Hs01926196_cn

• Gene Symbol: APOM
• Assay Reference Genome Location: Chr.6:31655955 on build GRCh38
• Cytoband: 6p21.33

Target Gene Details

• Entrez Gene ID: 55937
• Gene Name: apolipoprotein M
• Gene Aliases: G3a, HSPC336, NG20, apo-M
• Location: Chr.6:31652410-31658210 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
APOM	NM_001256169.1			NP_001243098.1
	NM_019101.2	1	62	NP_061974.2
	NR_045828.1
	XM_006715150.3	1	39	XP_006715213.1
	AA846749.1
	AF118393.3			AAD11443.2
	AF161454.1			AAF29014.1
	AJ245434.1	1	39	CAB51604.1
	BC020683.1	1	41	AAH20683.1
	BF344944.1
	BG564719.1	1	63
	CB054016.1
	CN428415.1

Target Gene Details

• Entrez Gene ID: 7917
• Gene Name: BCL2 associated athanogene 6
• Gene Aliases: BAG-6, BAT3, D6S52E, G3
• Location: Chr.6:31639028-31660900 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BAG6	XM_017011279.1			XP_016866768.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1126749	Chr.6:31457323 - 32594423 on Build GRCh38	Deletion	CYP21A1P MIR6721 LTA HSPA1B LOC102725068 PBX2 PRRT1 SNORD117 DDX39B-AS1 VWA7 LTB SAPCD1-AS1 TNXA EHMT2 BTNL2 C6orf48 MIR6833 DDX39B MIR6832 VARS LOC100287329 TNF C6orf47 MICB GPSM3 FKBPL CYP21A2 HLA-DRB5 NELFE LY6G5C GPANK1 ATF6B LY6G6F ABHD16A ATP6V1G2-DDX39B NOTCH4 LOC101929163 BAG6 HSPA1A LSM2 AIF1 LY6G6D TNXB LY6G6E RNF5 PPT2-EGFL8 CFB HLA-DRA SLC44A4 SNORD52 NCR3 MSH5-SAPCD1 HCG23 HLA-DRB1 PPT2 SNORD48 LY6G5B LY6G6C C4B SNORA38 DXO STK19 HCG26 MIR4646 EGFL8 HLA-DRB6 NFKBIL1 PRRC2A HCP5 CLIC1 C6orf10 SKIV2L HSPA1L AGPAT1 NEU1 LOC100507547 SAPCD1 DDAH2 ATP6V1G2 AGER APOM SNORD84 C2-AS1 MSH5 LST1 CSNK2B C6orf25 C2 MCCD1 C4A ZBTB12 MIR1236
nsv601942	Chr.6:31607499 - 31664357 on Build GRCh38	Loss	AIF1 GPANK1 APOM SNORA38 C6orf47 PRRC2A BAG6 MIR6832
dgv10403n54	Chr.6:31312324 - 32049763 on Build GRCh38	Loss	CYP21A1P LTA HSPA1B LOC102725068 SNORD117 DDX39B-AS1 VWA7 LTB SAPCD1-AS1 TNXA EHMT2 C6orf48 DDX39B MIR6832 VARS LOC100287329 TNF C6orf47 MICB CYP21A2 NELFE LY6G5C GPANK1 LY6G6F ABHD16A ATP6V1G2-DDX39B MIR6891 BAG6 HSPA1A LSM2 AIF1 LY6G6D TNXB LY6G6E CFB SLC44A4 SNORD52 NCR3 MSH5-SAPCD1 SNORD48 LY6G5B LY6G6C C4B SNORA38 DXO STK19 HCG26 MIR4646 NFKBIL1 PRRC2A HCP5 CLIC1 MICA SKIV2L HSPA1L NEU1 HLA-B SAPCD1 DDAH2 ATP6V1G2 APOM SNORD84 C2-AS1 MSH5 LST1 CSNK2B C6orf25 C2 MCCD1 C4A ZBTB12 MIR1236
