Hs01817428_cn

• Gene Symbol: STK19
• Assay Reference Genome Location: Chr.6:31978930 on build GRCh38
• Cytoband: 6p21.33

Target Gene Details

• Entrez Gene ID: 8859
• Gene Name: serine/threonine kinase 19
• Gene Aliases: D6S60, D6S60E, G11, HLA-RP1, RP1
• Location: Chr.6:31971175-31981446 on Build GRCh38
• Assay Gene Location: Overlaps Intron 3 - Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
STK19	NM_004197.1			NP_004188.1
	NM_032454.1			NP_115830.1
	NR_026717.1
	AK302111.1
	AK307198.1
	BC110347.1			AAI10348.1
	BC121128.1
	BC121129.1
	BC143833.1
	L26260.1			AAA20122.1
	X77386.1			CAA54565.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv601970	Chr.6:31970674 - 31980252 on Build GRCh38	Loss	STK19 DXO
dgv10463n54	Chr.6:31817661 - 32683279 on Build GRCh38	Loss	HLA-DRB6 PPT2 EHMT2 BTNL2 SNORD48 CYP21A2 ZBTB12 C2-AS1 NEU1 PPT2-EGFL8 HLA-DRA C4B TNXA STK19 MIR1236 HLA-DRB5 EGFL8 C4A SLC44A4 RNF5 SKIV2L C6orf10 LOC100507547 HLA-DRB1 CFB TNXB AGPAT1 HLA-DQB1 PBX2 MIR6721 AGER ATF6B CYP21A1P FKBPL LOC101929163 SNORD52 DXO HLA-DQB1-AS1 MIR6833 C2 HSPA1B HLA-DQA1 HSPA1A GPSM3 HCG23 PRRT1 NELFE C6orf48 NOTCH4
nsv601971	Chr.6:31971488 - 32046679 on Build GRCh38	Gain	CYP21A1P C4B TNXA STK19 DXO CYP21A2 TNXB C4A
nsv428141	Chr.6:31903735 - 32125066 on Build GRCh38	Gain+Loss	C2 SKIV2L CYP21A2 C2-AS1 CFB TNXB ATF6B CYP21A1P C4B TNXA STK19 DXO MIR1236 C4A NELFE
nsv1126749	Chr.6:31457323 - 32594423 on Build GRCh38	Deletion	CLIC1 HLA-DRB6 HCG26 PPT2 LSM2 LY6G6E VARS EHMT2 LY6G6D BTNL2 SNORD48 CYP21A2 NFKBIL1 ZBTB12 LTB C2-AS1 AIF1 NCR3 NEU1 PPT2-EGFL8 HLA-DRA C4B TNXA STK19 SNORD117 GPANK1 LST1 MIR1236 HLA-DRB5 MICB EGFL8 C4A PRRC2A LOC102725068 SAPCD1 HCP5 SLC44A4 RNF5 SKIV2L C6orf10 LOC100507547 HLA-DRB1 CFB TNXB MIR4646 ABHD16A AGPAT1 BAG6 DDX39B SNORD84 PBX2 DDAH2 CSNK2B LOC100287329 MSH5 LY6G6C MIR6721 C6orf47 AGER MIR6832 SAPCD1-AS1 TNF ATP6V1G2 ATF6B CYP21A1P FKBPL LOC101929163 MCCD1 SNORD52 DDX39B-AS1 DXO C6orf25 MIR6833 HSPA1L APOM C2 VWA7 LY6G5C HSPA1B SNORA38 HSPA1A LY6G5B ATP6V1G2-DDX39B LTA GPSM3 MSH5-SAPCD1 HCG23 LY6G6F PRRT1 NELFE C6orf48 NOTCH4
dgv10403n54	Chr.6:31312324 - 32049763 on Build GRCh38	Loss	CLIC1 HCG26 LSM2 LY6G6E VARS EHMT2 LY6G6D SNORD48 CYP21A2 NFKBIL1 ZBTB12 LTB C2-AS1 AIF1 NCR3 NEU1 C4B TNXA STK19 SNORD117 GPANK1 LST1 MIR1236 MICB C4A PRRC2A LOC102725068 SAPCD1 HCP5 SLC44A4 HLA-B SKIV2L CFB TNXB MIR4646 MICA ABHD16A BAG6 DDX39B SNORD84 DDAH2 CSNK2B LOC100287329 MSH5 LY6G6C C6orf47 MIR6832 SAPCD1-AS1 TNF ATP6V1G2 CYP21A1P MCCD1 SNORD52 DDX39B-AS1 DXO C6orf25 MIR6891 HSPA1L APOM C2 VWA7 LY6G5C HSPA1B SNORA38 HSPA1A LY6G5B ATP6V1G2-DDX39B LTA MSH5-SAPCD1 LY6G6F NELFE C6orf48
