Hs01926196_cn

• Gene Symbol: APOM
• Assay Reference Genome Location: Chr.6:31655955 on build GRCh38
• Cytoband: 6p21.33

Target Gene Details

• Entrez Gene ID: 55937
• Gene Name: apolipoprotein M
• Gene Aliases: G3a, HSPC336, NG20, apo-M
• Location: Chr.6:31652410-31658210 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
APOM	NM_001256169.1			NP_001243098.1
	NM_019101.2	1	62	NP_061974.2
	NR_045828.1
	XM_006715150.3	1	39	XP_006715213.1
	AA846749.1
	AF118393.3			AAD11443.2
	AF161454.1			AAF29014.1
	AJ245434.1	1	39	CAB51604.1
	BC020683.1	1	41	AAH20683.1
	BF344944.1
	BG564719.1	1	63
	CB054016.1
	CN428415.1

Target Gene Details

• Entrez Gene ID: 7917
• Gene Name: BCL2 associated athanogene 6
• Gene Aliases: BAG-6, BAT3, D6S52E, G3
• Location: Chr.6:31639028-31660900 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BAG6	XM_017011279.1			XP_016866768.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv462871	Chr.6:31607499 - 31664357 on Build GRCh38	Loss	PRRC2A BAG6 GPANK1 SNORA38 C6orf47 APOM AIF1 MIR6832
nsv1126749	Chr.6:31457323 - 32594423 on Build GRCh38	Deletion	VWA7 BAG6 HSPA1A AGPAT1 NCR3 LOC101929163 HCG26 SAPCD1-AS1 APOM DDAH2 CLIC1 C2 LOC102725068 LY6G6E SLC44A4 SNORD52 EHMT2 HCP5 HLA-DRA CYP21A2 DDX39B-AS1 C6orf47 ABHD16A NFKBIL1 AIF1 HLA-DRB5 FKBPL SAPCD1 TNF HLA-DRB1 ZBTB12 ATF6B C4B NELFE MSH5-SAPCD1 STK19 TNXA VARS LY6G5B GPANK1 CFB C2-AS1 MICB DDX39B LTA MIR6721 TNXB ATP6V1G2 HCG23 SNORA38 C6orf48 HSPA1B HSPA1L MIR6832 PPT2-EGFL8 MIR4646 PPT2 C6orf10 MIR6833 AGER LY6G6C RNF5 GPSM3 SNORD48 PRRC2A PBX2 HLA-DRB6 C4A BTNL2 SKIV2L NOTCH4 LSM2 LY6G6F DXO C6orf25 MCCD1 LY6G5C NEU1 LTB CYP21A1P CSNK2B SNORD84 MIR1236 LST1 MSH5 LOC100287329 LY6G6D ATP6V1G2-DDX39B LOC100507547 EGFL8 PRRT1 SNORD117
nsv1073969	Chr.6:31456422 - 33480523 on Build GRCh38	Deletion	VWA7 BAG6 AGPAT1 LOC101929163 SAPCD1-AS1 APOM CLIC1 HLA-DQB2 EHMT2 HCP5 HLA-DQA1 HLA-DOA DDX39B-AS1 NFKBIL1 RPS18 HLA-DRB5 HLA-DMA SAPCD1 TNF ZBTB12 ATF6B C4B MIR219A1 MSH5-SAPCD1 STK19 HLA-DOB CFB C2-AS1 MICB DDX39B LTA MIR6721 DAXX ATP6V1G2 HCG23 VPS52 C6orf48 HSPA1B RXRB PPT2-EGFL8 WDR46 HCG24 MIR6833 HLA-DQA2 GPSM3 SNORD48 PRRC2A HLA-DRB6 C4A MIR6873 ZBTB22 SKIV2L NOTCH4 LSM2 DXO NEU1 LTB HLA-DPB2 CYP21A1P CSNK2B PFDN6 MIR1236 MSH5 LY6G6D LOC100507547 EGFL8 HLA-DPB1 SNORD117 HLA-DQB1 PSMB8-AS1 RGL2 KIFC1 HSPA1A NCR3 HCG26 DDAH2 