Hs01508409_cn

• Gene Symbol: CLDN22
• Assay Reference Genome Location: Chr.4:183318577 on build GRCh38
• Cytoband: 4q35.1

Target Gene Details

• Entrez Gene ID: 53842
• Gene Name: claudin 22
• Gene Aliases: CLDN21
• Location: Chr.4:183318067-183320774 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CLDN22	NM_001111319.1	1	2198	NP_001104789.1
	AK098064.1	1	1592

Target Gene Details

• Entrez Gene ID: 80014
• Gene Name: WW and C2 domain containing 2
• Gene Aliases: BOMB
• Location: Chr.4:183098677-183320777 on Build GRCh38
• Assay Gene Location: Within Exon 23

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
WWC2	NM_024949.5	23	6609	NP_079225.5
	XM_011532269.2			XP_011530571.1
	AK091401.1	1	384
	AL832424.1	3	3234	CAH10641.1
	BX647378.1	21	6200	CAH10569.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1030766	Chr.4:183305034 - 183948875 on Build GRCh38	Gain	RWDD4 LOC389247 WWC2 STOX2 LOC107986217 CLDN22 LOC101929996 CLDN24 ING2 TRAPPC11 CDKN2AIP
nsv1029647	Chr.4:183268304 - 183372226 on Build GRCh38	Gain	WWC2 LOC107986217 CLDN22 CLDN24

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

tight junction

Gene Ontology Categories:

Process(es)

calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
negative regulation of transcription from RNA polymerase II promoter
negative regulation of hippo signaling
negative regulation of organ growth

Function(s)

structural molecule activity
identical protein binding
kinase binding
protein complex scaffold