Hs01787767_cn

• Gene Symbol: NME3
• Assay Reference Genome Location: Chr.16:1770758 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 4832
• Gene Name: NME/NM23 nucleoside diphosphate kinase 3
• Gene Aliases: DR-nm23, NDPK-C, NDPKC, NM23-H3, NM23H3, c371H6.2
• Location: Chr.16:1770320-1771750 on Build GRCh38
• Assay Gene Location: Overlaps Intron 4 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NME3	NM_002513.2			NP_002504.2
	XM_005255332.4			XP_005255389.1
	XM_011522503.2			XP_011520805.1
	XM_011522504.2			XP_011520806.1
	AK308663.1
	BC000250.1			AAH00250.1
	BG911570.1
	U29656.1			AAA85097.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv571169	Chr.16:1729694 - 1789022 on Build GRCh38	Loss	MRPS34 EME2 SPSB3 MAPK8IP3 NME3 MIR3177 NUBP2
esv2422427	Chr.16:10001 - 2723164 on Build GRCh38	Duplication	MLST8 METTL26 MIR3178 HAGHL RGS11 CEMP1 LOC101929280 POLR3K EME2 FAHD1 LOC100287175 ARHGDIG BRICD5 FLJ42627 SNORA10 NPRL3 SOX8 TPSAB1 C16orf59 RHBDF1 HBM E4F1 FAM234A LOC105371038 MCRIP2 LUC7L MIR6511B1 FBXL16 LOC107987233 MIR3180-5 RAB11FIP3 MIR6767 FAM173A ATP6V0C IFT140 ABCA3 ERVK13-1 AXIN1 NHLRC4 SPSB3 HBA2 RPL23AP5 NOXO1 WDR90 WDR24 MIR4516 SYNGR3 PTX4 TSR3 TMEM204 ECI1 RAB26 CCDC78 RNPS1 TBC1D24 LMF1-AS1 HBQ1 MIR3176 JMJD8 PIGQ PKD1 PDIA2 DECR2 SNORA78 NARFL CACNA1H MIR5587 C16orf91 TSC2 NTHL1 LOC105371049 ZNF598 MRPL28 MEIOB LOC105371046 GNG13 PRSS29P TBL3 SSTR5 NPW CHTF18 NME4 MIR3677 RAB40C MAPK8IP3 MPG MSRB1 TPSB2 TRAF7 PRR25 NTN3 NUBP2 LOC100134368 LMF1 UNKL RHBDL1 IGFALS C1QTNF8 SNORD60 CRAMP1 MIR4717 UBE2I DNASE1L2 KCTD5 PDPK1 ABCA17P RPL3L STUB1 BAIAP3 HBA1 HN1L LOC652276 AMDHD2 SNHG9 SNRNP25 LINC00235 CLCN7 SSTR5-AS1 MIR1225 NDUFB10 NME3 LOC105371045 CAPN15 CASKIN1 TPSG1 RPS2 PRSS27 RPUSD1 MRPS34 MIR662 PGP TMEM8A TELO2 LOC105371047 METRN MIR6859-4 WASIR2 SNORA64 TPSD1 GNPTG HS3ST6 MIR6768 MIR3177 CCDC154 SNHG19 LOC106660606 HAGH DDX11L10 GFER LINC00254 LOC107984876 LOC105371184 PRR35 RNF151 CCNF LOC729652 HBZ SLC9A3R2 WFIKKN1 MSLN RHOT2 MIR940
nsv571172	Chr.16:1764390 - 1817039 on Build GRCh38	Loss	HAGH MRPS34 EME2 IGFALS SPSB3 MAPK8IP3 NME3 NUBP2
nsv1160328	Chr.16:1704619 - 1797867 on Build GRCh38	Deletion	MRPS34 EME2 IGFALS SPSB3 MAPK8IP3 NME3 MIR3177 NUBP2
nsv571171	Chr.16:1757779 - 1804539 on Build GRCh38	Gain+Loss	MRPS34 EME2 IGFALS SPSB3 MAPK8IP3 NME3 NUBP2
dgv4856n54	Chr.16:1600945 - 1813519 on Build GRCh38	Loss	HAGH MRPS34 EME2 IGFALS IFT140 HN1L CRAMP1 LOC105371046 SPSB3 MAPK8IP3 NME3 MIR3177 NUBP2
nsv471069	Chr.16:1754356 - 1791032 on Build GRCh38	Loss	MRPS34 EME2 IGFALS SPSB3 MAPK8IP3 NME3 NUBP2
nsv1051692	Chr.16:1505070 - 1866102 on Build GRCh38	Loss	HAGH MRPS34 TMEM204 EME2 FAHD1 IGFALS IFT140 HN1L TELO2 LOC105371047 CRAMP1 MEIOB LOC105371046 SPSB3 MAPK8IP3 NME3 MIR3177 NUBP2
nsv827500	Chr.16:1761258 - 1795126 on Build GRCh38	Gain	MRPS34 EME2 IGFALS SPSB3 MAPK8IP3 NME3 NUBP2
nsv571173	Chr.16:1767596 - 1780436 on Build GRCh38	Loss	MRPS34 EME2 SPSB3 MAPK8IP3 NME3
nsv518641	Chr.16:1645775 - 1835631 on Build GRCh38	Loss	HAGH MRPS34 EME2 FAHD1 IGFALS HN1L CRAMP1 MEIOB SPSB3 MAPK8IP3 NME3 MIR3177 NUBP2
nsv457336	Chr.16:1752231 - 1791032 on Build GRCh38	Loss	MRPS34 EME2 IGFALS SPSB3 MAPK8IP3 NME3 NUBP2
nsv952900	Chr.16:1724500 - 1827999 on Build GRCh38	Deletion	HAGH MRPS34 EME2 FAHD1 IGFALS SPSB3 MAPK8IP3 NME3 MIR3177 NUBP2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

purine nucleotide metabolic process
nucleoside diphosphate phosphorylation
GTP biosynthetic process
pyrimidine nucleotide metabolic process
UTP biosynthetic process
CTP biosynthetic process
apoptotic process
nucleoside triphosphate biosynthetic process
regulation of apoptotic process

Function(s)

nucleoside diphosphate kinase activity
protein binding
ATP binding
metal ion binding