C2 LOC102725068 LY6G6E SLC44A4 SNORD52 HLA-DRA CYP21A2 C6orf47 ABHD16A LOC100294145 AIF1 FKBPL SYNGAP1 HLA-DRB1 NELFE SLC39A7 TNXA VARS LY6G5B TAP2 GPANK1 ZBTB9 PPP1R2P1 TNXB TAPBP SNORA38 HCG25 HSPA1L HLA-DQB1-AS1 MIR6832 COL11A2 PHF1 HLA-DMB MIR4646 PPT2 MIR5004 HSD17B8 C6orf10 MIR6834 CUTA AGER LY6G6C RNF5 PBX2 PSMB8 BTNL2 RING1 TAP1 MIR3135B B3GALT4 LY6G6F C6orf25 BRD2 MCCD1 LY6G5C HLA-DPA1 SNORD84 PSMB9 LST1 LOC100287329 ATP6V1G2-DDX39B PRRT1
dgv10403n54	Chr.6:31312324 - 32049763 on Build GRCh38	Loss	VWA7 BAG6 HSPA1A NCR3 HCG26 SAPCD1-AS1 MIR6891 APOM DDAH2 CLIC1 C2 LOC102725068 LY6G6E SLC44A4 SNORD52 EHMT2 HCP5 CYP21A2 DDX39B-AS1 C6orf47 ABHD16A NFKBIL1 AIF1 SAPCD1 TNF ZBTB12 HLA-B C4B NELFE MSH5-SAPCD1 STK19 TNXA VARS LY6G5B GPANK1 CFB C2-AS1 MICB DDX39B LTA TNXB ATP6V1G2 SNORA38 C6orf48 HSPA1B HSPA1L MIR6832 MIR4646 LY6G6C SNORD48 PRRC2A C4A SKIV2L LSM2 LY6G6F DXO C6orf25 MICA MCCD1 LY6G5C NEU1 LTB CYP21A1P CSNK2B SNORD84 MIR1236 LST1 MSH5 LOC100287329 LY6G6D ATP6V1G2-DDX39B SNORD117
nsv1112900	Chr.6:31455323 - 33480423 on Build GRCh38	Deletion	VWA7 BAG6 AGPAT1 LOC101929163 SAPCD1-AS1 APOM CLIC1 HLA-DQB2 EHMT2 HCP5 HLA-DQA1 HLA-DOA DDX39B-AS1 NFKBIL1 RPS18 HLA-DRB5 HLA-DMA SAPCD1 TNF ZBTB12 ATF6B C4B MIR219A1 MSH5-SAPCD1 STK19 HLA-DOB CFB C2-AS1 MICB DDX39B LTA MIR6721 DAXX ATP6V1G2 HCG23 VPS52 C6orf48 HSPA1B RXRB PPT2-EGFL8 WDR46 HCG24 MIR6833 HLA-DQA2 GPSM3 SNORD48 PRRC2A HLA-DRB6 C4A MIR6873 ZBTB22 SKIV2L NOTCH4 LSM2 DXO NEU1 LTB HLA-DPB2 CYP21A1P CSNK2B PFDN6 MIR1236 MSH5 LY6G6D LOC100507547 EGFL8 HLA-DPB1 SNORD117 HLA-DQB1 PSMB8-AS1 RGL2 KIFC1 HSPA1A NCR3 HCG26 DDAH2 C2 LOC102725068 LY6G6E SLC44A4 SNORD52 HLA-DRA CYP21A2 C6orf47 ABHD16A LOC100294145 AIF1 FKBPL SYNGAP1 HLA-DRB1 NELFE SLC39A7 TNXA VARS LY6G5B TAP2 GPANK1 ZBTB9 PPP1R2P1 TNXB TAPBP SNORA38 HCG25 HSPA1L HLA-DQB1-AS1 MIR6832 COL11A2 PHF1 HLA-DMB MIR4646 PPT2 MIR5004 HSD17B8 C6orf10 MIR6834 CUTA AGER LY6G6C RNF5 PBX2 PSMB8 BTNL2 RING1 TAP1 MIR3135B B3GALT4 LY6G6F C6orf25 BRD2 MCCD1 LY6G5C HLA-DPA1 SNORD84 PSMB9 LST1 LOC100287329 ATP6V1G2-DDX39B PRRT1
