Hs01532797_cn

• Gene Symbol: CDT1
• Assay Reference Genome Location: Chr.16:88806679 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 81620
• Gene Name: chromatin licensing and DNA replication factor 1
• Gene Aliases: DUP, RIS2
• Location: Chr.16:88803778-88809258 on Build GRCh38
• Assay Gene Location: Overlaps Exon 7 - Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDT1	NM_030928.3			NP_112190.2
	AB053172.1			BAB61878.1
	AF070552.1
	AF321125.1			AAG45181.1
	BC000137.2			AAH00137.2
	BC008676.1			AAH08676.1
	BC008860.2			AAH08860.2
	BC009410.1			AAH09410.1
	BC014202.2			AAH14202.2
	BC021126.1
	BC049205.1			AAH49205.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	ZNF778 LOC101927793 LOC105371409 SLC22A31 TRAPPC2L CDT1 PABPN1L LOC400558 CBFA2T3 PIEZO1 LOC107987238 APRT LOC339059 LINC00304 LOC100289580 LOC100129697 MIR4722 CTU2 GALNS CDH15 ACSF3
nsv457617	Chr.16:88801844 - 88829729 on Build GRCh38	Gain	LOC107987238 APRT CDT1 GALNS
dgv3064n100	Chr.16:88683753 - 88846491 on Build GRCh38	Gain	SNAI3-AS1 LOC107987238 SNAI3 APRT LOC339059 CDT1 LOC100289580 RNF166 MIR4722 CTU2 GALNS PIEZO1
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	ZNF778 LOC101927793 LOC105371409 SLC22A31 TRAPPC2L CDT1 ANKRD11 PABPN1L LOC400558 CBFA2T3 PIEZO1 LOC105371414 LOC107987238 APRT LOC339059 LOC100287036 LINC00304 LOC100289580 LOC100129697 GALNS CDH15 ACSF3
nsv952071	Chr.16:88790893 - 89019992 on Build GRCh38	Deletion	LOC107987238 LOC101927793 LOC105371409 APRT TRAPPC2L CDT1 LOC100129697 PABPN1L CBFA2T3 GALNS
nsv521217	Chr.16:88805821 - 89174375 on Build GRCh38	Loss	LOC101927793 LOC105371409 TRAPPC2L CDT1 PABPN1L LOC400558 CBFA2T3 LOC107987238 APRT LINC00304 LOC100129697 GALNS CDH15 ACSF3
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	DEF8 RPL13 TUBB3 TCF25 SLC22A31 RNF166 GAS8 CBFA2T3 PIEZO1 DBNDD1 SPIRE2 LOC100289580 CENPBD1 SPATA33 VPS9D1 LOC101927793 CDT1 TUBB8P7 PABPN1L CYBA FAM157C LOC107987238 APRT PRDM7 LINC00304 MIR4722 CTU2 GALNS AFG3L1P URAHP CPNE7 CHMP1A LOC105371409 TRAPPC2L LOC101927817 LOC105371419 ANKRD11 LOC400558 FANCA VPS9D1-AS1 MC1R LOC339059 SPATA2L SPG7 GAS8-AS1 CDH15 ACSF3 DPEP1 SNAI3-AS1 MVD ZNF778 SNAI3 LOC105371414 ZNF276 IL17C CDK10 LOC100287036 LOC107984817 LOC100129697 SNORD68
nsv1063441	Chr.16:88767066 - 88861882 on Build GRCh38	Loss	LOC107987238 APRT TRAPPC2L CDT1 GALNS PIEZO1
dgv37n68	Chr.16:88767460 - 88944903 on Build GRCh38	Loss	LOC107987238 LOC101927793 LOC105371409 APRT TRAPPC2L CDT1 LOC100129697 PABPN1L CBFA2T3 GALNS PIEZO1
esv3639555	Chr.16:88745961 - 88899576 on Build GRCh38	Gain	LOC107987238 LOC101927793 APRT TRAPPC2L CDT1 PABPN1L CBFA2T3 GALNS PIEZO1
nsv573715	Chr.16:88804814 - 88808224 on Build GRCh38	Loss	CDT1
nsv1061256	Chr.16:88711587 - 89013365 on Build GRCh38	Gain	LOC101927793 LOC105371409 TRAPPC2L CDT1 PABPN1L CBFA2T3 PIEZO1 LOC107987238 APRT LOC339059 LOC100289580 LOC100129697 MIR4722 CTU2 GALNS
nsv573712	Chr.16:88796728 - 88809084 on Build GRCh38	Loss	CDT1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

DNA replication checkpoint
G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
DNA replication
regulation of DNA-dependent DNA replication initiation
regulation of nuclear cell cycle DNA replication

Function(s)

DNA binding
protein binding