Hs01554627_cn

• Gene Symbol: THRA
• Assay Reference Genome Location: Chr.17:40074355 on build GRCh38
• Cytoband: 17q21.1

Target Gene Details

• Entrez Gene ID: 7067
• Gene Name: thyroid hormone receptor, alpha
• Gene Aliases: AR7, CHNG6, EAR7, ERB-T-1, ERBA, ERBA1, NR1A1, THRA1, THRA2, c-ERBA-1
• Location: Chr.17:40062193-40093867 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
THRA	NM_001190918.1	2	442	NP_001177847.1
	NM_001190919.1	2	423	NP_001177848.1
	NM_003250.5	2	442	NP_003241.2
	NM_199334.3	2	442	NP_955366.1
	AB209346.1	2	492	BAD92583.1
	AK290071.1	2	269
	AK290530.1	2	423
	AK311344.1	2	217
	BC000261.1	2	291	AAH00261.1
	BC002728.2	2	291	AAH02728.1
	BC008851.2	2	513
	BC035137.1	2	451	AAH35137.1
	M24899.1	2	278	AAA35783.1
	X55005.1	2	333	CAA38749.1
	Y00479.1	2	202	CAA68539.1

More Information

• Set Membership: Intragenic, Exonic, non-DGV Variation

Panther Classification:

Molecular Function -

C4 zinc finger nuclear receptor, DNA-binding transcription factor, zinc finger transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

cartilage condensation
ossification
kidney development
liver development
regulation of thyroid hormone mediated signaling pathway
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
brain development
learning or memory
regulation of heart contraction
female courtship behavior
response to cold
hormone-mediated signaling pathway
positive regulation of myotube differentiation
negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
erythrocyte differentiation
adrenal gland development
intracellular receptor signaling pathway
thyroid gland development
response to nutrient levels
regulation of myeloid cell apoptotic process
response to drug
cytoplasmic sequestering of transcription factor
steroid hormone mediated signaling pathway
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of transcription, DNA-templated
positive regulation of female receptivity
positive regulation of transcription from RNA polymerase II promoter
digestive tract development
embryonic organ development
regulation of lipid catabolic process
Type I pneumocyte differentiation
negative regulation of DNA-templated transcription, initiation

Function(s)

transcription regulatory region sequence-specific DNA binding
steroid receptor RNA activator RNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
steroid hormone receptor activity
thyroid hormone receptor activity
protein binding
transcription factor binding
zinc ion binding
TBP-class protein binding
protein domain specific binding
chromatin DNA binding
protein complex binding
protein homodimerization activity
transcription regulatory region DNA binding
intronic transcription regulatory region DNA binding
protein heterodimerization activity
thyroid hormone binding