Hs01826442_cn

• Gene Symbol: FSTL3
• Assay Reference Genome Location: Chr.19:677984 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 10272
• Gene Name: follistatin like 3
• Gene Aliases: FLRG, FSRP
• Location: Chr.19:676389-683392 on Build GRCh38
• Assay Gene Location: Overlaps Exon 2 - Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FSTL3	NM_005860.2			NP_005851.1
	AK291958.1
	AK313341.1
	AY358917.1			AAQ89276.1
	BC005839.2			AAH05839.1
	BX439786.2
	U76702.1			AAC64321.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv578163	Chr.19:629303 - 682010 on Build GRCh38	Loss	FSTL3 FGF22 RNF126 POLRMT
dgv134n111	Chr.19:607984 - 967584 on Build GRCh38	Deletion	RNU6-9 FSTL3 KISS1R PTBP1 MIR4745 RNF126 PRTN3 MIR3187 ELANE CFD PLPPR3 POLRMT LOC101928450 MED16 ARID3A FGF22 R3HDM4 PRSS57 MISP PALM AZU1 HCN2
nsv428360	Chr.19:232069 - 702131 on Build GRCh38	Gain	FSTL3 C2CD4C THEG RNF126 GZMM MIER2 POLRMT SHC2 CDC34 BSG MADCAM1 FGF22 PRSS57 PLPP2 LOC101929060 ODF3L2 TPGS1 HCN2
nsv577978	Chr.19:294526 - 782854 on Build GRCh38	Gain	FSTL3 C2CD4C THEG RNF126 GZMM MIER2 POLRMT LOC101928450 SHC2 CDC34 BSG MADCAM1 FGF22 PRSS57 LOC101929060 MISP ODF3L2 PALM TPGS1 HCN2
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	FSTL3 RNU6-2 C2CD4C ABCA7 THEG PTBP1 ARHGAP45 MIR4745 RNF126 MIR3187 PLPPR3 TMEM259 CDC34 MED16 MADCAM1 ARID3A R3HDM4 MISP PALM AZU1 TPGS1 HCN2 POLR2E RNU6-9 KISS1R GPX4 LOC105372235 CNN2 PRTN3 GRIN3B GZMM ELANE CFD POLRMT LOC101928450 SHC2 BSG FGF22 PRSS57 ODF3L2 WDR18
nsv470101	Chr.19:401714 - 1008505 on Build GRCh38	Loss	FSTL3 C2CD4C PTBP1 MIR4745 RNF126 MIR3187 PLPPR3 CDC34 MED16 MADCAM1 ARID3A R3HDM4 MISP PALM AZU1 TPGS1 HCN2 RNU6-9 KISS1R LOC105372235 PRTN3 GRIN3B GZMM ELANE CFD POLRMT LOC101928450 SHC2 BSG FGF22 PRSS57 ODF3L2 WDR18

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

extracellular matrix glycoprotein

Gene Ontology Categories:

Process(es)

ossification
kidney development
hematopoietic progenitor cell differentiation
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
spermatogenesis
male gonad development
positive regulation of cell-cell adhesion
lung development
adrenal gland development
negative regulation of BMP signaling pathway
negative regulation of activin receptor signaling pathway
negative regulation of osteoclast differentiation
positive regulation of transcription from RNA polymerase II promoter
cellular response to metal ion
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

Function(s)

fibronectin binding
protein binding
activin binding