Hs01787767_cn

• Gene Symbol: NME3
• Assay Reference Genome Location: Chr.16:1770758 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 4832
• Gene Name: NME/NM23 nucleoside diphosphate kinase 3
• Gene Aliases: DR-nm23, NDPK-C, NDPKC, NM23-H3, NM23H3, c371H6.2
• Location: Chr.16:1770320-1771750 on Build GRCh38
• Assay Gene Location: Overlaps Intron 4 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NME3	NM_002513.2			NP_002504.2
	XM_005255332.4			XP_005255389.1
	XM_011522503.2			XP_011520805.1
	XM_011522504.2			XP_011520806.1
	AK308663.1
	BC000250.1			AAH00250.1
	BG911570.1
	U29656.1			AAA85097.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv457335	Chr.16:1729694 - 1789022 on Build GRCh38	Loss	EME2 NUBP2 MRPS34 MIR3177 MAPK8IP3 SPSB3 NME3
esv2422427	Chr.16:10001 - 2723164 on Build GRCh38	Duplication	NUBP2 ZNF598 LOC105371046 PIGQ SYNGR3 MEIOB MIR6767 TPSD1 HAGHL POLR3K NARFL SPSB3 LOC100134368 FAHD1 RPL3L NDUFB10 RHBDF1 GFER MIR3180-5 UBE2I MIR6511B1 SNRNP25 CLCN7 SNHG9 LOC105371047 MIR3178 FAM234A AMDHD2 MRPS34 MIR3177 PKD1 ABCA3 TBC1D24 MIR6859-4 CHTF18 MLST8 E4F1 MIR1225 WASIR2 SNORA10 TSR3 ARHGDIG ATP6V0C HBM TMEM8A LINC00254 MCRIP2 FLJ42627 MIR6768 RAB26 HBA1 TPSG1 C16orf59 LOC106660606 RPS2 PRR25 RPL23AP5 HAGH PTX4 METRN RHBDL1 SNHG19 RNF151 LMF1-AS1 HBA2 DECR2 ECI1 PRSS29P MSLN CCNF FAM173A MPG SSTR5-AS1 TSC2 DNASE1L2 CAPN15 MSRB1 JMJD8 LOC729652 RGS11 NME3 NTN3 MIR5587 UNKL PDPK1 TPSAB1 PDIA2 CEMP1 MRPL28 NPW RAB40C PRSS27 LUC7L EME2 KCTD5 TMEM204 SSTR5 HBZ ERVK13-1 MIR940 NHLRC4 RPUSD1 CASKIN1 LINC00235 TBL3 ABCA17P TRAF7 C16orf91 SNORD60 RNPS1 WDR90 GNPTG RHOT2 WFIKKN1 DDX11L10 FBXL16 WDR24 MIR4717 PGP PRR35 CRAMP1 SLC9A3R2 MIR3176 NPRL3 LOC107984876 TELO2 HN1L MIR4516 NME4 LOC105371045 IFT140 LOC105371038 AXIN1 TPSB2 LOC100287175 LOC101929280 BRICD5 C1QTNF8 LOC105371184 IGFALS SOX8 NOXO1 SNORA78 RAB11FIP3 CCDC78 STUB1 GNG13 LOC105371049 HBQ1 METTL26 MIR3677 HS3ST6 CCDC154 CACNA1H MAPK8IP3 LMF1 MIR662 NTHL1 SNORA64 LOC652276 BAIAP3 LOC107987233
esv3892756	Chr.16:1764390 - 1780436 on Build GRCh38	Loss	EME2 MRPS34 MAPK8IP3 SPSB3 NME3
nsv1160328	Chr.16:1704619 - 1797867 on Build GRCh38	Deletion	EME2 IGFALS NUBP2 MRPS34 MIR3177 MAPK8IP3 SPSB3 NME3
nsv571171	Chr.16:1757779 - 1804539 on Build GRCh38	Gain+Loss	EME2 IGFALS NUBP2 MRPS34 MAPK8IP3 SPSB3 NME3
dgv4856n54	Chr.16:1600945 - 1813519 on Build GRCh38	Loss	EME2 IGFALS NUBP2 CRAMP1 LOC105371046 HAGH NME3 HN1L MRPS34 MIR3177 IFT140 MAPK8IP3 SPSB3
nsv471069	Chr.16:1754356 - 1791032 on Build GRCh38	Loss	EME2 IGFALS NUBP2 MRPS34 MAPK8IP3 SPSB3 NME3
nsv1051692	Chr.16:1505070 - 1866102 on Build GRCh38	Loss	EME2 TMEM204 IGFALS NUBP2 CRAMP1 LOC105371046 HAGH MEIOB NME3 TELO2 HN1L LOC105371047 MRPS34 MIR3177 IFT140 MAPK8IP3 SPSB3 FAHD1
nsv827500	Chr.16:1761258 - 1795126 on Build GRCh38	Gain	EME2 IGFALS NUBP2 MRPS34 MAPK8IP3 SPSB3 NME3
nsv518641	Chr.16:1645775 - 1835631 on Build GRCh38	Loss	EME2 IGFALS NUBP2 CRAMP1 HAGH MEIOB NME3 HN1L MRPS34 MIR3177 MAPK8IP3 SPSB3 FAHD1
nsv571173	Chr.16:1767596 - 1780436 on Build GRCh38	Loss	EME2 MRPS34 MAPK8IP3 SPSB3 NME3
nsv952900	Chr.16:1724500 - 1827999 on Build GRCh38	Deletion	EME2 IGFALS NUBP2 MRPS34 MIR3177 MAPK8IP3 HAGH SPSB3 FAHD1 NME3
nsv571170	Chr.16:1752231 - 1791032 on Build GRCh38	Loss	EME2 IGFALS NUBP2 MRPS34 MAPK8IP3 SPSB3 NME3

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

purine nucleotide metabolic process
nucleoside diphosphate phosphorylation
GTP biosynthetic process
pyrimidine nucleotide metabolic process
UTP biosynthetic process
CTP biosynthetic process
apoptotic process
nucleoside triphosphate biosynthetic process
regulation of apoptotic process

Function(s)

nucleoside diphosphate kinase activity
protein binding
ATP binding
metal ion binding