nsv1073969	Chr.6:31456422 - 33480523 on Build GRCh38	Deletion	ZBTB9 ZBTB22 LY6G6E LY6G6D SNORD48 NFKBIL1 ZBTB12 HLA-DMA LTB C2-AS1 NEU1 PPT2-EGFL8 C4B STK19 GPANK1 LST1 PSMB8-AS1 MICB EGFL8 C4A KIFC1 LOC102725068 HCP5 RNF5 SKIV2L RXRB CFB TNXB ABHD16A PHF1 BAG6 DDX39B TAP2 MIR6834 VPS52 TAP1 MSH5 HLA-DMB MIR6721 HLA-DQB2 C6orf47 AGER MIR6832 SAPCD1-AS1 CUTA HLA-DOA HSD17B8 CYP21A1P MCCD1 SNORD52 COL11A2 DDX39B-AS1 DXO HLA-DQB1-AS1 MIR6833 APOM WDR46 HSPA1B SNORA38 HCG25 LY6G5B PPP1R2P1 MIR5004 DAXX MSH5-SAPCD1 HCG23 LY6G6F RPS18 C6orf48 MIR219A1 NOTCH4 MIR3135B CLIC1 HLA-DRB6 HCG26 PPT2 LSM2 MIR6873 VARS EHMT2 BTNL2 CYP21A2 AIF1 NCR3 HLA-DRA TNXA SNORD117 MIR1236 HLA-DPB2 HLA-DRB5 PRRC2A HCG24 SAPCD1 SLC44A4 PSMB8 C6orf10 HLA-DPA1 LOC100507547 HLA-DRB1 MIR4646 PFDN6 RING1 AGPAT1 SNORD84 HLA-DQB1 PBX2 BRD2 DDAH2 CSNK2B LOC100287329 HLA-DPB1 RGL2 LY6G6C B3GALT4 HLA-DOB TNF ATP6V1G2 PSMB9 ATF6B FKBPL LOC101929163 C6orf25 LOC100294145 HSPA1L SLC39A7 C2 VWA7 LY6G5C HLA-DQA1 HSPA1A ATP6V1G2-DDX39B LTA GPSM3 SYNGAP1 TAPBP PRRT1 NELFE HLA-DQA2
nsv1112900	Chr.6:31455323 - 33480423 on Build GRCh38	Deletion	ZBTB9 ZBTB22 LY6G6E LY6G6D SNORD48 NFKBIL1 ZBTB12 HLA-DMA LTB C2-AS1 NEU1 PPT2-EGFL8 C4B STK19 GPANK1 LST1 PSMB8-AS1 MICB EGFL8 C4A KIFC1 LOC102725068 HCP5 RNF5 SKIV2L RXRB CFB TNXB ABHD16A PHF1 BAG6 DDX39B TAP2 MIR6834 VPS52 TAP1 MSH5 HLA-DMB MIR6721 HLA-DQB2 C6orf47 AGER MIR6832 SAPCD1-AS1 CUTA HLA-DOA HSD17B8 CYP21A1P MCCD1 SNORD52 COL11A2 DDX39B-AS1 DXO HLA-DQB1-AS1 MIR6833 APOM WDR46 HSPA1B SNORA38 HCG25 LY6G5B PPP1R2P1 MIR5004 DAXX MSH5-SAPCD1 HCG23 LY6G6F RPS18 C6orf48 MIR219A1 NOTCH4 MIR3135B CLIC1 HLA-DRB6 HCG26 PPT2 LSM2 MIR6873 VARS EHMT2 BTNL2 CYP21A2 AIF1 NCR3 HLA-DRA TNXA SNORD117 MIR1236 HLA-DPB2 HLA-DRB5 PRRC2A HCG24 SAPCD1 SLC44A4 PSMB8 C6orf10 HLA-DPA1 LOC100507547 HLA-DRB1 MIR4646 PFDN6 RING1 AGPAT1 SNORD84 HLA-DQB1 PBX2 BRD2 DDAH2 CSNK2B LOC100287329 HLA-DPB1 RGL2 LY6G6C B3GALT4 HLA-DOB TNF ATP6V1G2 PSMB9 ATF6B FKBPL LOC101929163 C6orf25 LOC100294145 HSPA1L SLC39A7 C2 VWA7 LY6G5C HLA-DQA1 HSPA1A ATP6V1G2-DDX39B LTA GPSM3 SYNGAP1 TAPBP PRRT1 NELFE HLA-DQA2
nsv830628	Chr.6:31919777 - 31979823 on Build GRCh38	Loss	C2 STK19 SKIV2L DXO MIR1236 C2-AS1 CFB NELFE
dgv10404n54	Chr.6:31312550 - 32516591 on Build GRCh38	Loss	CLIC1 HCG26 PPT2 LSM2 LY6G6E VARS EHMT2 LY6G6D BTNL2 SNORD48 CYP21A2 NFKBIL1 ZBTB12 LTB C2-AS1 AIF1 NCR3 NEU1 PPT2-EGFL8 HLA-DRA C4B TNXA STK19 SNORD117 GPANK1 LST1 MIR1236 MICB EGFL8 C4A PRRC2A LOC102725068 SAPCD1 HCP5 SLC44A4 HLA-B RNF5 SKIV2L C6orf10 LOC100507547 CFB TNXB MIR4646 MICA ABHD16A AGPAT1 BAG6 DDX39B SNORD84 PBX2 DDAH2 CSNK2B LOC100287329 MSH5 LY6G6C MIR6721 C6orf47 AGER MIR6832 SAPCD1-AS1 TNF ATP6V1G2 ATF6B CYP21A1P FKBPL LOC101929163 MCCD1 SNORD52 DDX39B-AS1 DXO C6orf25 MIR6891 MIR6833 HSPA1L APOM C2 VWA7 LY6G5C HSPA1B SNORA38 HSPA1A LY6G5B ATP6V1G2-DDX39B LTA GPSM3 MSH5-SAPCD1 HCG23 LY6G6F PRRT1 NELFE C6orf48 NOTCH4
nsv284	Chr.6:31957962 - 32028944 on Build GRCh38	Deletion	CYP21A1P C4B TNXA STK19 SKIV2L DXO C4A NELFE

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

protein phosphorylation

Function(s)

protein serine/threonine kinase activity
ATP binding