Hs01497002_cn

• Gene Symbol: OLIG2
• Assay Reference Genome Location: Chr.21:33028685 on build GRCh38
• Cytoband: 21q22.11

Target Gene Details

• Entrez Gene ID: 10215
• Gene Name: oligodendrocyte lineage transcription factor 2
• Gene Aliases: BHLHB1, OLIGO2, PRKCBP2, RACK17, bHLHe19
• Location: Chr.21:33025908-33029196 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
OLIG2	NM_005806.3	2	2004	NP_005797.1
	XM_005260908.1	2	2211	XP_005260965.1
	AF221520.1	2	1927	AAF61215.1
	AK091462.1	1	2751
	BC036245.1	1	2751	AAH36245.1
	BC047511.1	2	1977	AAH47511.1
	U48250.1	1	1857	AAC72247.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv520925	Chr.21:33021637 - 33033627 on Build GRCh38	Loss	OLIG2

More Information

Additional Information:

• Set Membership: Intragenic, Exonic, DGV Variation, Validated

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
spinal cord motor neuron differentiation
spinal cord oligodendrocyte cell fate specification
thalamus development
myelination
negative regulation of neuron differentiation
neuron fate commitment
positive regulation of oligodendrocyte differentiation

Function(s)

DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein homodimerization activity
HMG box domain binding