Hs01806215_cn

• Gene Symbol: IL2RB
• Assay Reference Genome Location: Chr.22:37128794 on build GRCh38
• Cytoband: 22q12.3

Target Gene Details

• Entrez Gene ID: 3560
• Gene Name: interleukin 2 receptor subunit beta
• Gene Aliases: CD122, IL15RB, P70-75
• Location: Chr.22:37125838-37149922 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IL2RB	NM_000878.3	10	1089	NP_000869.1
	AK312860.1	10	1083
	BC025691.1	10	1072	AAH25691.1
	CR456506.1	9	977	CAG30392.1
	M26062.1	10	1089	AAA59143.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829203	Chr.22:36998126 - 37773322 on Build GRCh38	Loss	LOC101927051 TMPRSS6 LGALS1 ELFN2 NOL12 GGA1 LOC100506271 C1QTNF6 TST PDXP CYTH4 TRIOBP IL2RB SSTR3 KCTD17 CARD10 TEX33 RAC2 MPST LOC102724378 CDC42EP1 LGALS2 SH3BP1 MFNG
nsv834187	Chr.22:36965603 - 37163260 on Build GRCh38	Loss	LL22NC01-81G9.3 TMPRSS6 KCTD17 TEX33 TST MPST IL2RB
esv34015	Chr.22:36966049 - 37189804 on Build GRCh38	Loss	LL22NC01-81G9.3 TMPRSS6 KCTD17 C1QTNF6 TEX33 TST MPST IL2RB
nsv459882	Chr.22:36967923 - 37161398 on Build GRCh38	Gain	LL22NC01-81G9.3 TMPRSS6 KCTD17 TEX33 TST MPST IL2RB

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
protein complex assembly
signal transduction
viral process
cytokine-mediated signaling pathway
natural killer cell activation
interleukin-2-mediated signaling pathway
negative regulation of apoptotic process
positive regulation of GTPase activity

Function(s)

interleukin-2 receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
interleukin-2 binding