Hs01494717_cn

• Gene Symbol: ADCYAP1
• Assay Reference Genome Location: Chr.18:910165 on build GRCh38
• Cytoband: 18p11.32

Target Gene Details

• Entrez Gene ID: 116
• Gene Name: adenylate cyclase activating polypeptide 1
• Gene Aliases: PACAP
• Location: Chr.18:904342-912172 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADCYAP1	NM_001099733.1	5	1180	NP_001093203.1
	NM_001117.4	4	1252	NP_001108.2
	XM_005258081.3	6	1579	XP_005258138.1
	S83513.1	4	1062	AAB21470.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv517252	Chr.18:902327 - 910634 on Build GRCh38	Loss	ADCYAP1
dgv5810n54	Chr.18:351004 - 2238246 on Build GRCh38	Gain	TYMSOS CETN1 COLEC12 LOC388456 YES1 LOC105376854 CLUL1 ADCYAP1 TYMS LINC00470 ENOSF1
nsv528169	Chr.18:551688 - 2240220 on Build GRCh38	Loss	TYMSOS CETN1 LOC388456 YES1 CLUL1 ADCYAP1 TYMS LINC00470 ENOSF1
dgv5811n54	Chr.18:841320 - 1798153 on Build GRCh38	Gain	LOC388456 ADCYAP1 LINC00470
nsv482935	Chr.18:10001 - 2900002 on Build GRCh38	Loss	TYMSOS LOC101926997 COLEC12 LOC388456 YES1 LOC105376854 THOC1 CBX3P2 TYMS LINC00470 ENOSF1 METTL4 ROCK1P1 CETN1 USP14 EMILIN2 SMCHD1 CLUL1 ADCYAP1 MIR8078 NDC80
nsv576228	Chr.18:69836 - 1506323 on Build GRCh38	Loss	TYMSOS COLEC12 LOC388456 YES1 LOC105376854 THOC1 TYMS LINC00470 ENOSF1 ROCK1P1 CETN1 USP14 CLUL1 ADCYAP1 MIR8078

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

neuropeptide

Gene Ontology Categories:

Process(es)

ovarian follicle development
behavioral fear response
histamine secretion
negative regulation of acute inflammatory response to antigenic stimulus
negative regulation of acute inflammatory response to non-antigenic stimulus
activation of adenylate cyclase activity
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
cell-cell signaling
female pregnancy
regulation of G-protein coupled receptor protein signaling pathway
positive regulation of cell proliferation
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
negative regulation of muscle cell apoptotic process
positive regulation of neuron projection development
sensory perception of pain
cAMP-mediated signaling
pituitary gland development
neuron projection development
positive regulation of interleukin-6 production
regulation of protein localization
negative regulation of GTPase activity
response to starvation
negative regulation of potassium ion transport
positive regulation of GTPase activity
response to ethanol
negative regulation of cell cycle
positive regulation of protein kinase activity
positive regulation of vasodilation
positive regulation of transcription from RNA polymerase II promoter
ATP metabolic process
positive regulation of synaptic transmission, glutamatergic
regulation of postsynaptic membrane potential
positive regulation of growth hormone secretion
negative regulation of glial cell proliferation
positive regulation of ERK1 and ERK2 cascade
regulation of oligodendrocyte progenitor proliferation
cellular response to glucocorticoid stimulus
positive regulation of chemokine (C-C motif) ligand 5 production
positive regulation of somatostatin secretion

Function(s)

receptor signaling protein activity
receptor binding
neuropeptide hormone activity
protein binding
pituitary adenylate cyclase activating polypeptide activity
pituitary adenylate cyclase-activating polypeptide receptor binding
peptide hormone receptor binding