dgv10404n54	Chr.6:31312550 - 32516591 on Build GRCh38	Loss	VWA7 BAG6 HSPA1A AGPAT1 NCR3 LOC101929163 HCG26 SAPCD1-AS1 MIR6891 APOM DDAH2 CLIC1 C2 LOC102725068 LY6G6E SLC44A4 SNORD52 EHMT2 HCP5 HLA-DRA CYP21A2 DDX39B-AS1 C6orf47 ABHD16A NFKBIL1 AIF1 FKBPL SAPCD1 TNF ZBTB12 HLA-B ATF6B C4B NELFE MSH5-SAPCD1 STK19 TNXA VARS LY6G5B GPANK1 CFB C2-AS1 MICB DDX39B LTA MIR6721 TNXB ATP6V1G2 HCG23 SNORA38 C6orf48 HSPA1B HSPA1L MIR6832 PPT2-EGFL8 MIR4646 PPT2 C6orf10 MIR6833 AGER LY6G6C RNF5 GPSM3 SNORD48 PRRC2A PBX2 C4A BTNL2 SKIV2L NOTCH4 LSM2 LY6G6F DXO C6orf25 MICA MCCD1 LY6G5C NEU1 LTB CYP21A1P CSNK2B SNORD84 MIR1236 LST1 MSH5 LOC100287329 LY6G6D ATP6V1G2-DDX39B LOC100507547 EGFL8 PRRT1 SNORD117
nsv1161370	Chr.6:31600692 - 31714252 on Build GRCh38	Deletion	PRRC2A BAG6 SNORA38 APOM LY6G6F MIR6832 LY6G5C CSNK2B LY6G6E LY6G5B GPANK1 MIR4646 C6orf47 ABHD16A AIF1
nsv830627	Chr.6:31528437 - 31692173 on Build GRCh38	Loss	BAG6 ATP6V1G2 NCR3 SNORA38 APOM MIR6832 DDX39B-AS1 C6orf47 ABHD16A NFKBIL1 AIF1 PRRC2A TNF MCCD1 LY6G5C LTB CSNK2B SNORD84 LY6G5B LST1 GPANK1 LOC100287329 ATP6V1G2-DDX39B SNORD117 DDX39B LTA

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

apolipoprotein, transfer/carrier protein, chaperone

Gene Ontology Categories:

Process(es)

retinoid metabolic process
response to glucose
cholesterol efflux
high-density lipoprotein particle remodeling
high-density lipoprotein particle assembly
high-density lipoprotein particle clearance
negative regulation of plasma lipoprotein particle oxidation
lipoprotein metabolic process
cholesterol homeostasis
reverse cholesterol transport
cellular oxidant detoxification
kidney development
immune system process
ubiquitin-dependent protein catabolic process
transport
synaptonemal complex assembly
spermatogenesis
brain development
embryo development
covalent chromatin modification
internal peptidyl-lysine acetylation
cell differentiation
lung development
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of apoptotic process
negative regulation of proteolysis
protein stabilization
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
tail-anchored membrane protein insertion into ER membrane
positive regulation of ERAD pathway
maintenance of unfolded protein involved in ERAD pathway
protein localization to cytosolic proteasome complex involved in ERAD pathway

Function(s)

lipid transporter activity
phospholipid binding
antioxidant activity
protein binding
Hsp70 protein binding
polyubiquitin binding
ubiquitin protein ligase binding
ribosome binding
misfolded protein binding
proteasome binding
ubiquitin-specific protease binding