Hs01257459_cn

• Gene Symbol: MARCH8
• Assay Reference Genome Location: Chr.10:45457934 on build GRCh38
• Cytoband: 10q11.21

Target Gene Details

• Entrez Gene ID: 220972
• Gene Name: membrane associated ring-CH-type finger 8
• Gene Aliases: CMIR, MARCH-VIII, MIR, RNF178, c-MIR
• Location: Chr.10:45454585-45594907 on Build GRCh38
• Assay Gene Location: Within Exon 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MARCH8	NM_001002266.2	7	1443	NP_001002266.1
	NM_001282866.1	8	2289	NP_001269795.1
	NM_145021.5	7	1931	NP_659458.2
	XM_005271804.2	8	2778	XP_005271861.1
	XM_006717704.2	8	2193	XP_006717767.1
	XM_011539492.2	9	2829	XP_011537794.1
	XM_011539493.2	10	3070	XP_011537795.1
	XM_011539494.2	9	3019	XP_011537796.1
	XM_011539495.1	7	1327	XP_011537797.1
	XM_017015894.1	8	1983	XP_016871383.1
	AK023636.1	3	1732
	AK057289.1	7	1637
	AL833316.1	4	1674
	BC025394.2	7	1420	AAH25394.1
	BC066988.1	7	1932	AAH66988.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1043536	Chr.10:45420493 - 45580787 on Build GRCh38	Gain	LOC102724323 MARCH8 ALOX5
esv3891797	Chr.10:45008026 - 45674466 on Build GRCh38	Gain	MIR3156-1 RSU1P2 ANKRD30BP3 LOC102724323 ZFAND4 OR13A1 MARCH8 ALOX5

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

protein polyubiquitination
adaptive immune response
antigen processing and presentation of peptide antigen via MHC class II
negative regulation of MHC class II biosynthetic process

Function(s)

ubiquitin-protein transferase activity
zinc ion binding
ligase activity
MHC class II protein binding
ubiquitin protein ligase activity