Hs01708495_cn

• Gene Symbol: BRAT1
• Assay Reference Genome Location: Chr.7:2542213 on build GRCh38
• Cytoband: 7p22.3

Target Gene Details

• Entrez Gene ID: 221927
• Gene Name: BRCA1 associated ATM activator 1
• Gene Aliases: BAAT1, C7orf27, RMFSL
• Location: Chr.7:2537810-2555758 on Build GRCh38
• Assay Gene Location: Overlaps Intron 7 - Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BRAT1	NM_152743.3			NP_689956.2
	XM_005249643.4			XP_005249700.1
	XM_011515177.2			XP_011513479.1
	XM_011515178.1			XP_011513480.1
	XM_011515179.2			XP_011513481.1
	XM_011515181.2			XP_011513483.1
	XM_011515182.2			XP_011513484.1
	XM_011515183.1			XP_011513485.1
	XM_011515184.2			XP_011513486.1
	XM_011515186.2			XP_011513488.1
	XM_017011833.1			XP_016867322.1
	XM_017011834.1			XP_016867323.1
	XM_017011835.1			XP_016867324.1
	XM_017011836.1			XP_016867325.1
	AK024482.1			BAB15772.1
	AK131083.1	5	2404	BAC85133.1
	AK131097.1	1	2040	BAC85147.1
	AK311144.1	2	452
	BC007209.1			AAH07209.1
	BC015632.2			AAH15632.2
	BC023561.2			AAH23561.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv823981	Chr.7:2507328 - 2543718 on Build GRCh38	Gain	LFNG BRAT1 MIR4648
nsv830887	Chr.7:2507249 - 2621396 on Build GRCh38	Loss	LFNG BRAT1 IQCE MIR4648
nsv950792	Chr.7:2418066 - 2544866 on Build GRCh38	Deletion	LOC101927181 LFNG BRAT1 MIR4648 GRIFIN CHST12
nsv605862	Chr.7:2516523 - 2604885 on Build GRCh38	Loss	LFNG BRAT1 IQCE MIR4648

More Information

Additional Information:

For this assay, SNP(s) [rs113638677,rs73287544] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
glucose metabolic process
apoptotic process
cellular response to DNA damage stimulus
cell proliferation
response to ionizing radiation
cell growth
cell migration
mitochondrion localization

Function(s)

protein binding