NP_001289393.1
	NM_001302465.1	4	992	NP_001289394.1
	NM_004121.3	6	1223	NP_004112.2
	XM_005261557.2	6	1159	XP_005261614.1
	XM_005261558.2	6	1159	XP_005261615.1
	XM_011530133.1	6	1159	XP_011528435.1
	XM_011530134.1	6	1159	XP_011528436.1
	XM_011530135.1	5	1063	XP_011528437.1
	XM_011530136.1	6	1159	XP_011528438.1
	XM_011530137.2	6	1159	XP_011528439.1
	XM_017028768.1	5	1063	XP_016884257.1
	XM_017028769.1	5	1063	XP_016884258.1
	AK225661.1	5	1063
	AK226019.1	5	1063
	AK292006.1	6	1005
	AK293683.1	4	932
	AK297869.1	7	998
	AK304522.1	2	578
	AK312401.1	6	1159
	AL117414.1	5	1068	CAB55910.1
	BC011362.1	6	1212	AAH11362.1
	BC073999.1	6	1140	AAH73999.1
	BT009808.1	6	806	AAP88810.1
	CT841518.1	6	964	CAJ86448.1
	M64099.1	6	1147	AAA58503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv8039n54	Chr.22:23323169 - 24601506 on Build GRCh38	Gain	SLC2A11 LOC100652871 LOC107985555 GSTTP1 ADORA2A DDTL GSTT2 SNRPD3 CABIN1 ZNF70 MIF-AS1 LOC107985559 LOC101929374 VPREB3 CES5AP1 GGT1 MIF RGL4 MMP11 POM121L9P DDT UPB1 SMARCB1 DRICH1 CHCHD10 GGT5 SPECC1L-ADORA2A PCAT14 LRRC75B ZDHHC8P1 ADORA2A-AS1 GSTT2B SPECC1L GUCD1 LOC388882 IGLL1 GUSBP11 DERL3 C22orf15 SUSD2
nsv483072	Chr.22:24074769 - 24269273 on Build GRCh38	Loss	CABIN1 GGT5 SUSD2 POM121L9P
nsv1055830	Chr.22:24005071 - 24643213 on Build GRCh38	Gain	UPB1 GGT5 SPECC1L-ADORA2A GSTTP1 LRRC75B ADORA2A ADORA2A-AS1 SNRPD3 SPECC1L GUCD1 CABIN1 BCRP3 GGT1 SUSD2 POM121L9P
nsv834157	Chr.22:24057654 - 24242235 on Build GRCh38	Gain	CABIN1 GGT5 SUSD2
nsv528842	Chr.22:24139262 - 24247641 on Build GRCh38	Loss	CABIN1 GGT5 SUSD2
nsv834158	Chr.22:24126288 - 24293870 on Build GRCh38	Gain	CABIN1 GGT5 SPECC1L-ADORA2A SUSD2 POM121L9P SPECC1L
nsv528009	Chr.22:24219538 - 24247641 on Build GRCh38	Loss	GGT5
esv2724041	Chr.22:23315914 - 24669376 on Build GRCh38	Deletion	SLC2A11 LOC100652871 LOC107985555 GSTTP1 ADORA2A DDTL BCR GSTT2 SNRPD3 CABIN1 ZNF70 MIF-AS1 LOC107985559 LOC101929374 VPREB3 BCRP3 CES5AP1 GGT1 MIF RGL4 MMP11 POM121L9P DDT UPB1 SMARCB1 DRICH1 CHCHD10 GGT5 SPECC1L-ADORA2A PCAT14 LRRC75B ZDHHC8P1 ADORA2A-AS1 GSTT2B SPECC1L GUCD1 LOC388882 IGLL1 GUSBP11 POM121L10P DERL3 C22orf15 SUSD2
nsv526567	Chr.22:23348138 - 24600663 on Build GRCh38	Gain	SLC2A11 LOC100652871 LOC107985555 GSTTP1 ADORA2A DDTL GSTT2 SNRPD3 CABIN1 ZNF70 MIF-AS1 LOC107985559 LOC101929374 VPREB3 CES5AP1 GGT1 MIF RGL4 MMP11 POM121L9P DDT UPB1 SMARCB1 DRICH1 CHCHD10 GGT5 SPECC1L-ADORA2A PCAT14 LRRC75B ZDHHC8P1 ADORA2A-AS1 GSTT2B SPECC1L GUCD1 LOC388882 IGLL1 GUSBP11 DERL3 C22orf15 SUSD2
esv3893463	Chr.22:24009046 - 24601506 on Build GRCh38	Gain	UPB1 GGT5 SPECC1L-ADORA2A LRRC75B ADORA2A ADORA2A-AS1 SNRPD3 SPECC1L GUCD1 CABIN1 GGT1 SUSD2 POM121L9P
dgv4528n100	Chr.22:23322244 - 24682765 on Build GRCh38	Gain	SLC2A11 LOC100652871 LOC107985555 GSTTP1 ADORA2A DDTL GSTT2 SNRPD3 CABIN1 ZNF70 MIF-AS1 LOC107985559 LOC101929374 VPREB3 BCRP3 CES5AP1 GGT1 MIF RGL4 MMP11 POM121L9P DDT UPB1 SMARCB1 DRICH1 CHCHD10 GGT5 SPECC1L-ADORA2A PCAT14 LRRC75B ZDHHC8P1 ADORA2A-AS1 GSTT2B SPECC1L GUCD1 LOC388882 IGLL1 GUSBP11 POM121L10P DERL3 C22orf15 SUSD2
nsv953059	Chr.22:24214433 - 24259032 on Build GRCh38	Deletion	GGT5 POM121L9P
esv3575443	Chr.22:23348201 - 24670505 on Build GRCh38	Gain	SLC2A11 LOC100652871 LOC107985555 GSTTP1 ADORA2A DDTL GSTT2 SNRPD3 CABIN1 ZNF70 MIF-AS1 LOC107985559 LOC101929374 VPREB3 BCRP3 CES5AP1 GGT1 MIF RGL4 MMP11 POM121L9P DDT UPB1 SMARCB1 DRICH1 CHCHD10 GGT5 SPECC1L-ADORA2A PCAT14 LRRC75B ZDHHC8P1 ADORA2A-AS1 GSTT2B SPECC1L GUCD1 LOC388882 IGLL1 GUSBP11 POM121L10P DERL3 C22orf15 SUSD2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

proteolysis
cellular amino acid metabolic process
leukotriene metabolic process
glutathione metabolic process
glutathione biosynthetic process
inflammatory response
leukotriene biosynthetic process

Function(s)

gamma-glutamyltransferase activity
glutathione hydrolase activity