Hs01619777_cn

• Gene Symbol: CDT1
• Assay Reference Genome Location: Chr.16:88807472 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 81620
• Gene Name: chromatin licensing and DNA replication factor 1
• Gene Aliases: DUP, RIS2
• Location: Chr.16:88803778-88809258 on Build GRCh38
• Assay Gene Location: Overlaps Exon 9 - Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDT1	NM_030928.3			NP_112190.2
	AB053172.1			BAB61878.1
	AF070552.1
	AF321125.1			AAG45181.1
	BC000137.2			AAH00137.2
	BC008676.1			AAH08676.1
	BC008860.2			AAH08860.2
	BC009410.1			AAH09410.1
	BC014202.2			AAH14202.2
	BC021126.1
	BC049205.1			AAH49205.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	LINC00304 PABPN1L CDT1 LOC105371409 SLC22A31 ZNF778 APRT LOC400558 LOC100129697 CDH15 PIEZO1 LOC339059 CBFA2T3 LOC107987238 LOC100289580 LOC101927793 GALNS ACSF3 MIR4722 TRAPPC2L CTU2
nsv457617	Chr.16:88801844 - 88829729 on Build GRCh38	Gain	CDT1 LOC107987238 APRT GALNS
dgv3064n100	Chr.16:88683753 - 88846491 on Build GRCh38	Gain	SNAI3-AS1 PIEZO1 LOC339059 SNAI3 CDT1 RNF166 LOC107987238 LOC100289580 APRT GALNS MIR4722 CTU2
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	LOC105371414 LINC00304 PABPN1L CDT1 LOC105371409 SLC22A31 ZNF778 ANKRD11 APRT LOC400558 LOC100129697 CDH15 PIEZO1 LOC339059 LOC100287036 CBFA2T3 LOC107987238 LOC100289580 LOC101927793 GALNS ACSF3 TRAPPC2L
nsv952071	Chr.16:88790893 - 89019992 on Build GRCh38	Deletion	LOC100129697 PABPN1L CDT1 LOC105371409 CBFA2T3 LOC107987238 LOC101927793 APRT GALNS TRAPPC2L
nsv521217	Chr.16:88805821 - 89174375 on Build GRCh38	Loss	LINC00304 PABPN1L CDT1 LOC105371409 APRT LOC400558 LOC100129697 CDH15 CBFA2T3 LOC107987238 LOC101927793 GALNS ACSF3 TRAPPC2L
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	TUBB8P7 LOC105371414 CDT1 VPS9D1-AS1 SLC22A31 ANKRD11 TUBB3 DEF8 SNAI3-AS1 SPG7 URAHP DBNDD1 LOC101927793 IL17C LINC00304 SPATA33 CPNE7 AFG3L1P GAS8-AS1 CDH15 TCF25 DPEP1 SPATA2L ACSF3 CDK10 PRDM7 MVD RPL13 FANCA LOC105371409 ZNF778 APRT LOC400558 LOC101927817 ZNF276 LOC100129697 PIEZO1 LOC339059 SNAI3 LOC100287036 CBFA2T3 LOC107984817 GALNS VPS9D1 MIR4722 TRAPPC2L FAM157C CHMP1A PABPN1L LOC105371419 RNF166 CENPBD1 GAS8 MC1R SPIRE2 SNORD68 LOC107987238 CYBA LOC100289580 CTU2
nsv1063441	Chr.16:88767066 - 88861882 on Build GRCh38	Loss	PIEZO1 CDT1 LOC107987238 APRT GALNS TRAPPC2L
dgv37n68	Chr.16:88767460 - 88944903 on Build GRCh38	Loss	LOC100129697 PIEZO1 PABPN1L CDT1 LOC105371409 CBFA2T3 LOC107987238 LOC101927793 APRT GALNS TRAPPC2L
nsv573718	Chr.16:88807259 - 88810716 on Build GRCh38	Loss	CDT1 APRT
esv3639555	Chr.16:88745961 - 88899576 on Build GRCh38	Gain	PIEZO1 PABPN1L CDT1 CBFA2T3 LOC107987238 LOC101927793 APRT GALNS TRAPPC2L
nsv573715	Chr.16:88804814 - 88808224 on Build GRCh38	Loss	CDT1
nsv1061256	Chr.16:88711587 - 89013365 on Build GRCh38	Gain	PABPN1L CDT1 LOC105371409 APRT LOC100129697 PIEZO1 LOC339059 CBFA2T3 LOC107987238 LOC100289580 LOC101927793 GALNS MIR4722 TRAPPC2L CTU2
nsv573712	Chr.16:88796728 - 88809084 on Build GRCh38	Loss	CDT1

More Information

Additional Information:

For this assay, SNP(s) [rs115396767] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

DNA replication checkpoint
G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
DNA replication
regulation of DNA-dependent DNA replication initiation
regulation of nuclear cell cycle DNA replication

Function(s)

DNA binding
protein binding