Hs01451269_cn

• Gene Symbol: EXOC3
• Assay Reference Genome Location: Chr.5:447588 on build GRCh38
• Cytoband: 5p15.33

Target Gene Details

• Entrez Gene ID: 11336
• Gene Name: exocyst complex component 3
• Gene Aliases: SEC6, SEC6L1, Sec6p
• Location: Chr.5:443184-471938 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXOC3	NM_007277.4	3	328	NP_009208.2
	XM_011513948.2	3	363	XP_011512250.1
	XM_011513949.2	3	380	XP_011512251.1
	XM_011513950.2	2	258	XP_011512252.1
	XM_011513951.2	3	357	XP_011512253.1
	XM_017009000.1	3	363	XP_016864489.1
	XM_017009001.1	3	363	XP_016864490.1
	XM_017009002.1	3	363	XP_016864491.1
	XM_017009003.1	3	363	XP_016864492.1
	XM_017009004.1	4	441	XP_016864493.1
	XM_017009005.1	3	357	XP_016864494.1
	XM_017009006.1	3	357	XP_016864495.1
	AK074086.1	2	319	BAB84912.1
	AL545132.3	3	361
	AL832434.1			CAH10613.1
	BC064569.1	2	270	AAH64569.1
	GU727644.1	3	328

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3894107	Chr.5:81322 - 801057 on Build GRCh38	Gain	PP7080 SDHA TPPP LOC101929895 AHRR MIR4456 EXOC3 CEP72 ZDHHC11B PDCD6 PLEKHG4B LOC100996325 HRAT5 SLC9A3 LRRC14B EXOC3-AS1 CCDC127 LOC100288152 ZDHHC11
nsv830183	Chr.5:349237 - 502409 on Build GRCh38	Gain+Loss	AHRR EXOC3 PP7080 SLC9A3 EXOC3-AS1 LOC100288152
nsv1032584	Chr.5:375290 - 809679 on Build GRCh38	Gain	PP7080 TPPP LOC101929895 AHRR MIR4456 EXOC3 CEP72 ZDHHC11B LOC100996325 SLC9A3 EXOC3-AS1 LOC100288152 ZDHHC11
nsv461889	Chr.5:429874 - 598109 on Build GRCh38	Gain	AHRR MIR4456 EXOC3 PP7080 SLC9A3 EXOC3-AS1 LOC100288152
nsv1030767	Chr.5:154674 - 457840 on Build GRCh38	Gain	AHRR EXOC3 PDCD6 PLEKHG4B HRAT5 SDHA LRRC14B EXOC3-AS1 CCDC127
dgv9479n54	Chr.5:438449 - 567131 on Build GRCh38	Gain	MIR4456 EXOC3 PP7080 SLC9A3 EXOC3-AS1 LOC100288152
esv2759315	Chr.5:17263 - 595840 on Build GRCh38	Loss	PP7080 SDHA AHRR MIR4456 EXOC3 PDCD6 PLEKHG4B HRAT5 SLC9A3 LRRC14B EXOC3-AS1 CCDC127 LOC100288152
nsv1032824	Chr.5:335214 - 449516 on Build GRCh38	Gain	AHRR EXOC3 EXOC3-AS1
esv3603744	Chr.5:359572 - 478120 on Build GRCh38	Gain	AHRR EXOC3 PP7080 SLC9A3 EXOC3-AS1 LOC100288152
nsv4673	Chr.5:414170 - 449449 on Build GRCh38	Insertion	AHRR EXOC3 EXOC3-AS1
nsv1027279	Chr.5:337575 - 531110 on Build GRCh38	Gain	AHRR EXOC3 PP7080 SLC9A3 EXOC3-AS1 LOC100288152
nsv1019215	Chr.5:346521 - 661696 on Build GRCh38	Gain	AHRR MIR4456 EXOC3 CEP72 LOC100996325 PP7080 SLC9A3 TPPP EXOC3-AS1 LOC100288152
esv2752071	Chr.5:378298 - 699075 on Build GRCh38	Gain	AHRR MIR4456 EXOC3 CEP72 LOC100996325 PP7080 SLC9A3 TPPP EXOC3-AS1 LOC101929895 LOC100288152
nsv830184	Chr.5:378153 - 451752 on Build GRCh38	Gain	AHRR EXOC3 EXOC3-AS1
esv3603745	Chr.5:376684 - 458243 on Build GRCh38	Gain	AHRR EXOC3 EXOC3-AS1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane traffic protein

Gene Ontology Categories:

Process(es)

exocytosis
protein transport
exocyst localization
cell-cell adhesion

Function(s)

SNARE binding
protein binding
cadherin binding involved in cell-cell adhesion