Hs01704480_cn

• Gene Symbol: MARS
• Assay Reference Genome Location: Chr.12:57512771 on build GRCh38
• Cytoband: 12q13.3

Target Gene Details

• Entrez Gene ID: 4141
• Gene Name: methionyl-tRNA synthetase
• Gene Aliases: CMT2U, ILFS2, ILLD, METRS, MRS, MTRNS, SPG70
• Location: Chr.12:57487953-57516655 on Build GRCh38
• Assay Gene Location: Overlaps Intron 14 - Exon 15

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MARS	NM_004990.3			NP_004981.2
	XM_006719398.3			XP_006719461.1
	AK092986.1			BAC04011.1
	AK122956.1
	AK222767.1			BAD96487.1
	AK290857.1
	AK293945.1
	BC002384.2			AAH02384.1
	BC006328.2			AAH06328.1
	BC011639.2			AAH11639.1
	BC011849.2			AAH11849.1
	BC015011.1			AAH15011.1
	BT007338.1			AAP36002.1
	D84224.1			BAA95668.1
	X94754.1			CAA64381.1
	Z49216.1			CAA89153.1

Target Gene Details

• Entrez Gene ID: 102465454
• Gene Name: microRNA 6758
• Gene Aliases: hsa-mir-6758
• Location: Chr.12:57512688-57512750 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MIR6758	NR_106816.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759901	Chr.12:57435950 - 57608085 on Build GRCh38	Gain	MIR6758 ARHGAP9 DTX3 GLI1 DDIT3 PIP4K2C MBD6 MIR616 INHBE MARS INHBC DCTN2 KIF5A
nsv559034	Chr.12:57466149 - 57618450 on Build GRCh38	Loss	MIR6758 ARHGAP9 DTX3 GLI1 DDIT3 PIP4K2C MBD6 MIR616 MARS LOC101927583 DCTN2 KIF5A ARHGEF25
dgv2651n54	Chr.12:57450266 - 57552694 on Build GRCh38	Loss	MIR6758 INHBC ARHGAP9 GLI1 DDIT3 MBD6 DCTN2 MIR616 KIF5A INHBE MARS
nsv482992	Chr.12:56206217 - 57706217 on Build GRCh38	Gain+Loss	NACA RBMS2 GLI1 LRP1 RNF41 MIR616 INHBE RDH16 MARS SDR9C7 ATP5B HSD17B6 DCTN2 NABP2 SNORD59B NXPH4 PTGES3 MIR6758 STAT6 TIMELESS ANKRD52 ARHGAP9 MBD6 INHBC LOC101927583 MIP OS9 APOF SLC26A10 SNORA105C ARHGEF25 DDIT3 HBCBP STAT2 B4GALNT1 GLS2 ZBTB39 COQ10A SPRYD4 MYO1A NDUFA4L2 SNORD59A MIR1228 DTX3 SHMT2 IL23A PIP4K2C STAC3 SLC39A5 GPR182 CS R3HDM2 LRP1-AS NAB2 TAC3 PAN2 BAZ2A NEMP1 KIF5A CNPY2 PRIM1
esv3419248	Chr.12:57511702 - 57513300 on Build GRCh38	Duplication	MIR6758 MARS

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

aminoacyl-tRNA synthetase

Gene Ontology Categories:

Process(es)

tRNA aminoacylation for protein translation
methionyl-tRNA aminoacylation

Function(s)

tRNA binding
methionine-tRNA ligase activity
ATP binding