nsv1073969	Chr.6:31456422 - 33480523 on Build GRCh38	Deletion	CYP21A1P TAP1 LOC102725068 PBX2 HLA-DQA1 PRRT1 SNORD117 MIR3135B HLA-DQB1 DDX39B-AS1 VWA7 LTB TNXA EHMT2 MIR6833 DDX39B MIR6832 VARS TNF HCG24 GPSM3 CYP21A2 HLA-DOA HLA-DRB5 COL11A2 PPP1R2P1 LY6G6F KIFC1 ATP6V1G2-DDX39B LOC101929163 BAG6 SYNGAP1 CUTA TAP2 LSM2 AIF1 HSD17B8 LY6G6E PPT2-EGFL8 SLC44A4 NCR3 MSH5-SAPCD1 HLA-DPB2 HLA-DRB1 PSMB8 PPT2 SNORD48 PSMB8-AS1 HLA-DPB1 HLA-DQB1-AS1 C4B SNORA38 DXO HLA-DRB6 NFKBIL1 PRRC2A C6orf10 MIR219A1 HSPA1L AGPAT1 RING1 LOC100507547 SAPCD1 DDAH2 ATP6V1G2 AGER HLA-DMA APOM CSNK2B C6orf25 C2 C4A MIR1236 MIR6721 LTA HSPA1B PHF1 PSMB9 ZBTB9 SAPCD1-AS1 PFDN6 BTNL2 RXRB C6orf48 RGL2 WDR46 MIR5004 B3GALT4 LOC100287329 ZBTB22 C6orf47 MICB FKBPL VPS52 NELFE LY6G5C DAXX GPANK1 ATF6B TAPBP ABHD16A NOTCH4 HLA-DPA1 HSPA1A LY6G6D HCG25 TNXB MIR6834 HLA-DMB RNF5 HLA-DQB2 CFB HLA-DRA SNORD52 HCG23 LOC100294145 HLA-DQA2 LY6G5B LY6G6C STK19 HCG26 MIR4646 EGFL8 HCP5 CLIC1 SKIV2L RPS18 NEU1 SLC39A7 BRD2 HLA-DOB SNORD84 C2-AS1 MIR6873 MSH5 LST1 MCCD1 ZBTB12
nsv1112900	Chr.6:31455323 - 33480423 on Build GRCh38	Deletion	CYP21A1P TAP1 LOC102725068 PBX2 HLA-DQA1 PRRT1 SNORD117 MIR3135B HLA-DQB1 DDX39B-AS1 VWA7 LTB TNXA EHMT2 MIR6833 DDX39B MIR6832 VARS TNF HCG24 GPSM3 CYP21A2 HLA-DOA HLA-DRB5 COL11A2 PPP1R2P1 LY6G6F KIFC1 ATP6V1G2-DDX39B LOC101929163 BAG6 SYNGAP1 CUTA TAP2 LSM2 AIF1 HSD17B8 LY6G6E PPT2-EGFL8 SLC44A4 NCR3 MSH5-SAPCD1 HLA-DPB2 HLA-DRB1 PSMB8 PPT2 SNORD48 PSMB8-AS1 HLA-DPB1 HLA-DQB1-AS1 C4B SNORA38 DXO HLA-DRB6 NFKBIL1 PRRC2A C6orf10 MIR219A1 HSPA1L AGPAT1 RING1 LOC100507547 SAPCD1 DDAH2 ATP6V1G2 AGER HLA-DMA APOM CSNK2B C6orf25 C2 C4A MIR1236 MIR6721 LTA HSPA1B PHF1 PSMB9 ZBTB9 SAPCD1-AS1 PFDN6 BTNL2 RXRB C6orf48 RGL2 WDR46 MIR5004 B3GALT4 LOC100287329 ZBTB22 C6orf47 MICB FKBPL VPS52 NELFE LY6G5C DAXX GPANK1 ATF6B TAPBP ABHD16A NOTCH4 HLA-DPA1 HSPA1A LY6G6D HCG25 TNXB MIR6834 HLA-DMB RNF5 HLA-DQB2 CFB HLA-DRA SNORD52 HCG23 LOC100294145 HLA-DQA2 LY6G5B LY6G6C STK19 HCG26 MIR4646 EGFL8 HCP5 CLIC1 SKIV2L RPS18 NEU1 SLC39A7 BRD2 HLA-DOB SNORD84 C2-AS1 MIR6873 MSH5 LST1 MCCD1 ZBTB12
