Hs01744116_cn

• Gene Symbol: THOC1
• Assay Reference Genome Location: Chr.18:214747 on build GRCh38
• Cytoband: 18p11.32

Target Gene Details

• Entrez Gene ID: 9984
• Gene Name: THO complex 1
• Gene Aliases: HPR1, P84, P84N5
• Location: Chr.18:214348-268059 on Build GRCh38
• Assay Gene Location: Within Exon 23

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
THOC1	NM_005131.2	21	1893	NP_005122.2
	XM_011525772.2	21	1914	XP_011524074.1
	XM_011525773.1	22	1944	XP_011524075.1
	XM_011525774.2	11	2485	XP_011524076.1
	XM_017026103.1	18	3434	XP_016881592.1
	AK055354.1	10	2564
	AK123530.1	8	2030
	AK225067.1	21	1869
	AK225709.1	21	1857
	AK314755.1	21	1859
	BC010381.1	21	1884	AAH10381.1
	L36529.1	21	1867	AAA53571.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv576227	Chr.18:52933 - 322183 on Build GRCh38	Gain	THOC1 MIR8078 USP14 COLEC12 ROCK1P1
esv3641475	Chr.18:153985 - 282924 on Build GRCh38	Gain	THOC1 USP14
nsv518642	Chr.18:196829 - 331506 on Build GRCh38	Gain	THOC1 USP14 COLEC12
nsv1064150	Chr.18:99036 - 321710 on Build GRCh38	Gain	THOC1 MIR8078 USP14 COLEC12 ROCK1P1
dgv3301n100	Chr.18:11543 - 326679 on Build GRCh38	Gain	THOC1 MIR8078 USP14 COLEC12 ROCK1P1
nsv1160503	Chr.18:200576 - 249255 on Build GRCh38	Duplication	THOC1 USP14
nsv482935	Chr.18:10001 - 2900002 on Build GRCh38	Loss	YES1 NDC80 TYMSOS ENOSF1 METTL4 LINC00470 MIR8078 USP14 LOC388456 CETN1 CBX3P2 COLEC12 EMILIN2 SMCHD1 THOC1 LOC105376854 TYMS LOC101926997 ADCYAP1 CLUL1 ROCK1P1
dgv3302n100	Chr.18:136228 - 249310 on Build GRCh38	Gain	THOC1 USP14
esv3641473	Chr.18:128077 - 323706 on Build GRCh38	Gain	THOC1 USP14 COLEC12
nsv576228	Chr.18:69836 - 1506323 on Build GRCh38	Loss	YES1 TYMSOS ENOSF1 LINC00470 MIR8078 USP14 LOC388456 CETN1 COLEC12 THOC1 LOC105376854 TYMS ADCYAP1 CLUL1 ROCK1P1
esv3573886	Chr.18:136227 - 218394 on Build GRCh38	Gain	THOC1 USP14

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

regulation of DNA recombination
termination of RNA polymerase II transcription
RNA processing
RNA export from nucleus
mRNA export from nucleus
apoptotic process
signal transduction
RNA splicing
mRNA 3'-end processing
replication fork processing
regulation of DNA-templated transcription, elongation
positive regulation of DNA-templated transcription, elongation
viral mRNA export from host cell nucleus
negative regulation of isotype switching to IgA isotypes
negative regulation of DNA damage checkpoint

Function(s)

DNA binding
RNA binding
protein binding