Hs01860282_cn

• Gene Symbol: HDDC3
• Assay Reference Genome Location: Chr.15:90931250 on build GRCh38
• Cytoband: 15q26.1

Target Gene Details

• Entrez Gene ID: 374659
• Gene Name: HD domain containing 3
• Gene Aliases: (ppGpp)ase, MESH1
• Location: Chr.15:90930918-90932569 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HDDC3	NM_001286451.1	4	594	NP_001273380.1
	NM_198527.3	4	745	NP_940929.1
	NR_104447.1	4	637
	AK057584.1	1	1313
	BC033794.1	4	745	AAH33794.1
	BU633661.1	1	342
	CA450487.1	1	349
	CV573934.1	4	579

Target Gene Details

• Entrez Gene ID: 55898
• Gene Name: unc-45 myosin chaperone A
• Gene Aliases: GC-UNC45, GCUNC-45, GCUNC45, IRO039700, SMAP-1, SMAP1, UNC-45A
• Location: Chr.15:90929980-90954093 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
UNC45A	NM_001039675.1			NP_001034764.1
	XM_011521779.2			XP_011520081.1
	AK125721.1
	BC045635.1			AAH45635.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833090	Chr.15:90911195 - 91098519 on Build GRCh38	Loss	VPS33B LOC101926911 UNC45A RCCD1 PRC1-AS1 HDDC3 MAN2A2 PRC1
nsv515661	Chr.15:90866779 - 90981967 on Build GRCh38	Loss	FES UNC45A RCCD1 PRC1-AS1 HDDC3 FURIN MAN2A2 PRC1
nsv833089	Chr.15:90859910 - 90962961 on Build GRCh38	Loss	FES UNC45A RCCD1 HDDC3 FURIN MAN2A2

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

hydrolase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

guanosine tetraphosphate metabolic process
response to starvation
muscle organ development
cell differentiation
chaperone-mediated protein folding
cell-cell adhesion

Function(s)

protein binding
GTP diphosphokinase activity
guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity
metal ion binding
Hsp90 protein binding
cadherin binding involved in cell-cell adhesion