dgv10404n54	Chr.6:31312550 - 32516591 on Build GRCh38	Loss	CYP21A1P MIR6721 LTA HSPA1B LOC102725068 PBX2 PRRT1 SNORD117 DDX39B-AS1 VWA7 LTB SAPCD1-AS1 TNXA EHMT2 BTNL2 C6orf48 MIR6833 DDX39B MIR6832 VARS LOC100287329 TNF C6orf47 MICB GPSM3 FKBPL CYP21A2 NELFE LY6G5C GPANK1 ATF6B LY6G6F ABHD16A ATP6V1G2-DDX39B NOTCH4 LOC101929163 MIR6891 BAG6 HSPA1A LSM2 AIF1 LY6G6D TNXB LY6G6E RNF5 PPT2-EGFL8 CFB HLA-DRA SLC44A4 SNORD52 NCR3 MSH5-SAPCD1 HCG23 PPT2 SNORD48 LY6G5B LY6G6C C4B SNORA38 DXO STK19 HCG26 MIR4646 EGFL8 NFKBIL1 PRRC2A HCP5 CLIC1 C6orf10 MICA SKIV2L HSPA1L AGPAT1 NEU1 LOC100507547 HLA-B SAPCD1 DDAH2 ATP6V1G2 AGER APOM SNORD84 C2-AS1 MSH5 LST1 CSNK2B C6orf25 C2 MCCD1 C4A ZBTB12 MIR1236
nsv1161370	Chr.6:31600692 - 31714252 on Build GRCh38	Deletion	AIF1 LY6G6E C6orf47 LY6G5C GPANK1 LY6G5B APOM SNORA38 LY6G6F ABHD16A MIR4646 CSNK2B PRRC2A BAG6 MIR6832
nsv830627	Chr.6:31528437 - 31692173 on Build GRCh38	Loss	AIF1 LTA NCR3 SNORD117 DDX39B-AS1 LY6G5B LTB SNORA38 DDX39B NFKBIL1 PRRC2A MIR6832 LOC100287329 TNF C6orf47 LY6G5C ATP6V1G2 GPANK1 APOM SNORD84 ABHD16A LST1 ATP6V1G2-DDX39B CSNK2B BAG6 MCCD1

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

apolipoprotein, transfer/carrier protein, chaperone

Gene Ontology Categories:

Process(es)

retinoid metabolic process
response to glucose
cholesterol efflux
high-density lipoprotein particle remodeling
high-density lipoprotein particle assembly
high-density lipoprotein particle clearance
negative regulation of plasma lipoprotein particle oxidation
lipoprotein metabolic process
cholesterol homeostasis
reverse cholesterol transport
cellular oxidant detoxification
kidney development
immune system process
ubiquitin-dependent protein catabolic process
transport
synaptonemal complex assembly
spermatogenesis
brain development
embryo development
covalent chromatin modification
internal peptidyl-lysine acetylation
cell differentiation
lung development
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of apoptotic process
negative regulation of proteolysis
protein stabilization
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
tail-anchored membrane protein insertion into ER membrane
positive regulation of ERAD pathway
maintenance of unfolded protein involved in ERAD pathway
protein localization to cytosolic proteasome complex involved in ERAD pathway

Function(s)

lipid transporter activity
phospholipid binding
antioxidant activity
protein binding
Hsp70 protein binding
polyubiquitin binding
ubiquitin protein ligase binding
ribosome binding
misfolded protein binding
proteasome binding
ubiquitin-specific protease binding