Hs01888293_cn

• Gene Symbol: TACC3
• Assay Reference Genome Location: Chr.4:1728155 on build GRCh38
• Cytoband: 4p16.3

Target Gene Details

• Entrez Gene ID: 10460
• Gene Name: transforming acidic coiled-coil containing protein 3
• Gene Aliases: ERIC-1, ERIC1
• Location: Chr.4:1721383-1745178 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TACC3	NM_006342.2	4	908	NP_006333.1
	XM_005247929.2	4	906	XP_005247986.1
	XM_005247930.2			XP_005247987.1
	XM_011513386.2	4	906	XP_011511688.1
	XM_017007653.1	4	960	XP_016863142.1
	AF093543.1	4	861	AAD25964.1
	AF479620.1			AAN76993.1
	AJ243997.1	4	853	CAB53009.1
	AK225631.1	4	876
	AK302463.1	4	879
	AK304579.1	3	637
	AK310660.1	3	631
	BC106071.1	4	869	AAI06072.1
	BC111771.1	4	821	AAI11772.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428434	Chr.4:1623665 - 1813048 on Build GRCh38	Gain	TMEM129 SLBP LETM1 TACC3 FAM53A FGFR3
nsv949756	Chr.4:1710274 - 1817773 on Build GRCh38	Deletion	TMEM129 SLBP LETM1 TACC3 FGFR3
dgv8901n54	Chr.4:1644637 - 1864631 on Build GRCh38	Loss	TMEM129 SLBP LETM1 TACC3 FAM53A FGFR3
nsv593316	Chr.4:1526039 - 1768630 on Build GRCh38	Gain	TMEM129 SLBP TACC3 FAM53A
nsv508989	Chr.4:1623823 - 1846590 on Build GRCh38	Insertion	TMEM129 SLBP LETM1 TACC3 FAM53A FGFR3
nsv1161027	Chr.4:1699833 - 1750693 on Build GRCh38	Deletion	TMEM129 SLBP TACC3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

microtubule cytoskeleton organization
cell proliferation
cerebral cortex development

Function(s)

protein binding