Hs01467476_cn

• Gene Symbol: PPP1R16A
• Assay Reference Genome Location: Chr.8:144497458 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 84988
• Gene Name: protein phosphatase 1 regulatory subunit 16A
• Gene Aliases: MYPT3
• Location: Chr.8:144477987-144502121 on Build GRCh38
• Assay Gene Location: Overlaps Exon 5 - Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPP1R16A	XM_005272350.2			XP_005272407.1
	XM_011517349.2			XP_011515651.1
	XM_017013912.1			XP_016869401.1
	XM_017013913.1			XP_016869402.1
	XM_017013914.1			XP_016869403.1
	XM_017013915.1			XP_016869404.1
	AK090471.1	4	1132	BAC03452.1
	BC007854.2			AAH07854.1
	BC049841.1			AAH49841.1
	BC053506.1			AAH53506.1
	BT006845.1			AAP35491.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	CPSF1 LOC101928902 MIR6848 HGH1 HSF1 CYHR1 LOC101928953 SPATC1 SLC39A4 RECQL4 MIR6849 EXOSC4 OPLAH SLC52A2 MFSD3 FOXH1 PPP1R16A SCRT1 KIFC2 SHARPIN MAF1 MIR661 GPT WDR97 SMPD5 MROH1 MIR1234 DGAT1 ADCK5 TMEM249 PLEC MIR6847 GRINA MIR6893 MIR7112 LRRC14 TONSL-AS1 CYC1 PARP10 MIR939 MIR6846 GPAA1 FBXL6 BOP1 TONSL VPS28 SCX
nsv612951	Chr.8:144479830 - 144677692 on Build GRCh38	Loss	GPT LOC101928953 ARHGAP39 RECQL4 MFSD3 C8orf82 PPP1R16A LRRC14 LRRC24
nsv831489	Chr.8:144342140 - 144544026 on Build GRCh38	Loss	CPSF1 LOC101928902 CYHR1 LOC101928953 SLC39A4 RECQL4 MIR6849 SLC52A2 MFSD3 FOXH1 C8orf82 PPP1R16A KIFC2 GPT MIR1234 ADCK5 TMEM249 ARHGAP39 MIR6893 LRRC14 LRRC24 TONSL-AS1 MIR939 FBXL6 TONSL VPS28
dgv12439n54	Chr.8:144438306 - 144525122 on Build GRCh38	Loss	TONSL-AS1 GPT CYHR1 LOC101928953 RECQL4 MFSD3 FOXH1 PPP1R16A KIFC2 TONSL LRRC14 LRRC24
nsv612955	Chr.8:144494912 - 144502322 on Build GRCh38	Loss	GPT LOC101928953 PPP1R16A
nsv482126	Chr.8:144496726 - 144502120 on Build GRCh38	Gain	LOC101928953 PPP1R16A
dgv907n27	Chr.8:144416180 - 144525122 on Build GRCh38	Loss	CYHR1 LOC101928953 SLC39A4 RECQL4 MFSD3 FOXH1 PPP1R16A MIR6893 KIFC2 LRRC14 LRRC24 TONSL-AS1 GPT TONSL VPS28
dgv12434n54	Chr.8:144270080 - 144516801 on Build GRCh38	Loss	CPSF1 LOC101928902 MIR6848 HSF1 CYHR1 LOC101928953 SLC39A4 RECQL4 MIR6849 SLC52A2 MFSD3 FOXH1 PPP1R16A SCRT1 KIFC2 GPT MIR1234 DGAT1 ADCK5 TMEM249 MIR6893 TONSL-AS1 MIR939 FBXL6 BOP1 TONSL VPS28
dgv12442n54	Chr.8:144492696 - 144516381 on Build GRCh38	Loss	GPT LOC101928953 RECQL4 MFSD3 PPP1R16A
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	CPSF1 LOC101928902 MIR6848 HGH1 HSF1 CYHR1 LOC101928953 SPATC1 SLC39A4 RECQL4 MIR6849 EXOSC4 OPLAH SLC52A2 MFSD3 FOXH1 PPP1R16A SCRT1 KIFC2 SHARPIN MAF1 MIR661 GPT WDR97 SMPD5 MROH1 MIR1234 DGAT1 ADCK5 TMEM249 PLEC MIR6847 GRINA MIR6893 MIR7112 LRRC14 TONSL-AS1 CYC1 PARP10 MIR939 MIR6846 GPAA1 FBXL6 BOP1 TONSL VPS28 SCX
nsv612940	Chr.8:144436292 - 144613673 on Build GRCh38	Loss	CYHR1 LOC101928953 ARHGAP39 RECQL4 MFSD3 FOXH1 C8orf82 PPP1R16A KIFC2 LRRC14 LRRC24 TONSL-AS1 GPT TONSL
nsv428208	Chr.8:144041826 - 144722291 on Build GRCh38	Gain	CPSF1 LOC101928902 MIR6848 HGH1 HSF1 CYHR1 LOC101928953 SPATC1 SLC39A4 RECQL4 MIR6849 EXOSC4 OPLAH SLC52A2 MFSD3 FOXH1 C8orf82 PPP1R16A SCRT1 KIFC2 SHARPIN MAF1 GPT ZNF251 WDR97 SMPD5 MROH1 MIR1234 DGAT1 ADCK5 TMEM249 ARHGAP39 MIR6847 MIR6893 MIR7112 LRRC14 LRRC24 TONSL-AS1 CYC1 MIR939 MIR6846 GPAA1 FBXL6 BOP1 TONSL VPS28 SCX
esv29999	Chr.8:144456732 - 144525122 on Build GRCh38	Loss	GPT CYHR1 LOC101928953 RECQL4 MFSD3 FOXH1 PPP1R16A KIFC2 LRRC14 LRRC24

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphatase modulator

Gene Ontology Categories:

Process(es)

regulation of catalytic activity

Function(s)

protein binding
protein phosphatase type 1 regulator activity