Hs01534338_cn

• Gene Symbol: GLUL
• Assay Reference Genome Location: Chr.1:182384022 on build GRCh38
• Cytoband: 1q25.3

Target Gene Details

• Entrez Gene ID: 2752
• Gene Name: glutamate-ammonia ligase
• Gene Aliases: GLNS, GS, PIG43, PIG59
• Location: Chr.1:182378093-182392206 on Build GRCh38
• Assay Gene Location: Within Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GLUL	NM_001033044.3	7	2046	NP_001028216.1
	NM_001033056.3	7	1748	NP_001028228.1
	NM_002065.6	8	2402	NP_002056.2
	XM_006711278.1	7	2109	XP_006711341.1
	AK301600.1	2	928
	AL161952.1	2	3867	CAB82304.1
	AY947343.1	7	1606
	BC011700.2	7	1614	AAH11700.1
	BC011852.2	7	1625	AAH11852.1
	BC018992.1	8	1965	AAH18992.1
	BC051726.1	7	2811	AAH51726.1
	BX537384.1	7	1630	CAD97626.1
	S70290.1	6	1505	AAB30693.1
	X59834.1	7	1614	CAA42495.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv946532	Chr.1:182384061 - 182385635 on Build GRCh38	Duplication	GLUL
nsv548358	Chr.1:182110851 - 183151893 on Build GRCh38	Gain	LOC647070 RGS8 NPL DHX9 TEDDM1 LAMC1 RNASEL LOC284648 ZNF648 SHCBP1L GLUL LINC00272 LOC105371644 LINC01344 RGSL1 RGS16

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

ligase

Gene Ontology Categories:

Process(es)

neurotransmitter uptake
glutamate catabolic process
glutamine biosynthetic process
cell proliferation
cellular amino acid biosynthetic process
cellular response to starvation
response to glucose
ammonia assimilation cycle
positive regulation of insulin secretion
positive regulation of epithelial cell proliferation
protein homooligomerization
positive regulation of synaptic transmission, glutamatergic

Function(s)

magnesium ion binding
glutamate decarboxylase activity
glutamate-ammonia ligase activity
protein binding
ATP binding
glutamate binding
manganese ion binding
identical protein binding
dynein light chain binding