Hs01621704_cn

• Gene Symbol: FBXO36
• Assay Reference Genome Location: Chr.2:229922577 on build GRCh38
• Cytoband: 2q36.3

Target Gene Details

• Entrez Gene ID: 130888
• Gene Name: F-box protein 36
• Gene Aliases: Fbx36
• Location: Chr.2:229922491-230013109 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FBXO36	NM_174899.4	1	87	NP_777559.3
	AK123085.1	1	276
	AK289655.1	1	72
	AK309702.1	1	65
	BC033935.1	1	80	AAH33935.1
	BF674223.1	1	88

Target Gene Details

• Entrez Gene ID: 9320
• Gene Name: thyroid hormone receptor interactor 12
• Gene Aliases: TRIP-12, ULF
• Location: Chr.2:229763837-229923234 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRIP12	XM_011512181.2			XP_011510483.1
	XM_011512183.2			XP_011510485.1
	XM_017005274.1			XP_016860763.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv164e55	Chr.2:229802854 - 230128418 on Build GRCh38	Gain	TRIP12 FBXO36 SLC16A14
esv3594585	Chr.2:229856243 - 230039898 on Build GRCh38	Gain	TRIP12 FBXO36 SLC16A14
dgv7330n54	Chr.2:229859061 - 230036931 on Build GRCh38	Gain	TRIP12 FBXO36 SLC16A14
esv3575337	Chr.2:229849253 - 230039159 on Build GRCh38	Gain	TRIP12 FBXO36 SLC16A14
esv2751841	Chr.2:229710778 - 229964878 on Build GRCh38	Gain	DNER TRIP12 FBXO36
nsv1008431	Chr.2:229893749 - 230085172 on Build GRCh38	Gain	TRIP12 FBXO36 SLC16A14
nsv584650	Chr.2:229820254 - 230078735 on Build GRCh38	Gain	TRIP12 FBXO36 SLC16A14
dgv4179n100	Chr.2:229846823 - 230040510 on Build GRCh38	Gain	TRIP12 FBXO36 SLC16A14
nsv460118	Chr.2:229866681 - 230035049 on Build GRCh38	Gain	TRIP12 FBXO36 SLC16A14

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
protein polyubiquitination
DNA repair
cellular response to DNA damage stimulus
embryo development
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of histone H2A K63-linked ubiquitination
negative regulation of double-strand break repair

Function(s)

ubiquitin-protein transferase activity
protein binding
ligase activity
thyroid hormone receptor binding