Hs01378109_cn

• Gene Symbol: PBK
• Assay Reference Genome Location: Chr.8:27833138 on build GRCh38
• Cytoband: 8p21.1

Target Gene Details

• Entrez Gene ID: 55872
• Gene Name: PDZ binding kinase
• Gene Aliases: CT84, HEL164, Nori-3, SPK, TOPK
• Location: Chr.8:27809621-27838095 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PBK	NM_001278945.1			NP_001265874.1
	NM_018492.3			NP_060962.2
	XM_006716368.2			XP_006716431.1
	AB027249.1			BAA99576.1
	AB027250.1			BAA99577.1
	AF189722.1			AAF69107.1
	AF237709.1			AAF71521.1
	AK027291.1			BAB55019.1
	AK301836.1
	BC015191.1			AAH15191.1
	BI461026.1
	DB028500.1
	EU794685.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv524133	Chr.8:27776547 - 27858791 on Build GRCh38	Loss	ESCO2 PBK

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

protein phosphorylation
mitotic nuclear division
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of stress-activated MAPK cascade
cellular response to UV
negative regulation of inflammatory response

Function(s)

protein serine/threonine kinase activity
protein binding
ATP binding