Hs01860835_cn

• Gene Symbol: CNOT3
• Assay Reference Genome Location: Chr.19:54143162 on build GRCh38
• Cytoband: 19q13.42

Target Gene Details

• Entrez Gene ID: 4849
• Gene Name: CCR4-NOT transcription complex subunit 3
• Gene Aliases: LENG2, NOT3, NOT3H
• Location: Chr.19:54137689-54155708 on Build GRCh38
• Assay Gene Location: Overlaps Exon 3 - Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CNOT3	NM_014516.3			NP_055331.1
	XM_005278279.1			XP_005278336.1
	XM_005278280.2			XP_005278337.1
	XM_005278281.1			XP_005278338.1
	XM_005278282.2			XP_005278339.1
	XM_011526992.1			XP_011525294.1
	XM_011526993.2			XP_011525295.1
	AB014591.1
	AF180474.1			AAF29828.1
	AK160386.1			BAD18729.1
	AK300434.1
	BC016474.1			AAH16474.1
	BQ439042.1
	DB076207.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3644782	Chr.19:54138064 - 54154026 on Build GRCh38	Gain	CNOT3
nsv515623	Chr.19:54102901 - 54179150 on Build GRCh38	Loss	PRPF31 CNOT3 TFPT MBOAT7 TMC4 NDUFA3 LENG1
nsv953613	Chr.19:54097214 - 54198733 on Build GRCh38	Deletion	PRPF31 CNOT3 TFPT MBOAT7 OSCAR TMC4 NDUFA3 LENG1 TSEN34
esv2718812	Chr.19:53184636 - 54322450 on Build GRCh38	Deletion	ZNF813 ZNF845 MIR519A1 MIR518E LILRA6 MIR371B MIR520F MIR515-1 OSCAR MIR518F ZNF331 MIR520H MIR373 MIR519A2 FAM90A27P MIR516A1 TARM1 LILRA5 CACNG7 RPS9 MIR935 MIR526A1 MIR1283-2 MIR521-1 MIR521-2 MIR512-1 MIR372 ZNF761 MIR371A ZNF765 ZNF677 BIRC8 MIR520C MIR520B DPRX TMC4 MIR519C MIR524 MIR523 MIR520G NLRP12 MIR516A2 MIR516B2 ZNF525 PRKCG MIR515-2 MIR519E TFPT TPM3P9 VSTM1 MIR517B MIR520E CACNG6 MIR526B VN1R2 MIR518A2 TSEN34 LILRB2 LOC105372457 MIR520A MIR525 LILRB3 MYADM LILRB5 MIR516B1 MIR518C MIR517A MIR498 PRPF31 CNOT3 ZNF818P ZNF665 MIR518A1 MIR518B VN1R4 MIR518D CACNG8 MIR1283-1 MIR527 LENG1 MIR1323 MIR512-2 MIR526A2 MIR4752 MBOAT7 MIR520D MIR522 MIR517C NDUFA3 MIR519D MIR519B LOC284379

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

general transcription factor

Gene Ontology Categories:

Process(es)

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
nuclear-transcribed mRNA poly(A) tail shortening
trophectodermal cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
negative regulation of translation
gene silencing by RNA
regulation of stem cell population maintenance

Function(s)

protein binding